Rv3892c - PPE family protein

Expression: Most Significant Conditions for Rv3892c

Protein Domains

Gene Information
Locus	Rv3892c
Symbol	PPE69
Gene Name	PPE family protein
Location	4374484 - 4375683 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1200 bp Protein:400 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	11838
Related Genes	MAP0158 MT4007
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3892c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3892c Transcript 1
MPDPGWAARTPEANDLLLTAGTGVGTHLANQTAWTTLGASHHASGVASAINTAATAASWL
GVGSAASALNVTMLNATLHGLAGWVDVKPAVVSTAIAAFETANAAMRPAPECMENRDEWG
VDNAINPSVLWTLTPRIVSLDVEYFGVMWPNNAAVGATYGGVLAALAESLAIPPPVATMG
ASPAAPAQAAAAVGQAAAEAAAGDGMRSAYQGVQAGSTGAGQSTSAGENFGNQLSTFMQP
MQAVMQAAPQALQAPSGLMQAPMSAMQPLQSMVGMFANPGALGMGGAAPGASAASAAGGI
SAAATEVGAGGGGAALGGGGMPATSFTRPVSAFESGTSGRPVGLRPSGALGADVVRAPTT
TVGGTPIGGMPVGHAAGGHRGSHGKSEQAATVRVVDDRR*

Genomic Sequence

>Rv3892c
ATGCCCGATCCAGGATGGGCTGCGCGGACACCTGAGGCCAACGACCTGCTGCTCACGGCG
GGCACCGGCGTGGGCACCCATCTGGCCAATCAAACGGCGTGGACCACACTGGGCGCCAGC
CACCACGCCTCGGGTGTCGCGTCGGCGATCAACACCGCCGCCACCGCGGCGAGCTGGTTG
GGTGTCGGGTCGGCGGCCTCGGCGCTTAACGTCACCATGCTCAACGCCACGCTGCACGGA
CTGGCCGGCTGGGTCGACGTGAAGCCGGCCGTGGTATCGACCGCGATCGCGGCGTTTGAG
ACCGCCAACGCGGCCATGCGCCCTGCCCCCGAGTGCATGGAGAACCGCGACGAATGGGGC
GTCGACAACGCCATCAACCCCAGCGTGCTGTGGACACTAACGCCTCGAATCGTCTCTTTG
GACGTCGAGTATTTCGGGGTGATGTGGCCGAATAACGCCGCGGTGGGCGCCACCTACGGA
GGGGTTCTCGCCGCGCTGGCCGAGAGTCTGGCAATTCCGCCGCCGGTCGCGACCATGGGT
GCATCTCCGGCCGCTCCGGCACAGGCTGCGGCGGCGGTTGGCCAGGCGGCCGCCGAGGCC
GCGGCCGGTGACGGGATGCGTTCCGCCTACCAGGGCGTGCAGGCAGGGTCAACCGGCGCG
GGTCAGTCAACGTCGGCGGGTGAGAACTTCGGCAATCAGCTCAGCACGTTCATGCAGCCG
ATGCAGGCGGTGATGCAAGCGGCCCCGCAGGCGCTGCAGGCGCCGTCGGGACTGATGCAG
GCACCGATGAGCGCGATGCAGCCGCTGCAATCGATGGTGGGCATGTTCGCCAACCCGGGC
GCACTGGGCATGGGCGGGGCGGCGCCGGGAGCCTCGGCGGCTTCGGCGGCCGGTGGGATA
TCGGCCGCGGCCACCGAGGTCGGTGCGGGCGGCGGAGGCGCCGCCCTGGGCGGCGGCGGT
ATGCCAGCGACGAGCTTCACACGTCCCGTCAGCGCTTTCGAATCGGGCACCAGCGGCAGG
CCGGTCGGGTTGCGGCCCAGCGGGGCTTTGGGCGCCGACGTCGTGCGCGCGCCGACGACC
ACGGTGGGTGGCACCCCTATCGGAGGCATGCCGGTCGGACATGCGGCGGGGGGTCACCGC
GGATCCCATGGCAAGTCCGAGCAGGCCGCGACGGTGCGTGTTGTCGATGACCGGCGGTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	PhysicalInteraction Rv3893c	active	shahanup86	2012-10-05
	Gene Neighborhood (Functional linkage) NC. Gey Van Pittius, J. Gamieldien et al. The ESAT-6 gene cluster of Mycobacterium tuberculosis and other high G+C Gram-positive bacteria. Genome Biol. 2001
Interaction	PhysicalInteraction Rv3893c	active	shahanup86	2012-10-05
	Gene Neighborhood (Functional linkage) authors,NC. Gey van Pittius,SL. Sampson,H. Lee,Y. Kim,PD. van Helden,RM. Warren Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions. BMC Evol. Biol. 2006
Interaction	PhysicalInteraction Rv3893c	active	shahanup86	2012-10-05
	Gene Neighborhood (Functional linkage) authors,M. Strong,MR. Sawaya,S. Wang,M. Phillips,D. Cascio,D. Eisenberg Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A. 2006
Interaction	PhysicalInteraction Rv3893c	active	shahanup86	2012-10-05
	Gene Neighborhood (Functional linkage) NC. Gey Van Pittius, J. Gamieldien et al. The ESAT-6 gene cluster of Mycobacterium tuberculosis and other high G+C Gram-positive bacteria. Genome Biol. 2001
Interaction	PhysicalInteraction Rv3893c	active	shahanup86	2012-10-05
	Gene Neighborhood (Functional linkage) authors,NC. Gey van Pittius,SL. Sampson,H. Lee,Y. Kim,PD. van Helden,RM. Warren Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions. BMC Evol. Biol. 2006
Interaction	PhysicalInteraction Rv3893c	active	shahanup86	2012-10-05
	Gene Neighborhood (Functional linkage) authors,M. Strong,MR. Sawaya,S. Wang,M. Phillips,D. Cascio,D. Eisenberg Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A. 2006