Rv0338c - iron-sulfur-binding reductase

Expression: Most Significant Conditions for Rv0338c

Protein Domains

Gene Information
Locus	Rv0338c
Symbol
Gene Name	iron-sulfur-binding reductase
Location	403193 - 405841 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:2649 bp Protein:883 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	27116
Related Genes	MAP3831c MAV_4817 Mkms_0452 ML2501 Mmcs_0442 MSMEG_0690 MT0352 MUL_0574 Mvan_0619 nfa54200
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0338c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0338c Transcript 1
MTTQTLIRLILGMSMTAVVGVFALRRVWWLYKLVMSGQPASGRTDNLGTRIWTQISEVLG
QRRLLKWSIPGLAHFFTMWGFFILLTVYIEAYGLLFEERFHIPVIGRWDALGFLQDFFAT
AVFLGITTFAIIRILRNPREIGRSSRFYGSHNGGAWLVLLMIFNVIWTYVLVRGSAVNNG
TLPYGNGAFLSQLFGAILRPLGQPANEIIETTALLLHIGVMLAFLILVLHSKHLHIFLAP
INVTFKRLPDGLGPLLPLEADGKPIDFENPSEDAVFGRGKIEDFTWKGMLDFATCTECGR
CQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGQKDASAGGEAGHQEHHHVPESGFG
RVPGHGPEQATRPLVGTEEQGGVIDPDVLWSCVTCGACVEQCPVDIEHVDHIVDMRRYQV
MMESEFPSELSVLFKNLETKGNPWGQNASDRTNWIDEVDFDVPVYGQDVDSFDGYEYLFW
VGCAGAYDDKAKKTTKAVAELLAVARVKYLVLGAGETCNGDSARRSGNEFLFQQLAQQAV
ETLDGLFEGVETVDRKIVVTCPHCFNTIGKEYRQLGANYTVLHHTQLLNRLVRDKRLVPV
TPVSQDITYHDPCYLGRHNKAYEAPRELIGAAGASLTEMPRHADRSFCCGAGGARMWMEE
HIGKRINHERVDEALATDATAIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLG
SLDHDKAQLPAKGTAAKQAQERAPKAAPKAAAPVTPVEAPAEAPQAPAPAAPAAPVKGLG
MAAGAKRPGAKKAAPTPAAPAAPAAPVKGLGIAAGAKRPGAKKTPPPAPGLAEPAAQPQP
EAKPQPEPAAPPKPQTDGDPAAPAAPVKGLGIARGARPPGKR*

Genomic Sequence

>Rv0338c
GTGACCACGCAAACGCTCATCAGGCTGATACTGGGCATGAGCATGACCGCGGTGGTGGGG
GTGTTCGCTCTGCGGCGAGTCTGGTGGCTTTACAAGCTGGTCATGTCCGGGCAGCCGGCC
AGCGGGCGAACCGACAACCTCGGCACCCGCATCTGGACCCAGATCTCCGAGGTTCTAGGG
CAGCGCCGACTGTTGAAATGGTCGATCCCGGGCCTGGCGCACTTTTTCACCATGTGGGGC
TTCTTCATCCTGCTCACCGTCTATATCGAGGCTTACGGCCTGCTGTTCGAGGAGAGATTC
CACATCCCGGTCATCGGCCGGTGGGACGCGTTGGGCTTCCTGCAGGACTTCTTTGCCACC
GCCGTCTTTCTCGGTATCACGACCTTCGCCATCATCCGTATCCTGCGCAACCCCCGCGAG
ATCGGTCGGAGCTCCCGGTTCTACGGATCGCACAACGGCGGCGCGTGGCTCGTCCTGTTG
ATGATCTTCAACGTCATCTGGACCTACGTGTTGGTCCGCGGCTCAGCGGTCAACAACGGC
ACCCTGCCCTACGGCAACGGGGCCTTCCTATCGCAGCTATTCGGCGCGATTCTTCGCCCC
CTCGGGCAGCCCGCCAACGAAATCATCGAAACCACAGCGCTGTTGCTGCACATCGGGGTC
ATGCTTGCGTTCCTGATCCTCGTTTTGCATTCCAAGCACCTGCACATCTTCCTGGCGCCC
ATTAACGTCACGTTCAAACGGCTGCCGGATGGGCTGGGCCCGCTGTTGCCGCTCGAAGCC
GATGGCAAACCAATCGACTTCGAGAATCCCAGCGAGGATGCCGTATTCGGCCGCGGCAAG
ATCGAAGACTTCACCTGGAAGGGGATGCTCGACTTCGCTACCTGCACCGAGTGCGGACGC
TGTCAGTCGCAATGCCCGGCCTGGAACACCGGCAAACCGTTGTCGCCCAAGCTGGTCATC
ATGGACCTGCGCGACCATTGGATGGCCAAGGCGCCCTACATCCTGGGCCAAAAGGATGCC
AGCGCGGGCGGCGAGGCCGGTCACCAAGAGCATCATCACGTGCCGGAATCGGGGTTCGGT
CGAGTGCCCGGGCATGGACCGGAGCAGGCGACTCGCCCGCTGGTCGGCACCGAGGAACAG
GGTGGCGTTATCGATCCCGACGTCTTGTGGTCATGTGTGACCTGTGGTGCCTGCGTCGAG
CAGTGCCCGGTGGATATCGAACATGTCGATCACATCGTCGATATGCGCCGCTACCAGGTG
ATGATGGAGTCGGAGTTCCCCTCCGAGCTGTCGGTGCTGTTCAAGAACCTGGAGACCAAG
GGCAACCCGTGGGGTCAGAACGCCTCAGATCGCACCAACTGGATCGACGAGGTTGACTTC
GACGTCCCCGTGTACGGCCAGGACGTCGACAGCTTCGACGGCTACGAGTACCTGTTCTGG
GTGGGTTGTGCGGGCGCCTACGACGACAAGGCCAAGAAGACCACCAAGGCCGTCGCCGAG
CTGCTCGCCGTCGCCAGGGTGAAATACTTGGTGCTGGGCGCTGGGGAAACCTGCAACGGC
GACTCGGCGCGCCGCTCCGGCAACGAGTTCCTCTTCCAGCAGCTGGCACAACAGGCCGTC
GAGACCCTGGACGGTTTGTTCGAGGGTGTGGAGACCGTCGACCGCAAGATCGTTGTCACC
TGCCCGCACTGCTTCAACACCATCGGCAAGGAATATCGGCAGCTGGGCGCCAACTACACC
GTGCTGCACCACACCCAGCTGCTCAATCGGTTGGTGCGCGACAAGAGGCTGGTCCCTGTC
ACTCCGGTTTCTCAGGACATCACCTACCACGACCCGTGCTACCTGGGTCGGCACAACAAG
GCCTACGAGGCACCACGGGAGCTGATCGGTGCCGCGGGGGCCAGCCTGACCGAGATGCCG
CGCCATGCCGACCGCAGCTTTTGTTGCGGCGCAGGCGGCGCCCGCATGTGGATGGAAGAA
CACATCGGCAAGCGGATCAACCATGAACGCGTCGATGAGGCGCTGGCCACCGATGCCACC
GCAATCGCCACCGCGTGCCCATTCTGCCGGGTGATGGTCACCGACGGTGTGAACGATCGG
CAGGAAGAAGCCGGCCGCAGCGGCGTCGAGGTGCTCGACGTGGCCCAGGTGCTACTCGGA
TCACTAGACCACGACAAGGCGCAGCTGCCGGCCAAGGGTACGGCCGCCAAACAGGCTCAG
GAGCGCGCCCCGAAAGCCGCTCCTAAGGCTGCCGCACCGGTGACGCCCGTGGAGGCACCC
GCCGAGGCACCACAGGCGCCAGCGCCGGCCGCTCCCGCAGCACCCGTGAAAGGCCTCGGC
ATGGCCGCCGGCGCCAAGCGGCCTGGCGCCAAGAAAGCGGCCCCAACGCCCGCGGCCCCG
GCTGCGCCCGCCGCGCCCGTTAAAGGGCTGGGTATTGCCGCCGGCGCCAAGCGGCCCGGG
GCGAAAAAGACACCTCCCCCGGCTCCTGGGCTCGCCGAGCCAGCAGCCCAGCCGCAACCC
GAAGCAAAGCCGCAACCGGAGCCCGCCGCACCGCCAAAGCCGCAAACCGACGGTGATCCG
GCTGCACCGGCCGCGCCGGTGAAAGGGCTGGGCATTGCGCGCGGGGCCCGTCCACCGGGC
AAACGCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv2711	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv2711	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. GM. Rodriguez, MI. Voskuil et al. ideR, An essential gene in mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response. Infect. Immun. 2002