Rv0101 - peptide synthetase nrp


Protein Domains

Gene Information
LocusRv0101
Symbolnrp
Gene Namepeptide synthetase nrp
Location110001 - 117539 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:7539 bp
Protein:2513 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number30629
Related GenesML1996 MT0110 MUL_4858
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
Search for regulators of Rv0101
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionTranscription Rv0102activegaurisd102012-10-05
Coexpression
T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003
InteractionRegulatory Rv3911activegaurisd102012-10-05
Microarray Analysis
F. Wang, R. Langley et al. Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence. Chem. Biol. 2007
InteractionRegulatory Rv3911activegaurisd102012-10-05
Microarray Analysis
S. Raman, X. Puyang et al. Mycobacterium tuberculosis SigM positively regulates Esx secreted protein and nonribosomal peptide synthetase genes and down regulates virulence-associated surface lipid synthesis. J. Bacteriol. 2006
InteractionRegulatory Rv3911activegaurisd102012-10-05
Microarray Analysis
F. Wang, R. Langley et al. Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence. Chem. Biol. 2007
InteractionTranscription Rv0102activeashwinigbhat2012-10-05
Coexpression
J. King-Scott, E. Nowak et al. The structure of a full-length response regulator from Mycobacterium tuberculosis in a stabilized three-dimensional domain-swapped, activated state. J. Biol. Chem. 2007
InteractionTranscription Rv0100activeashwinigbhat2012-10-05
Coexpression
J. King-Scott, E. Nowak et al. The structure of a full-length response regulator from Mycobacterium tuberculosis in a stabilized three-dimensional domain-swapped, activated state. J. Biol. Chem. 2007
InteractionTranscription Rv0099activeashwinigbhat2012-10-05
Coexpression
J. King-Scott, E. Nowak et al. The structure of a full-length response regulator from Mycobacterium tuberculosis in a stabilized three-dimensional domain-swapped, activated state. J. Biol. Chem. 2007
InteractionTranscription Rv0098activeashwinigbhat2012-10-05
Coexpression
J. King-Scott, E. Nowak et al. The structure of a full-length response regulator from Mycobacterium tuberculosis in a stabilized three-dimensional domain-swapped, activated state. J. Biol. Chem. 2007
InteractionTranscription Rv0097activeashwinigbhat2012-10-05
Coexpression
J. King-Scott, E. Nowak et al. The structure of a full-length response regulator from Mycobacterium tuberculosis in a stabilized three-dimensional domain-swapped, activated state. J. Biol. Chem. 2007
InteractionTranscription Rv0096activeashwinigbhat2012-10-05
Coexpression
J. King-Scott, E. Nowak et al. The structure of a full-length response regulator from Mycobacterium tuberculosis in a stabilized three-dimensional domain-swapped, activated state. J. Biol. Chem. 2007
InteractionTranscription Rv0102activeashwinigbhat2012-10-05
Coexpression
F. Wang, R. Langley et al. Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence. Chem. Biol. 2007
InteractionTranscription Rv0100activeashwinigbhat2012-10-05
Coexpression
F. Wang, R. Langley et al. Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence. Chem. Biol. 2007
InteractionTranscription Rv0099activeashwinigbhat2012-10-05
Coexpression
F. Wang, R. Langley et al. Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence. Chem. Biol. 2007
InteractionTranscription Rv0098activeashwinigbhat2012-10-05
Coexpression
F. Wang, R. Langley et al. Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence. Chem. Biol. 2007
InteractionTranscription Rv0097activeashwinigbhat2012-10-05
Coexpression
F. Wang, R. Langley et al. Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence. Chem. Biol. 2007
InteractionTranscription Rv0096activeashwinigbhat2012-10-05
Coexpression
F. Wang, R. Langley et al. Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence. Chem. Biol. 2007
InteractionTranscription Rv0102activeashwinigbhat2012-10-05
Coexpression
T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003
InteractionTranscription Rv0100activeashwinigbhat2012-10-05
Coexpression
T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003
InteractionTranscription Rv0099activeashwinigbhat2012-10-05
Coexpression
T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003
InteractionTranscription Rv0098activeashwinigbhat2012-10-05
Coexpression
T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003
InteractionTranscription Rv0097activeashwinigbhat2012-10-05
Coexpression
T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003
InteractionTranscription Rv0096activeashwinigbhat2012-10-05
Coexpression
T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003
InteractionRegulatory Rv0491activeashwinigbhat2012-10-05
Microarray Analysis
F. Wang, R. Langley et al. Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence. Chem. Biol. 2007
InteractionRegulatory Rv0491activeashwinigbhat2012-10-05
Microarray Analysis
T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003
InteractionTranscription Rv0100activeashwinigbhat2012-10-05
Coexpression
J. King-Scott, E. Nowak et al. The structure of a full-length response regulator from Mycobacterium tuberculosis in a stabilized three-dimensional domain-swapped, activated state. J. Biol. Chem. 2007
InteractionTranscription Rv0100activeashwinigbhat2012-10-05
Coexpression
F. Wang, R. Langley et al. Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence. Chem. Biol. 2007
InteractionTranscription Rv0100activeashwinigbhat2012-10-05
Coexpression
T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003
InteractionTranscription Rv0099activeashwinigbhat2012-10-05
Coexpression
J. King-Scott, E. Nowak et al. The structure of a full-length response regulator from Mycobacterium tuberculosis in a stabilized three-dimensional domain-swapped, activated state. J. Biol. Chem. 2007
InteractionTranscription Rv0099activeashwinigbhat2012-10-05
Coexpression
F. Wang, R. Langley et al. Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence. Chem. Biol. 2007
InteractionTranscription Rv0099activeashwinigbhat2012-10-05
Coexpression
T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003
InteractionTranscription Rv0098activeashwinigbhat2012-10-05
Coexpression
J. King-Scott, E. Nowak et al. The structure of a full-length response regulator from Mycobacterium tuberculosis in a stabilized three-dimensional domain-swapped, activated state. J. Biol. Chem. 2007
InteractionTranscription Rv0098activeashwinigbhat2012-10-05
Coexpression
F. Wang, R. Langley et al. Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence. Chem. Biol. 2007
InteractionTranscription Rv0098activeashwinigbhat2012-10-05
Coexpression
T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003
InteractionTranscription Rv0097activeashwinigbhat2012-10-05
Coexpression
J. King-Scott, E. Nowak et al. The structure of a full-length response regulator from Mycobacterium tuberculosis in a stabilized three-dimensional domain-swapped, activated state. J. Biol. Chem. 2007
InteractionTranscription Rv0097activeashwinigbhat2012-10-05
Coexpression
F. Wang, R. Langley et al. Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence. Chem. Biol. 2007
InteractionTranscription Rv0097activeashwinigbhat2012-10-05
Coexpression
T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003
InteractionTranscription Rv0096activeashwinigbhat2012-10-05
Coexpression
J. King-Scott, E. Nowak et al. The structure of a full-length response regulator from Mycobacterium tuberculosis in a stabilized three-dimensional domain-swapped, activated state. J. Biol. Chem. 2007
InteractionTranscription Rv0096activeashwinigbhat2012-10-05
Coexpression
F. Wang, R. Langley et al. Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence. Chem. Biol. 2007
InteractionTranscription Rv0096activeashwinigbhat2012-10-05
Coexpression
T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003
InteractionRegulatedBy Rv0491activeyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003