Rv0126 - trehalose synthase treS

Expression: Most Significant Conditions for Rv0126

Protein Domains

Gene Information
Locus	Rv0126
Symbol	treS
Gene Name	trehalose synthase treS
Location	152324 - 154129 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1806 bp Protein:602 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	34239
Related Genes	Acel_0678 MAP3528 MAV_5186 Mkms_5210 Mmcs_5121 MSMEG_6515 MT0134 MUL_4797 PPA1113 SAV2803
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0126
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0126 Transcript 1
MNEAEHSVEHPPVQGSHVEGGVVEHPDAKDFGSAAALPADPTWFKHAVFYEVLVRAFFDA
SADGSGDLRGLIDRLDYLQWLGIDCIWLPPFYDSPLRDGGYDIRDFYKVLPEFGTVDDFV
ALVDAAHRRGIRIITDLVMNHTSESHPWFQESRRDPDGPYGDYYVWSDTSERYTDARIIF
VDTEESNWSFDPVRRQFYWHRFFSHQPDLNYDNPAVQEAMIDVIRFWLGLGIDGFRLDAV
PYLFEREGTNCENLPETHAFLKRVRKVVDDEFPGRVLLAEANQWPGDVVEYFGDPNTGGD
ECHMAFHFPLMPRIFMAVRRESRFPISEIIAQTPPIPDMAQWGIFLRNHDELTLEMVTDE
ERDYMYAEYAKDPRMKANVGIRRRLAPLLDNDRNQIELFTALLLSLPGSPVLYYGDEIGM
GDVIWLGDRDGVRIPMQWTPDRNAGFSTANPGRLYLPPSQDPVYGYQAVNVEAQRDTSTS
LLNFTRTMLAVRRRHPAFAVGAFQELGGSNPSVLAYVRQVAGDDGDTVLCVNNLSRFPQP
IELDLQQWTNYTPVELTGHVEFPRIGQVPYLLTLPGHGFYWFQLTTHEVGAPPTCGGERR
L*

Genomic Sequence

>Rv0126
ATGAACGAGGCAGAACACAGCGTCGAGCACCCTCCCGTGCAGGGCAGTCACGTCGAAGGC
GGTGTGGTCGAGCATCCGGATGCCAAGGACTTCGGCAGCGCCGCCGCCCTGCCCGCCGAT
CCGACCTGGTTTAAGCACGCCGTCTTCTACGAGGTGCTGGTCCGGGCGTTCTTCGACGCC
AGCGCGGACGGTTCCGGCGATCTGCGTGGACTCATCGATCGCCTCGACTACCTGCAGTGG
CTTGGCATCGACTGCATCTGGTTGCCGCCGTTCTACGACTCGCCGCTGCGCGACGGCGGT
TACGACATTCGCGACTTCTACAAGGTGCTGCCCGAATTCGGCACCGTCGACGATTTCGTC
GCCCTGGTCGACGCCGCTCACCGGCGAGGTATCCGCATCATCACCGACCTGGTGATGAAT
CACACCTCGGAGTCGCACCCCTGGTTTCAGGAGTCCCGCCGCGACCCAGACGGACCGTAC
GGTGACTATTACGTGTGGAGCGACACCAGCGAGCGCTACACCGACGCCCGGATCATCTTC
GTCGACACCGAAGAGTCGAACTGGTCATTCGATCCTGTCCGCCGACAGTTCTACTGGCAC
CGATTCTTCTCCCACCAACCGGATCTGAACTACGACAACCCCGCCGTGCAAGAGGCGATG
ATCGACGTCATCCGCTTTTGGCTCGGCTTGGGCATCGACGGGTTTCGGTTGGACGCGGTG
CCCTATCTCTTTGAACGTGAGGGCACCAACTGCGAGAACCTGCCGGAAACACACGCTTTT
CTCAAGCGAGTCCGCAAGGTGGTGGACGACGAATTCCCCGGCCGGGTGCTGCTAGCCGAA
GCCAATCAGTGGCCGGGCGATGTCGTCGAATATTTCGGTGATCCCAACACCGGTGGCGAC
GAGTGCCACATGGCCTTTCACTTCCCGCTGATGCCGCGCATCTTCATGGCCGTGCGCCGG
GAGTCCCGTTTTCCGATCTCGGAGATCATCGCCCAGACCCCACCAATCCCTGACATGGCG
CAATGGGGGATATTTCTGCGCAACCACGACGAGCTGACGTTAGAAATGGTCACCGACGAA
GAGCGCGACTACATGTACGCCGAGTACGCCAAGGATCCACGGATGAAGGCGAATGTCGGA
ATCCGTCGTCGGCTTGCGCCGCTGCTCGACAACGACCGCAACCAGATCGAGCTGTTCACC
GCGCTGCTGCTGTCGCTGCCCGGCTCGCCGGTCCTCTACTACGGCGACGAGATCGGGATG
GGCGACGTGATCTGGTTGGGTGATCGCGACGGCGTGCGCATCCCGATGCAGTGGACACCG
GACCGCAACGCGGGTTTCTCCACCGCCAACCCGGGTCGGCTGTACCTGCCGCCCAGCCAG
GACCCGGTTTACGGGTATCAGGCCGTCAACGTCGAGGCGCAACGCGACACCTCGACGTCG
CTGCTCAACTTCACTCGCACCATGCTGGCCGTGCGTCGCCGACACCCCGCGTTTGCGGTC
GGCGCATTCCAGGAATTGGGCGGGTCCAACCCGTCGGTGCTGGCCTACGTGCGTCAGGTG
GCCGGCGATGACGGCGACACCGTGCTCTGTGTCAACAACCTGTCGCGATTCCCGCAGCCC
ATCGAATTGGACTTGCAGCAATGGACCAACTACACGCCGGTCGAGCTGACCGGGCACGTG
GAGTTTCCACGCATCGGCCAGGTGCCCTATCTGCTGACGCTGCCAGGACACGGGTTCTAC
TGGTTCCAGTTGACCACACATGAGGTGGGGGCACCTCCCACTTGCGGGGGAGAGCGGCGC
CTATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Name	Trehalose synthase; displays maltose <--> trehalose interconverting activity and glycogen amylase activity	active	mjackson	2012-10-05
	Other (lipo)polysaccharides [Methylglucose lipolysaccharides, glycogen and capsular alpha-1,4 glucan]
Name	Trehalose synthase; displays maltose <--> trehalose interconverting activity and glycogen amylase activity	active	mjackson	2012-10-05
	Other (lipo)polysaccharides [Methylglucose lipolysaccharides, glycogen and capsular alpha-1,4 glucan]
Name	TREHALOSE SYNTHASE: INVOLVED IN TREHALOSE BIOSYNTHESIS FROM MALTOSE	active	mjackson	2012-10-05
	Trehalose biosynthesis
Symbol	TreS	active	mjackson	2012-10-05
	Trehalose biosynthesis
Name	TREHALOSE SYNTHASE: INVOLVED IN TREHALOSE BIOSYNTHESIS FROM MALTOSE	active	mjackson	2012-10-05
	Trehalose biosynthesis
Symbol	TreS	active	mjackson	2012-10-05
	Trehalose biosynthesis
Other	TBPWY:(MGLP and alpha-1,4 glucans)	active	mjackson	2012-03-05
	Trehalose synthase; displays maltose <--> trehalose interconverting activity and glycogen amylase activity (phenotypic [mycobacterial recombinant strains]; enzymatic) R. Kalscheuer,K. Syson,U. Veeraraghavan,B. Weinrick,KE. Biermann,Z. Liu,JC. Sacchettini,G. Besra,S. Bornemann,WR. Jacobs Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an alpha-glucan pathway. Nature chemical biology 2010
Other	TBPWY:(MGLP and alpha-1,4 glucans)	active	mjackson	2012-03-05
	Trehalose synthase; displays maltose <--> trehalose interconverting activity and glycogen amylase activity (phenotypic [mycobacterial recombinant strains]; enzymatic) YT. Pan, JD. Carroll et al. Trehalose synthase converts glycogen to trehalose. FEBS J. 2008
Other	TBPWY:(MGLP and alpha-1,4 glucans)	active	mjackson	2012-03-05
	Trehalose synthase; displays maltose <--> trehalose interconverting activity and glycogen amylase activity (phenotypic [mycobacterial recombinant strains]; enzymatic) authors,YT. Pan,V. Koroth Edavana,WJ. Jourdian,R. Edmondson,JD. Carroll,I. Pastuszak,AD. Elbein Trehalose synthase of Mycobacterium smegmatis: purification, cloning, expression, and properties of the enzyme. Eur. J. Biochem. 2004
Other	TBPWY:(MGLP and alpha-1,4 glucans)	active	mjackson	2012-03-05
	Trehalose synthase; displays maltose <--> trehalose interconverting activity and glycogen amylase activity (phenotypic [mycobacterial recombinant strains]; enzymatic) KA. De Smet, A. Weston et al. Three pathways for trehalose biosynthesis in mycobacteria. Microbiology (Reading, Engl.) 2000