Rv0534c - 1,4-dihydroxy-2-naphthoate octaprenyltransferase menA

Expression: Most Significant Conditions for Rv0534c

Protein Domains

Gene Information
Locus	Rv0534c
Symbol	menA
Gene Name	1,4-dihydroxy-2-naphthoate octaprenyltransferase menA
Location	625562 - 626440 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:879 bp Protein:293 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	18777
Related Genes	Acel_0150 BL1655 CE0469 cg0531 DIP0418 jk1877 MAP4029c MAV_4611 Mkms_0716 ML2406 Mmcs_0702 MSMEG_0988 MT0558 MUL_0633 Mvan_0880 nfa51470 PPA1945
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0534c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0534c Transcript 1
MASFAQWVSGARPRTLPNAIAPVVAGTGAAAWLHAAVWWKALLALAVAVALVIGVNYAND
YSDGIRGTDDDRVGPVRLVGSRLATPRSVLTAAMTSLALGALAGLVLALLSAPWLIAVGA
ICIAGAWLYTGGSKPYGYAGFGELAVFVFFGPVAVLGTQYTQALRVDWVGLAQAVATGAL
SCSVLVANNLRDIPTDARADKITLAVRLGDARTRMLYQGLLAVAGVLTFVLMLATPWCVV
GLVAAPLALRAAGPVRSGRGGRELIPVLRDTGLAMLVWALAVAGALAFGQLS*

Genomic Sequence

>Rv0534c
GTGGCCAGTTTCGCACAGTGGGTCTCCGGCGCGCGGCCCCGAACGCTGCCGAACGCGATC
GCGCCAGTGGTTGCCGGCACCGGCGCCGCGGCCTGGCTGCACGCGGCCGTGTGGTGGAAA
GCGCTGTTGGCACTGGCTGTTGCGGTGGCGCTGGTCATTGGGGTCAATTACGCCAATGAC
TACTCCGACGGCATCCGCGGCACCGATGACGACAGGGTGGGTCCGGTGCGGTTGGTGGGC
TCGCGGCTGGCGACCCCGCGCTCGGTGCTGACCGCTGCCATGACGAGCCTGGCGCTCGGT
GCGCTGGCCGGGCTGGTTTTGGCGCTGCTCAGCGCGCCGTGGCTGATTGCGGTGGGTGCG
ATCTGCATCGCCGGGGCCTGGCTCTACACCGGCGGGTCAAAACCCTACGGCTATGCGGGC
TTCGGCGAACTGGCGGTGTTTGTGTTCTTCGGGCCGGTCGCCGTGCTCGGTACCCAGTAC
ACGCAGGCATTGCGGGTGGACTGGGTGGGGCTGGCACAGGCGGTAGCAACGGGTGCGTTG
TCGTGCTCGGTGCTGGTGGCCAACAACCTGCGCGACATCCCCACCGACGCGCGGGCCGAC
AAGATCACGCTGGCGGTGCGGCTGGGAGACGCCCGGACCCGGATGCTTTACCAGGGCCTG
CTGGCGGTCGCCGGGGTGCTGACGTTCGTGCTAATGCTGGCCACGCCGTGGTGTGTGGTG
GGCTTGGTGGCCGCGCCTTTGGCGCTGCGCGCTGCCGGACCGGTGCGATCCGGGCGCGGC
GGGCGCGAGCTGATCCCGGTACTGCGTGACACTGGGCTGGCCATGCTGGTGTGGGCGTTG
GCGGTGGCGGGGGCATTGGCGTTTGGTCAGTTGAGCTAA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Term	TBRXN:DHNAOT 1,4-dihydroxy-2-naphthoate octaprenyltransferase - IPI	active	njamshidi	2012-10-05
	see PMID: 16131752, 12909628 JJ. Truglio, K. Theis et al. Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis. J. Biol. Chem. 2003
Term	TBRXN:DHNAOT 1,4-dihydroxy-2-naphthoate octaprenyltransferase - IPI	active	njamshidi	2012-10-05
	see PMID: 16131752, 12909628 JM. Johnston, VL. Arcus et al. Structure of naphthoate synthase (MenB) from Mycobacterium tuberculosis in both native and product-bound forms. Acta Crystallogr. D Biol. Crystallogr. 2005
Term	TBRXN:DHNAOT 1,4-dihydroxy-2-naphthoate octaprenyltransferase - ISS	active	njamshidi	2012-10-05
	see PMID: 16131752, 12909628 JJ. Truglio, K. Theis et al. Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis. J. Biol. Chem. 2003
Term	TBRXN:DHNAOT 1,4-dihydroxy-2-naphthoate octaprenyltransferase - ISS	active	njamshidi	2012-10-05
	see PMID: 16131752, 12909628 JM. Johnston, VL. Arcus et al. Structure of naphthoate synthase (MenB) from Mycobacterium tuberculosis in both native and product-bound forms. Acta Crystallogr. D Biol. Crystallogr. 2005