Rv0570 - ribonucleoside-diphosphate reductase large subunit nrdZ
Protein Domains

Gene Information
LocusRv0570
SymbolnrdZ
Gene Nameribonucleoside-diphosphate reductase large subunit nrdZ
Location661295 - 663373 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:2079 bp
Protein:693 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number32765
Related GenesAcel_1476 Mkms_1102 Mmcs_1085 MT0596 Mvan_1398 PPA1026 SAV2461 SCO5805
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
Search for regulators of Rv0570
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionRegulatory Rv3133cactivesourish102012-10-05
PCR
authors,J. Nurbo,AK. Roos,D. Muthas,E. Wahlström,DJ. Ericsson,T. Lundstedt,T. Unge,A. Karlén Design, synthesis and evaluation of peptide inhibitors of Mycobacterium tuberculosis ribonucleotide reductase. J. Pept. Sci. 2007
InteractionRegulatory Rv3133cactivesourish102012-10-05
PCR
SS. Dawes, DF. Warner et al. Ribonucleotide reduction in Mycobacterium tuberculosis: function and expression of genes encoding class Ib and class II ribonucleotide reductases. Infect. Immun. 2003
InteractionRegulatory Rv3133cactiveahal47892012-10-05
PCR
authors,J. Nurbo,AK. Roos,D. Muthas,E. Wahlström,DJ. Ericsson,T. Lundstedt,T. Unge,A. Karlén Design, synthesis and evaluation of peptide inhibitors of Mycobacterium tuberculosis ribonucleotide reductase. J. Pept. Sci. 2007
InteractionRegulatory Rv3133cactiveahal47892012-10-05
PCR
SS. Dawes, DF. Warner et al. Ribonucleotide reduction in Mycobacterium tuberculosis: function and expression of genes encoding class Ib and class II ribonucleotide reductases. Infect. Immun. 2003
InteractionRegulatedBy Rv0348activeyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
B. Abomoelak, EA. Hoye et al. mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2009
InteractionRegulatedBy Rv0981activeyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
H. He, R. Hovey et al. MprAB is a stress-responsive two-component system that directly regulates expression of sigma factors SigB and SigE in Mycobacterium tuberculosis. J. Bacteriol. 2006
InteractionRegulatedBy Rv3133cactiveyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
HD. Park, KM. Guinn et al. Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis. Mol. Microbiol. 2003