Rv3855 - tetR-family transcriptional repressor ethR

Expression: Most Significant Conditions for Rv3855

Protein Domains

Gene Information
Locus	Rv3855
Symbol	ethR
Gene Name	tetR-family transcriptional repressor ethR
Location	4327549 - 4328199 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:651 bp Protein:217 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	36563
Related Genes	MAP0179c MAV_0173 Mkms_5146 Mkms_5442 ML0064 Mmcs_5058 Mmcs_5353 MSMEG_1611 MSMEG_6441 MT3970 MUL_5027 Mvan_5684 nfa47000 SAV1778 SAV1781 SAV2263 SAV2268 SAV2270
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3855
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3855 Transcript 1
MTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT
FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV
TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE
RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR*

Genomic Sequence

>Rv3855
GTGACCACCTCCGCGGCCAGTCAGGCTTCGCTGCCTAGGGGCCGGCGCACCGCGCGGCCG
TCCGGCGACGATCGTGAACTGGCGATCCTCGCCACCGCCGAGAACCTTCTCGAGGACCGT
CCGCTGGCCGATATCTCGGTCGACGATCTGGCCAAGGGCGCCGGTATCTCGAGGCCGACG
TTCTACTTCTATTTCCCATCCAAGGAAGCGGTGCTGCTGACCCTGCTGGACCGGGTGGTC
AATCAAGCCGACATGGCCCTACAGACCCTTGCCGAGAATCCCGCCGACACCGACCGCGAG
AACATGTGGCGCACCGGGATCAACGTGTTCTTCGAGACATTCGGGTCGCACAAGGCGGTA
ACCCGAGCCGGTCAGGCCGCCAGGGCAACCAGTGTCGAAGTCGCCGAACTGTGGTCGACG
TTTATGCAGAAGTGGATCGCCTACACGGCCGCCGTGATCGACGCCGAACGCGACCGAGGC
GCGGCGCCGCGCACCCTGCCGGCCCATGAACTGGCCACAGCGCTCAACCTGATGAACGAG
CGGACGCTGTTCGCGTCATTCGCCGGCGAACAGCCCTCGGTGCCGGAAGCCCGCGTGCTG
GATACGCTGGTGCACATCTGGGTGACCAGCATTTACGGCGAGAACCGCTAA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv3854c	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) AR. Baulard, JC. Betts et al. Activation of the pro-drug ethionamide is regulated in mycobacteria. J. Biol. Chem. 2000
Interaction	Regulatory Rv3854c	active	priti.priety	2012-10-05
	Co-expression (Functional linkage) AR. Baulard, JC. Betts et al. Activation of the pro-drug ethionamide is regulated in mycobacteria. J. Biol. Chem. 2000
Interaction	Regulates Rv3854c	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008