Rv0189c - dihydroxy-acid dehydratase ilvD

Expression: Most Significant Conditions for Rv0189c

Protein Domains

Gene Information
Locus	Rv0189c
Symbol	ilvD
Gene Name	dihydroxy-acid dehydratase ilvD
Location	219996 - 221723 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1728 bp Protein:576 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	33282
Related Genes	CE2439 MAP3631c MAV_4989 Mkms_0155 ML2608 Mmcs_0146 MSMEG_0229 MT0199 MUL_1082 Mvan_0173 nfa11740
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0189c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0189c Transcript 1
MPQTTDEAASVSTVADIKPRSRDVTDGLEKAAARGMLRAVGMDDEDFAKPQIGVASSWNE
ITPCNLSLDRLANAVKEGVFSAGGYPLEFGTISVSDGISMGHEGMHFSLVSREVIADSVE
VVMQAERLDGSVLLAGCDKSLPGMLMAAARLDLAAVFLYAGSILPGRAKLSDGSERDVTI
IDAFEAVGACSRGLMSRADVDAIERAICPGEGACGGMYTANTMASAAEALGMSLPGSAAP
PATDRRRDGFARRSGQAVVELLRRGITARDILTKEAFENAIAVVMAFGGSTNAVLHLLAI
AHEANVALSLQDFSRIGSGVPHLADVKPFGRHVMSDVDHIGGVPVVMKALLDAGLLHGDC
LTVTGHTMAENLAAITPPDPDGKVLRALANPIHPSGGITILHGSLAPEGAVVKTAGFDSD
VFEGTARVFDGERAALDALEDGTITVGDAVVIRYEGPKGGPGMREMLAITGAIKGAGLGK
DVLLLTDGRFSGGTTGLCVGHIAPEAVDGGPIALLRNGDRIRLDVAGRVLDVLADPAEFA
SRQQDFSPPPPRYTTGVLSKYVKLVSSAAVGAVCG*

Genomic Sequence

>Rv0189c
ATGCCGCAAACCACCGACGAAGCCGCTTCCGTCTCGACGGTCGCCGACATCAAGCCCCGC
AGTCGAGACGTCACCGACGGCCTGGAGAAGGCCGCTGCCCGGGGCATGTTGAGGGCGGTG
GGCATGGACGACGAAGACTTCGCGAAGCCACAGATCGGGGTCGCGTCGTCGTGGAACGAA
ATCACGCCGTGCAATCTCTCATTGGACCGGCTGGCCAACGCGGTCAAGGAGGGGGTGTTT
TCGGCCGGCGGCTATCCGCTTGAGTTCGGCACGATCTCGGTTTCGGACGGCATCTCCATG
GGTCATGAGGGGATGCACTTCTCGCTGGTTTCCCGTGAGGTGATCGCCGACAGCGTCGAA
GTCGTGATGCAGGCCGAACGACTCGACGGTTCGGTGCTGCTGGCCGGATGCGACAAATCG
CTGCCCGGAATGCTGATGGCCGCCGCACGACTGGATCTGGCGGCGGTGTTCCTCTACGCG
GGCTCTATTTTGCCCGGCCGGGCCAAGCTCTCCGACGGTAGCGAACGAGACGTCACCATC
ATTGACGCCTTCGAGGCGGTCGGAGCGTGCTCTCGCGGTTTGATGAGTCGCGCCGACGTC
GATGCCATCGAGCGGGCAATCTGCCCCGGCGAAGGGGCATGCGGCGGCATGTACACCGCT
AACACCATGGCCAGCGCCGCCGAGGCGCTCGGCATGTCGTTGCCGGGCAGCGCGGCACCG
CCGGCGACCGACCGCCGGCGCGACGGGTTCGCGCGTCGCAGCGGTCAGGCCGTCGTCGAG
CTGCTGCGCCGCGGCATCACCGCCCGCGACATCCTCACCAAGGAGGCGTTCGAGAACGCC
ATCGCGGTGGTAATGGCGTTCGGCGGCTCGACCAACGCGGTGCTGCATCTGCTGGCCATC
GCCCACGAGGCCAACGTCGCACTATCGCTTCAGGACTTCAGCCGGATCGGGTCGGGGGTG
CCGCATTTGGCCGATGTCAAGCCGTTCGGCCGCCATGTGATGTCCGACGTCGATCACATC
GGCGGTGTGCCGGTGGTTATGAAGGCGCTGCTGGACGCCGGTCTGCTACACGGCGACTGC
CTGACGGTTACCGGTCACACCATGGCCGAGAATCTGGCTGCCATCACCCCGCCGGATCCA
GATGGCAAGGTGCTACGTGCGTTGGCAAACCCGATCCACCCGAGCGGTGGCATCACCATC
CTGCACGGATCGCTGGCACCCGAAGGTGCGGTGGTCAAGACCGCCGGATTCGATTCCGAC
GTATTCGAAGGCACCGCAAGAGTTTTCGACGGCGAGCGCGCTGCGCTGGACGCCCTTGAG
GATGGCACCATTACCGTGGGCGACGCCGTGGTAATCCGGTACGAAGGACCCAAGGGCGGC
CCCGGGATGCGCGAAATGCTCGCCATCACAGGCGCGATCAAAGGCGCAGGACTCGGTAAA
GATGTTCTACTGCTGACCGACGGCCGGTTCTCCGGTGGAACCACCGGCCTGTGCGTTGGC
CACATCGCACCGGAGGCGGTCGACGGCGGACCGATCGCACTTCTGCGCAACGGCGACCGG
ATCCGGCTCGACGTGGCCGGCCGCGTTCTCGATGTGTTGGCCGATCCGGCCGAATTCGCG
TCCCGACAACAGGATTTCAGTCCTCCACCGCCGCGCTACACTACTGGCGTACTGTCCAAG
TACGTCAAGCTGGTCAGCTCTGCCGCGGTCGGCGCGGTCTGCGGCTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv3291c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv3291c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006