Rv0242c - 3-oxoacyl-[acyl-carrier protein] reductase fabG4

Expression: Most Significant Conditions for Rv0242c

Protein Domains

Gene Information
Locus	Rv0242c
Symbol	fabG
Gene Name	3-oxoacyl-[acyl-carrier protein] reductase fabG4
Location	290665 - 292029 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1365 bp Protein:455 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	36661
Related Genes	CE0913 cg0957 jk0821 jk0822 MAP3691c MAP3692c MAV_4916 MAV_4917 Mkms_0249 Mkms_0250 ML2565 ML2566 Mmcs_0239 Mmcs_0240 MSMEG_0371 MSMEG_0372 MT0255 MT0256 MUL_1165 MUL_1166 Mvan_0258 Mvan_0259 Mvan_0262 nfa54610 nfa54620 PPA1813 PPA1815 PPA1817 Rv0241c
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0242c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0242c Transcript 1
MAPKRSSDLFSQVVNSGPGSFLARQLGVPQPETLRRYRAGEPPLTGSLLIGGAGRVVEPL
RAALEKDYDLVGNNLGGRWADSFGGLVFDATGITEPAGLKGLHEFFTPVLRNLGRCGRVV
VVGGTPEAAASTNERIAQRALEGFTRSLGKELRRGATTALVYLSPDAKPAATGLESTMRF
LLSAKSAYVDGQVFSVGADDSTPPADWEKPLDGKVAIVTGAARGIGATIAEVFARDGAHV
VAIDVESAAENLAETASKVGGTALWLDVTADDAVDKISEHLRDHHGGKADILVNNAGITR
DKLLANMDDARWDAVLAVNLLAPLRLTEGLVGNGSIGEGGRVIGLSSIAGIAGNRGQTNY
ATTKAGMIGITQALAPGLAAKGITINAVAPGFIETQMTAAIPLATREVGRRLNSLLQGGQ
PVDVAEAIAYFASPASNAVTGNVIRVCGQAMIGA*

Genomic Sequence

>Rv0242c
GTGGCTCCCAAGCGTTCGTCCGATCTGTTCTCGCAGGTTGTCAACTCCGGTCCAGGATCG
TTTTTGGCCAGGCAATTGGGTGTTCCGCAACCCGAGACGCTTCGCCGCTATCGAGCAGGC
GAACCGCCACTGACCGGGTCGCTGCTGATCGGCGGGGCCGGCAGGGTCGTCGAACCACTG
CGCGCGGCACTCGAAAAGGACTACGACCTGGTAGGAAACAACCTGGGCGGGCGCTGGGCG
GACTCGTTCGGCGGGCTGGTCTTCGACGCCACCGGCATCACAGAGCCGGCCGGGCTCAAG
GGGCTGCACGAGTTCTTTACTCCGGTACTGCGCAATCTCGGCCGTTGCGGGCGCGTGGTG
GTTGTTGGCGGCACACCCGAAGCGGCCGCCAGCACGAACGAGCGGATCGCGCAGCGCGCG
CTGGAGGGCTTCACCCGCTCGCTGGGCAAGGAACTGCGCCGCGGTGCGACAACGGCGTTG
GTCTACCTGTCGCCGGACGCCAAGCCCGCAGCTACCGGCCTCGAGTCGACCATGCGATTC
CTGCTGTCGGCCAAGTCGGCCTACGTCGACGGCCAAGTCTTCTCTGTCGGGGCGGACGAT
TCCACACCGCCGGCCGACTGGGAGAAGCCGCTGGACGGCAAGGTCGCCATTGTGACCGGC
GCGGCCCGCGGCATCGGCGCAACCATCGCCGAGGTGTTCGCTCGCGACGGCGCCCACGTG
GTCGCCATCGATGTGGAGTCCGCCGCCGAGAACCTGGCCGAAACCGCCAGCAAGGTGGGC
GGCACCGCGCTGTGGCTCGACGTCACCGCCGACGATGCCGTCGACAAGATCAGCGAGCAC
CTGCGCGACCACCACGGTGGCAAGGCCGACATCCTGGTCAACAACGCCGGCATCACCCGT
GACAAGCTGCTGGCCAACATGGACGATGCGCGTTGGGACGCCGTCCTGGCTGTCAATCTG
CTTGCCCCGTTGCGGCTCACCGAGGGTCTGGTGGGCAACGGCAGCATCGGAGAGGGTGGT
CGGGTGATCGGGCTGTCGTCGATCGCCGGCATCGCCGGCAACCGCGGCCAGACCAACTAC
GCCACCACCAAGGCCGGGATGATCGGCATCACCCAGGCGCTGGCACCCGGCCTGGCCGCG
AAAGGCATCACGATCAACGCCGTGGCACCGGGATTCATCGAAACCCAGATGACGGCCGCC
ATCCCGCTGGCCACCCGTGAGGTAGGCCGCCGGCTGAACTCGCTGCTGCAGGGCGGGCAG
CCCGTCGACGTCGCCGAGGCCATCGCCTACTTCGCCAGCCCGGCGTCAAACGCGGTGACC
GGCAACGTCATTCGTGTCTGCGGCCAGGCCATGATCGGCGCGTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Name	-Ketoacyl-ACP reductase/3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE	active	mjackson	2012-10-05
	FAS-II
Symbol	fabG4	active	mjackson	2012-10-05
	FAS-II
Term	EC:1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay K. Takayama, C. Wang et al. Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis. Clin. Microbiol. Rev. 2005
Term	EC:2.3.1.41 Beta-ketoacyl-acyl-carrier-protein synthase I. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay K. Takayama, C. Wang et al. Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis. Clin. Microbiol. Rev. 2005
Term	EC:2.1.1.- Transferases. Transferring one-carbon groups. Methyltransferases. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay K. Takayama, C. Wang et al. Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis. Clin. Microbiol. Rev. 2005