Rv0780 - phosphoribosylaminoimidazole-succinocarboxamide synthase purC

Expression: Most Significant Conditions for Rv0780

Protein Domains

Gene Information
Locus	Rv0780
Symbol	hemH
Gene Name	phosphoribosylaminoimidazole-succinocarboxamide synthase purC
Location	873343 - 874236 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:894 bp Protein:298 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	32532
Related Genes	Acel_2129 BL1107 CE2487 cg2874 DIP1927 jk0350 MAP0614 MAV_0725 Mkms_4648 ML2227 Mmcs_4560 MSMEG_5841 MT0804 MUL_0497 Mvan_5138 nfa13190 PPA1988 SAV4146
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0780
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0780 Transcript 1
MRPALSDYQHVASGKVREIYRVDDEHLLLVASDRISAYDYVLDSTIPDKGRVLTAMSAFF
FGLVDAPNHLAGPPDDPRIPDEVLGRALVVRRLEMLPVECVARGYLTGSGLLDYQATGKV
CGIALPPGLVEASRFATPLFTPATKAALGDHDENISFDRVVEMVGALRANQLRDRTLQTY
VQAADHALTRGIIIADTKFEFGIDRHGNLLLADEIFTPDSSRYWPADDYRAGVVQTSFDK
QFVRSWLTGSESGWDRGSDRPPPPLPEHIVEATRARYINAYERISELKFDDWIGPGA*

Genomic Sequence

>Rv0780
ATGCGCCCCGCATTGTCCGACTACCAGCATGTGGCCAGCGGTAAGGTCCGCGAGATCTAC
CGTGTCGATGACGAGCACCTGCTGCTGGTTGCCAGCGACCGGATCTCGGCGTACGACTAC
GTCCTGGACAGCACCATCCCGGACAAGGGCCGCGTCCTGACCGCCATGAGCGCATTCTTC
TTCGGGCTCGTCGATGCCCCTAACCATCTGGCCGGGCCGCCGGACGACCCGCGTATCCCC
GACGAGGTGCTGGGCCGCGCGCTGGTGGTGCGTCGGCTGGAGATGCTGCCGGTGGAATGT
GTGGCCCGTGGCTACCTGACCGGTTCGGGGTTACTGGATTACCAGGCAACCGGGAAGGTA
TGCGGTATCGCGCTGCCGCCGGGCCTGGTCGAGGCCAGTCGGTTCGCCACACCGCTGTTC
ACCCCGGCGACTAAAGCCGCGTTGGGGGACCACGACGAGAACATCTCGTTTGACCGGGTG
GTGGAGATGGTAGGCGCGTTGCGTGCCAACCAGCTGCGTGATCGTACTCTGCAGACGTAT
GTGCAGGCCGCCGATCACGCTCTCACCCGCGGAATCATTATCGCCGACACCAAGTTTGAA
TTTGGCATCGACCGCCACGGCAACCTGCTGCTGGCCGACGAAATCTTCACACCGGACTCG
TCGCGGTACTGGCCTGCCGACGACTACCGGGCCGGCGTGGTCCAGACCAGCTTCGACAAA
CAGTTTGTCCGCAGCTGGCTCACCGGCTCCGAGTCCGGCTGGGATAGAGGCAGCGATCGG
CCGCCGCCTCCGCTCCCCGAGCATATCGTCGAGGCCACGCGTGCCCGTTATATTAATGCA
TACGAACGGATTTCCGAACTAAAATTCGACGACTGGATCGGCCCTGGCGCATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv3575c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv3575c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006
Term	EC:6.3.2.6 Phosphoribosylaminoimidazolesuccinocarboxamide synthase. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay authors,M. Jackson,SW. Phalen,M. Lagranderie,D. Ensergueix,P. Chavarot,G. Marchal,DN. McMurray,B. Gicquel,C. Guilhot Persistence and protective efficacy of a Mycobacterium tuberculosis auxotroph vaccine. Infect. Immun. 1999