Rv1005c - para-aminobenzoate synthase component I pabD

Expression: Most Significant Conditions for Rv1005c

Protein Domains

Gene Information
Locus	Rv1005c
Symbol	pabB
Gene Name	para-aminobenzoate synthase component I pabD
Location	1122222 - 1123598 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1377 bp Protein:459 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	36806
Related Genes	MAP0945c MAV_1127 Mkms_4358 ML0236 Mmcs_4272 MSMEG_5446 MT1034 MUL_4660 Mvan_4807 nfa16010
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1005c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1005c Transcript 1
MNLAWELSTRTKSPRSHLRCENPQFCQARTVRIDRLGDLGGAPAVLRAVGRATSRLDLPP
PAALTGEWFGALAVIAPSVSIQPVSGDDVFSGPPGTGGPDATGAVGGGWVGYLSYPDAGA
DGRPHRIPEAAGGWTDCVLRRDRDGQWWYESLSGAPIADWLASALATTRASVARPAPACR
IDWEPADRAAHRDGVLACLEAIGAGEVYQACVCTQFAGTVTGSPLDFFIDGFGRTAPSRS
AFVAGPWGAVASLSPELFLRRRGSVVTSSPIKGTLPLDAPPSALRASAKEVAENIMIVDL
VRNDLGRVAVTGTVTVPELLVVRPAPGVWHLVSTVSARVPLEEPMSALLDAAFPPASVTG
TPKLRARQLISQWERYRRGIYCGTVGLASPVAGCELNVAIRTVEFDTAGNAVLGVGGGIT
ADSDPDAEWAECLHKAAPIVGLPAATRTTPARLASKVR*

Genomic Sequence

>Rv1005c
TTGAACTTAGCGTGGGAGCTTAGCACGCGGACGAAATCCCCACGCAGCCACTTGCGCTGC
GAAAATCCACAGTTCTGTCAAGCTAGAACGGTGCGAATCGACCGACTCGGCGATCTTGGC
GGAGCGCCTGCGGTGCTGCGGGCGGTCGGCCGCGCCACCAGTCGACTCGACTTGCCACCA
CCGGCGGCGCTGACCGGCGAATGGTTCGGTGCGCTGGCGGTGATCGCACCGAGTGTGTCT
ATACAACCGGTCAGCGGCGACGACGTGTTCTCGGGCCCGCCGGGCACCGGCGGGCCCGAT
GCCACCGGGGCGGTGGGCGGCGGCTGGGTCGGCTACCTGTCCTACCCGGACGCCGGCGCC
GACGGGCGACCCCACCGGATCCCCGAGGCCGCCGGCGGCTGGACCGATTGCGTGCTGCGC
CGCGACCGCGACGGCCAGTGGTGGTATGAGAGCCTGTCCGGTGCGCCGATAGCGGACTGG
CTGGCCAGCGCGTTGGCGACCACTCGGGCATCGGTCGCCAGACCGGCACCGGCATGCCGG
ATCGACTGGGAACCGGCCGACCGGGCAGCGCACCGCGACGGGGTACTGGCGTGTCTGGAA
GCTATCGGCGCGGGCGAGGTCTATCAAGCGTGCGTGTGCACCCAATTCGCCGGGACGGTC
ACCGGATCCCCGCTGGACTTCTTCATCGACGGGTTCGGTCGTACCGCTCCGTCCCGGTCC
GCCTTTGTCGCCGGACCGTGGGGAGCCGTCGCATCGCTATCCCCGGAGCTATTCCTGCGC
CGCCGCGGGTCCGTGGTGACATCGAGCCCGATCAAGGGCACGCTGCCGCTGGACGCCCCG
CCGTCGGCGCTGCGGGCATCGGCCAAAGAGGTGGCCGAGAACATCATGATCGTGGATCTG
GTCCGCAACGACCTCGGCCGGGTAGCGGTTACCGGTACCGTGACGGTGCCCGAGCTGTTG
GTGGTGCGACCAGCGCCGGGAGTGTGGCACCTGGTGTCCACGGTGTCGGCGCGGGTTCCG
CTCGAGGAACCGATGTCAGCGCTGCTCGACGCCGCCTTCCCGCCGGCCTCGGTCACCGGC
ACACCTAAACTGCGGGCTCGCCAATTGATTTCACAATGGGAGCGATATCGCCGCGGGATA
TATTGCGGCACAGTCGGTTTGGCGTCACCGGTCGCCGGATGCGAGCTCAACGTCGCAATC
CGCACCGTCGAATTCGATACCGCAGGCAACGCCGTGCTGGGCGTTGGCGGCGGGATCACC
GCCGACTCCGATCCGGACGCCGAATGGGCGGAGTGCCTGCACAAAGCCGCTCCCATCGTC
GGGCTGCCGGCCGCCACGCGCACCACCCCGGCTCGGTTAGCCAGCAAAGTGCGGTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	PhysicalInteraction Rv0013	active	shahanup86	2012-10-05
	Co-occurrence (Functional linkage) authors,J. Slock,DP. Stahly,CY. Han,EW. Six,IP. Crawford An apparent Bacillus subtilis folic acid biosynthetic operon containing pab, an amphibolic trpG gene, a third gene required for synthesis of para-aminobenzoic acid, and the dihydropteroate synthase gene. J. Bacteriol. 1990
Interaction	PhysicalInteraction Rv0013	active	shahanup86	2012-10-05
	Co-occurrence (Functional linkage) authors,BP. Nichols,AM. Seibold,SZ. Doktor para-aminobenzoate synthesis from chorismate occurs in two steps. J. Biol. Chem. 1989
Interaction	PhysicalInteraction Rv0013	active	shahanup86	2012-10-05
	Co-occurrence (Functional linkage) AJ. Harrison, M. Yu et al. The structure of MbtI from Mycobacterium tuberculosis, the first enzyme in the biosynthesis of the siderophore mycobactin, reveals it to be a salicylate synthase. J. Bacteriol. 2006