Rv1011 - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE

Expression: Most Significant Conditions for Rv1011

Protein Domains

Gene Information
Locus	Rv1011
Symbol	ispE
Gene Name	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE
Location	1130191 - 1131111 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:921 bp Protein:307 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	393
Related Genes	Acel_0181 BL0656 CE0973 cg1039 DIP0876 jk1510 MAP0976 MAV_1149 Mkms_4348 ML0242 Mmcs_4262 MSMEG_5436 MT1040 MUL_4649 Mvan_4799 nfa49010 PPA0527 SAV3586
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1011
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1011 Transcript 1
MPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEG
ADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSL
WELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLL
TSAVYNELDRLREVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA
LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV
SAPTEV*

Genomic Sequence

>Rv1011
GTGCCCACCGGGTCGGTCACCGTTCGGGTGCCCGGAAAGGTCAACCTCTATCTGGCGGTC
GGCGATCGCCGCGAGGACGGCTATCACGAGCTGACCACGGTATTTCATGCCGTCTCGCTG
GTCGACGAGGTAACCGTTCGTAACGCTGATGTGCTCTCGCTCGAGTTGGTCGGCGAGGGG
GCCGACCAGCTGCCGACCGACGAACGCAATCTCGCCTGGCAGGCGGCCGAGCTGATGGCC
GAACACGTGGGCCGGGCGCCGGACGTCTCGATCATGATCGACAAATCCATTCCGGTCGCC
GGCGGCATGGCCGGTGGCAGCGCGGACGCTGCGGCGGTCCTGGTTGCGATGAACTCGTTG
TGGGAACTCAATGTGCCCCGCCGCGACCTGCGCATGCTCGCCGCGCGGCTAGGCAGCGAT
GTGCCGTTTGCCCTGCATGGTGGTACCGCGCTGGGGACGGGTCGCGGCGAGGAGTTGGCC
ACCGTGTTATCCCGCAACACCTTCCACTGGGTCCTGGCGTTCGCCGACAGCGGGTTGCTC
ACCTCCGCGGTGTACAACGAGCTCGACCGGCTCAGGGAGGTGGGGGATCCGCCCCGGCTT
GGTGAGCCCGGGCCGGTTCTGGCTGCCTTAGCTGCGGGTGATCCGGATCAGCTGGCGCCG
TTGCTGGGTAATGAAATGCAAGCGGCCGCGGTGAGCCTGGACCCGGCGCTGGCTCGTGCG
TTACGCGCCGGTGTGGAGGCCGGCGCGCTCGCAGGCATCGTGTCCGGTTCGGGTCCCACG
TGTGCCTTCCTGTGCACCTCGGCGAGCTCGGCGATCGATGTCGGCGCGCAGCTGTCGGGG
GCGGGAGTTTGTCGCACCGTTCGAGTCGCCACCGGGCCGGTACCCGGCGCCCGCGTGGTG
TCTGCGCCGACCGAAGTGTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Term	TBRXN:CDPMEK 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - ISS	active	njamshidi	2012-10-05
	PMID: 16321944 RK. Dhiman, ML. Schaeffer et al. 1-Deoxy-D-xylulose 5-phosphate reductoisomerase (IspC) from Mycobacterium tuberculosis: towards understanding mycobacterial resistance to fosmidomycin. J. Bacteriol. 2005
Term	TBRXN:CDPMEK 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase - IDA	active	njamshidi	2012-10-05
	PMID: 16321944 RK. Dhiman, ML. Schaeffer et al. 1-Deoxy-D-xylulose 5-phosphate reductoisomerase (IspC) from Mycobacterium tuberculosis: towards understanding mycobacterial resistance to fosmidomycin. J. Bacteriol. 2005
Name	CDP-2-C-methyl-D-erythritol 4-phosphate kinase	active	mjackson	2012-10-05
	Non-mevalonate isopentenyl diphosphate synthesis