Rv0003 - DNA replication and repair protein recF
Protein Domains

Gene Information
LocusRv0003
SymbolrecF
Gene NameDNA replication and repair protein recF
Location3280 - 4437 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:1158 bp
Protein:386 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number2
Related GenesAcel_0003 BL0637 CE0004 cg0005 DIP0003 jk0003 MAP0003 MAV_0003 Mkms_0012 ML0003 Mmcs_0004 MSMEG_0003 MT0003 MUL_0003 Mvan_0004 nfa30 PPA0004 RHA1_ro03669 RSP_1344 SAV4319
Transcriptional Regulation
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Regulatory Network
Search for regulators of Rv0003
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionPhysicalInteraction Rv3715cactivejgalag2012-10-05

authors,N. Makharashvili,T. Mi,O. Koroleva,S. Korolev RecR-mediated modulation of RecF dimer specificity for single- and double-stranded DNA. J. Biol. Chem. 2009
InteractionRegulatory Rv3286cactiveshahanup862012-10-05
Co-expression (Functional linkage)
EP. Williams, JH. Lee et al. Mycobacterium tuberculosis SigF regulates genes encoding cell wall-associated proteins and directly regulates the transcriptional regulatory gene phoY1. J. Bacteriol. 2007
InteractionPhysicalInteraction Rv3715cactivesinghpankaj21162012-10-05

P. Singh, KN. Patil et al. Mycobacterium tuberculosis UvrD1 and UvrA Proteins Suppress DNA Strand Exchange Promoted by Cognate and Non-cognate RecA Proteins. Biochemistry 2010
InteractionPhysicalInteraction Rv2362cactivesinghpankaj21162012-10-05

P. Singh, KN. Patil et al. Mycobacterium tuberculosis UvrD1 and UvrA Proteins Suppress DNA Strand Exchange Promoted by Cognate and Non-cognate RecA Proteins. Biochemistry 2010
InteractionPhysicalInteraction Rv2737cactivesinghpankaj21162012-10-05

P. Singh, KN. Patil et al. Mycobacterium tuberculosis UvrD1 and UvrA Proteins Suppress DNA Strand Exchange Promoted by Cognate and Non-cognate RecA Proteins. Biochemistry 2010
InteractionPhysicalInteraction Rv3715cactivesinghpankaj21162012-10-05

authors,V. Mizrahi,SJ. Andersen DNA repair in Mycobacterium tuberculosis. What have we learnt from the genome sequence? Mol. Microbiol. 1998
InteractionPhysicalInteraction Rv2362cactivesinghpankaj21162012-10-05

authors,V. Mizrahi,SJ. Andersen DNA repair in Mycobacterium tuberculosis. What have we learnt from the genome sequence? Mol. Microbiol. 1998
InteractionPhysicalInteraction Rv2737cactivesinghpankaj21162012-10-05

authors,V. Mizrahi,SJ. Andersen DNA repair in Mycobacterium tuberculosis. What have we learnt from the genome sequence? Mol. Microbiol. 1998
InteractionRegulatedBy Rv2711activeyamir.moreno2012-10-05
Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support.
G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
InteractionRegulatedBy Rv1985cactiveyamir.moreno2012-10-05
E.coli orthology based inference. Orthologous pair regulator-target found in E.coli.
G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
InteractionRegulatedBy Rv0001activeyamir.moreno2012-10-05
E.coli orthology based inference. Orthologous pair regulator-target found in E.coli.
G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
InteractionRegulatedBy Rv3286cactiveyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
EP. Williams, JH. Lee et al. Mycobacterium tuberculosis SigF regulates genes encoding cell wall-associated proteins and directly regulates the transcriptional regulatory gene phoY1. J. Bacteriol. 2007
InteractionRegulatedBy Rv1985cactiveyamir.moreno2012-10-05
E.coli orthology based inference. Orthologous pair regulator-target found in E.coli.
authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006
InteractionRegulatedBy Rv0001activeyamir.moreno2012-10-05
E.coli orthology based inference. Orthologous pair regulator-target found in E.coli.
authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006
OtherTBPWY:Recombination repairactivevmizrahi2012-03-05
GenomeViewNEW neW_FEATURE = 42activepsisk2012-02-24
GenomeViewSTOP: 4437=>4443activepsisk2012-02-24