Rv0777 - adenylosuccinate lyase purB

Expression: Most Significant Conditions for Rv0777

Protein Domains

Gene Information
Locus	Rv0777
Symbol	purB
Gene Name	adenylosuccinate lyase purB
Location	870008 - 871426 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1419 bp Protein:473 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	33267
Related Genes	Acel_2128 CE2488 cg2876 DIP1928 jk0349 MAP0611 MAV_0722 Mkms_4654 ML2230 Mmcs_4566 MSMEG_5847 MT0801 MUL_0490 Mvan_5145 nfa5590 PPA1992 SAV7077
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0777
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0777 Transcript 1
MSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD
DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF
AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR
YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV
SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR
GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE
LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR
LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL*

Genomic Sequence

>Rv0777
GTGAGCATTCCCAACGTGCTGGCCACCCGATACGCCAGCGCCGAGATGGTCGCGATCTGG
TCGCCGGAGGCCAAGGTGGTCTCGGAGCGGCGGTTATGGCTGGCCGTATTGCGGGCACAG
GCAGAGCTGGGGGTAGCGGTTGCCGATTCGGTGCTCGCCGACTACGAACGTGTGGTCGAC
GATGTGGACTTGGCCTCGATCTCAGCCCGGGAGCGGGTGCTGCGCCACGATGTCAAGGCC
CGCATCGAGGAATTCAACGCATTGGCCGGTCATGAGCACGTGCACAAGGGGATGACCAGC
CGCGACCTGACCGAGAACGTGGAGCAACTGCAGATTCGGCGGTCGCTGGAAGTGATTTTC
GCCCATGGGGTGGCGGCGGTGGCGCGGCTGGCCGAGCGGGCGGTGAGCTACCGTGACCTG
ATCATGGCCGGGCGCAGCCACAACGTGGCCGCTCAGGCCACCACCTTGGGCAAGCGGTTC
GCCTCGGCGGCCCAAGAGATGATGATCGCGTTGAGGCGGTTGAGGGAGTTGATCGACCGC
TACCCCCTGCGTGGCATCAAGGGCCCGATGGGCACCGGTCAGGACATGCTCGATCTGCTG
GGCGGTGACCGTGCGGCGCTGGCCGATCTCGAGCGGCGCGTCGCCGACTTCTTGGGCTTT
GCAACTGTTTTCAACAGCGTGGGGCAGGTGTATCCGCGTTCATTGGACCACGACGTGGTT
TCGGCTCTGGTGCAGCTCGGCGCGGGGCCGTCATCACTGGCACACACGATTCGATTGATG
GCCGGCCACGAGCTCGCCACCGAGGGTTTCGCGCCGGGTCAGGTCGGTTCGTCGGCGATG
CCGCACAAGATGAACACCCGCAGCTGCGAACGGGTCAACGGGCTGCAGGTTGTGCTACGC
GGCTATGCATCCATGGTGGCCGAGTTAGCCGGTGCACAGTGGAACGAGGGTGATGTGTTT
TGCTCCGTGGTGCGCCGGGTTGCGTTGCCGGACAGCTTCTTTGCCGTCGACGGGCAGATC
GAGACGTTTTTGACGGTGCTGGACGAGTTCGGCGCCTACCCGGCGGTGATCGGCCGCGAG
TTGGATCGTTATCTGCCGTTCCTGGCCACCACTAAGGTGCTAATGGCGGCCGTGCGCGCG
GGGATGGGTCGCGAGTCCGCGCACCGGTTGATCTCCGAGCACGCGGTGGCGACGGCGCTG
GCCATGCGAGAACACGGCGCGGAGCCCGACCTGCTGGACCGGTTGGCCGCCGATCCGCGG
CTGACGCTGGGACGAGACGCTTTGGAGGCCGCGCTGGCCGACAAGAAGGCATTTGCCGGT
GCCGCGGGTGACCAGGTCGATGATGTGGTCGCGATGGTGGACGCGCTGGTGAGCCGTTAC
CCGGACGCGGCTAAATACACGCCGGGTGCAATTCTTTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv3575c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv3575c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006