Rv0969 - metal cation transporting P-type ATPase ctpV

Expression: Most Significant Conditions for Rv0969

Protein Domains

Gene Information
Locus	Rv0969
Symbol	ctpV
Gene Name	metal cation transporting P-type ATPase ctpV
Location	1078743 - 1081055 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:2313 bp Protein:771 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	35632
Related Genes	MT0997 MUL_0423
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv0969
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv0969 Transcript 1
MRVCVTGFNVDAVRAVAIEETVSQVTGVHAVHAYPRTASVVIWYSPELGDTAAVLSAITK
AQHVPAELVPARAPHSAGVRGVGVVRKITGGIRRMLSRPPGVDKPLKASRCGGRPRGPVR
GSASWPGEQNRRERRTWLPRVWLALPLGLLALGSSMFFGAYPWAGWLAFAATLPVQFVAG
WPILRGAVQQARALTSNMDTLIALGTLTAFVYSTYQLFAGGPLFFDTSALIIAFVVLGRH
LEARATGKASEAISKLLELGAKEATLLVDGQELLVPVDQVQVGDLVRVRPGEKIPVDGEV
TDGRAAVDESMLTGESVPVEKTAGDRVAGATVNLDGLLTVRATAVGADTALAQIVRLVEQ
AQGDKAPVQRLADRVSAVFVPAVIGVAVATFAGWTLIAANPVAGMTAAVAVLIIACPCAL
GLATPTAIMVGTGRGAELGILVKGGEVLEASKKIDTVVFDKTGTLTRARMRVTDVIAGQR
RQPDQVLRLAAAVESGSEHPIGAAIVAAAHERGLAIPAANAFTAVAGHGVRAQVNGGPVV
VGRRKLVDEQHLVLPDHLAAAAVEQEERGRTAVFVGQDGQVVGVLAVADTVKDDAADVVG
RLHAMGLQVAMITGDNARTAAAIAKQVGIEKVLAEVLPQDKVAEVRRLQDQGRVVAMVGD
GVNDAPALVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVRAIELSRQTLRTIYQNLGW
AFGYNTAAIPLAALGALNPVVAGAAMGFSSVSVVTNSLRLRRFGRDGRTA*

Genomic Sequence

>Rv0969
ATGCGCGTGTGCGTCACCGGGTTCAATGTCGATGCGGTTCGGGCCGTCGCGATTGAGGAG
ACGGTCTCCCAAGTGACCGGGGTGCACGCCGTGCACGCCTATCCGCGAACAGCGTCGGTG
GTGATCTGGTACTCGCCAGAGCTCGGTGACACCGCCGCCGTGCTGTCGGCGATCACCAAA
GCGCAGCACGTCCCGGCAGAATTGGTGCCCGCCCGTGCCCCGCACTCAGCGGGTGTGCGC
GGCGTGGGCGTGGTGCGGAAAATCACCGGCGGGATCCGCCGCATGCTAAGTCGCCCGCCG
GGCGTCGACAAGCCCCTGAAGGCGTCGCGTTGCGGCGGCCGCCCGCGCGGGCCGGTCCGC
GGGAGCGCCTCGTGGCCGGGCGAGCAGAACCGGCGCGAGCGGCGGACGTGGTTGCCGCGG
GTGTGGTTGGCCTTGCCGTTGGGGCTACTGGCGCTGGGTTCGTCAATGTTCTTCGGTGCT
TACCCGTGGGCGGGGTGGCTGGCCTTCGCCGCGACGCTGCCGGTGCAATTCGTGGCCGGG
TGGCCGATTCTGCGGGGGGCGGTGCAACAGGCGCGGGCGTTGACCTCGAACATGGACACG
CTGATCGCGCTGGGTACGCTGACCGCGTTTGTCTACTCCACGTATCAGTTGTTTGCCGGT
GGACCTCTGTTCTTCGACACCTCGGCGCTGATCATCGCGTTCGTGGTGTTGGGCCGCCAT
CTCGAGGCCAGAGCAACCGGAAAAGCGTCCGAGGCGATCAGCAAGCTGCTGGAGCTGGGC
GCCAAGGAAGCCACGCTGCTTGTCGACGGCCAAGAGCTCCTGGTGCCGGTCGATCAGGTC
CAAGTCGGAGACCTGGTGCGGGTGCGGCCCGGAGAGAAGATCCCGGTCGACGGTGAGGTC
ACCGATGGGCGCGCCGCCGTCGACGAGTCGATGCTCACCGGCGAATCCGTCCCGGTCGAG
AAGACGGCGGGTGACCGCGTTGCCGGCGCAACGGTCAACCTCGACGGGCTGTTGACCGTG
CGCGCCACCGCCGTCGGGGCAGACACCGCGCTGGCGCAGATTGTGCGACTGGTCGAGCAG
GCACAGGGCGACAAGGCGCCGGTGCAGCGGCTGGCCGACCGGGTTTCGGCGGTGTTTGTC
CCGGCCGTCATCGGCGTTGCCGTCGCGACCTTTGCGGGATGGACCCTGATCGCCGCCAAC
CCGGTGGCTGGTATGACCGCCGCGGTCGCGGTGCTGATCATCGCGTGCCCGTGTGCGTTG
GGCCTGGCTACCCCCACGGCCATCATGGTCGGCACCGGCCGGGGCGCCGAACTGGGGATC
CTGGTCAAGGGAGGCGAGGTGCTGGAAGCGTCGAAGAAGATCGACACCGTGGTGTTCGAC
AAGACCGGCACCCTCACCCGCGCCCGGATGCGGGTGACCGATGTGATTGCCGGCCAGCGG
CGCCAGCCTGATCAGGTGCTGCGGCTCGCCGCCGCGGTCGAATCGGGCTCCGAACACCCC
ATCGGTGCGGCGATCGTTGCCGCTGCACACGAGCGCGGGTTGGCGATACCGGCCGCCAAT
GCGTTCACCGCCGTCGCCGGGCACGGGGTGCGGGCGCAGGTCAACGGCGGGCCGGTGGTG
GTCGGACGGCGCAAGCTCGTCGACGAACAACATTTGGTTCTGCCCGACCACCTCGCTGCG
GCGGCCGTGGAGCAGGAAGAGCGCGGCCGCACCGCGGTGTTCGTCGGCCAAGACGGCCAG
GTTGTGGGTGTGCTCGCGGTAGCGGACACGGTCAAAGACGACGCCGCGGACGTGGTCGGT
CGGCTGCACGCCATGGGGCTACAGGTAGCCATGATCACCGGCGACAACGCCCGCACGGCT
GCCGCGATCGCCAAGCAGGTCGGCATCGAGAAGGTGCTGGCCGAGGTGTTGCCGCAGGAC
AAGGTAGCTGAGGTTCGGCGGCTGCAGGACCAGGGCCGGGTGGTCGCGATGGTGGGTGAC
GGCGTCAACGACGCGCCCGCCTTGGTACAAGCCGATCTGGGCATTGCGATCGGCACCGGT
ACCGACGTGGCCATCGAGGCCTCCGACATCACGCTAATGTCCGGCCGGCTCGATGGTGTC
GTGCGCGCGATCGAACTCTCCAGGCAGACCCTGCGCACCATCTACCAGAATCTCGGCTGG
GCCTTCGGCTACAACACCGCCGCGATCCCACTGGCCGCGCTGGGCGCGCTGAACCCGGTC
GTGGCGGGCGCGGCGATGGGGTTCTCCTCGGTCAGCGTGGTGACCAACTCACTGCGGTTA
CGCCGCTTCGGCCGCGACGGCCGAACCGCATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv0182c	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. JH. Lee, DE. Geiman et al. Role of stress response sigma factor SigG in Mycobacterium tuberculosis. J. Bacteriol. 2008
Interaction	RegulatedBy Rv0967	active	yamir.moreno	2012-10-05
	qRT-PCR. mRNA expression levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using qRT-PCR technique. authors,T. Liu,A. Ramesh,Z. Ma,SK. Ward,L. Zhang,GN. George,AM. Talaat,JC. Sacchettini,DP. Giedroc CsoR is a novel Mycobacterium tuberculosis copper-sensing transcriptional regulator. Nat. Chem. Biol. 2007
Interaction	RegulatedBy Rv3334	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv0967	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv3334	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006