Rv0649 - malonyl CoA-acyl carrier protein transacylase fabD2

Expression: Most Significant Conditions for Rv0649

Protein Domains

Gene Information
Locus	Rv0649
Symbol	fabD2
Gene Name	malonyl CoA-acyl carrier protein transacylase fabD2
Location	746363 - 747037 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:675 bp Protein:225 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	6423
Related Genes	MAP4122 MAV_4511 Mkms_0982 Mmcs_0964 MSMEG_1362 MT0677 MUL_0738 Mvan_1250
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0649
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0649 Transcript 1
MSGRSRLPGSSSRRDAARIVAERVVATVAGVAVAVDEVDAAEARLRDGPRAAALPASGTS
EGRQLRRWLTQLIVTERVVAAEAAARGLTAAGAPAEADLLPDATARLEIGSVAAAVLADP
LARALFAAVTARVAVTDDAVADYHARNPLRFAAPCPGQHGWRAPAAAAPPLDQVRRAITE
HLLGAARRRAFRVWLDARRNALVVLAPGYEHPGDPRQPDNTRRH*

Genomic Sequence

>Rv0649
ATGAGCGGGCGAAGCCGATTGCCCGGCTCCTCCTCACGCCGCGACGCGGCGCGCATCGTC
GCCGAGCGGGTGGTCGCGACCGTCGCCGGTGTCGCGGTAGCGGTCGACGAGGTCGACGCG
GCCGAAGCGCGGCTGCGCGACGGACCGCGCGCGGCCGCGCTGCCGGCGAGCGGCACCAGC
GAGGGACGCCAACTGCGGCGCTGGCTCACCCAACTGATCGTGACCGAGCGGGTGGTAGCC
GCCGAGGCCGCCGCACGTGGTCTGACCGCGGCGGGCGCCCCCGCCGAGGCGGACCTGCTG
CCCGACGCGACGGCTCGGCTGGAGATCGGCAGCGTCGCCGCCGCGGTGCTGGCGGATCCT
TTGGCGCGGGCGTTGTTCGCCGCCGTCACCGCGCGGGTCGCGGTCACCGACGACGCCGTG
GCCGACTACCATGCCCGCAACCCGCTGCGGTTCGCCGCGCCATGTCCCGGCCAGCACGGC
TGGCGTGCCCCGGCGGCGGCCGCCCCACCGCTGGATCAGGTGCGCCGCGCGATCACCGAG
CATCTGTTGGGGGCCGCGCGCCGCCGCGCCTTCCGGGTGTGGCTGGACGCGCGCCGGAAC
GCCCTGGTGGTGCTGGCCCCCGGCTATGAGCACCCCGGCGACCCGCGCCAACCCGACAAC
ACCCGCCGGCACTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv1221	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. R. Manganelli, MI. Voskuil et al. The Mycobacterium tuberculosis ECF sigma factor sigmaE: role in global gene expression and survival in macrophages. Mol. Microbiol. 2001
Name	MALONYL CoA-ACYL CARRIER PROTEIN TRANSACYLASE	active	mjackson	2012-10-05
	FAS-I->FAS-II
Name	MALONYL CoA-ACYL CARRIER PROTEIN TRANSACYLASE	active	mjackson	2012-10-05
	FAS-I->FAS-II
Term	EC:2.3.1.38 [Acyl-carrier-protein] S-acetyltransferase. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay K. Takayama, C. Wang et al. Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis. Clin. Microbiol. Rev. 2005
Term	EC:2.3.1.39 [Acyl-carrier-protein] S-malonyltransferase. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay K. Takayama, C. Wang et al. Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis. Clin. Microbiol. Rev. 2005
Term	EC:6.4.1.2 Acetyl-CoA carboxylase. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay K. Takayama, C. Wang et al. Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis. Clin. Microbiol. Rev. 2005