Rv1021 - conserved hypothetical protein

Expression: Most Significant Conditions for Rv1021

Protein Domains

Gene Information
Locus	Rv1021
Symbol
Gene Name	conserved hypothetical protein
Location	1142671 - 1143648 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:978 bp Protein:326 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	32753
Related Genes	Acel_1910 BL0851 CE1037 cg1107 DIP0915 jk1489 MAP0988 MAV_1162 Mkms_4330 Mmcs_4244 MSMEG_5422 MT1049 MUL_4633 Mvan_4776 nfa48740 PPA0543 SAV3537
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1021
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1021 Transcript 1
MIVVLVDPRRPTLVPVEAIEFLRGEVQYTEEMPVAVPWSLPAARSAHAGNDAPVLLSSDP
NHPAVITRLAAGARLISAPDSQRGERLVDAVAMMDKLRTAGPWESEQTHDSLRRYLLEET
YELLDAVRSGSVDQLREELGDLLLQVLFHARIAEDASQSPFTIDDVADTLMRKLGNRAPG
VLAGESISLEDQLAQWEAAKASEKARKSVADDVHTGQPALALAQKVIQRAQKAGLPAHLI
PDEITSVSVSADVDAENTLRTAVLDFIDRLRCAERAIAVARRGSNVAEQLDVTPLGVITE
QEWLAHWPTAVNDSRGGSKKRKGMR*

Genomic Sequence

>Rv1021
ATGATTGTCGTCCTGGTCGACCCCCGGCGTCCGACACTGGTGCCTGTTGAAGCGATCGAG
TTCCTGCGCGGCGAGGTGCAATACACCGAGGAAATGCCGGTCGCGGTGCCCTGGTCGCTA
CCAGCGGCTCGTTCGGCGCACGCCGGAAACGACGCGCCGGTGTTGCTGTCGTCTGACCCC
AACCATCCTGCTGTCATTACTCGACTGGCCGCCGGTGCCCGGCTGATCTCGGCACCGGAT
TCTCAGCGTGGCGAACGACTCGTCGACGCCGTCGCGATGATGGACAAGCTGCGCACCGCC
GGACCGTGGGAAAGTGAGCAGACTCACGACTCGCTGCGCAGATACCTGCTGGAGGAGACC
TACGAGCTGTTGGACGCGGTCCGCAGCGGCAGTGTTGACCAGCTGCGCGAAGAGCTTGGT
GATCTCTTGCTGCAGGTCCTCTTTCACGCCCGGATCGCTGAGGATGCGTCGCAATCGCCG
TTCACCATCGACGACGTCGCCGACACACTGATGCGAAAGCTCGGCAATCGGGCGCCAGGA
GTACTTGCGGGCGAATCGATTTCGCTCGAAGATCAACTGGCGCAATGGGAGGCAGCCAAG
GCCTCGGAAAAGGCGCGAAAGTCGGTAGCCGACGATGTCCATACGGGCCAGCCGGCATTA
GCGCTGGCGCAGAAGGTTATTCAGCGTGCCCAAAAGGCTGGGCTGCCCGCTCACCTGATC
CCCGATGAGATCACTTCTGTTTCGGTTTCAGCTGACGTAGATGCGGAAAACACGCTGCGC
ACTGCCGTTTTGGACTTTATTGACAGGCTGCGCTGTGCCGAGCGGGCAATTGCCGTCGCA
CGCCGGGGCAGCAACGTTGCCGAGCAGCTCGATGTGACGCCGCTGGGTGTGATCACCGAG
CAGGAGTGGCTCGCGCATTGGCCAACTGCTGTCAACGATTCCCGCGGCGGGTCCAAGAAA
CGTAAAGGCATGCGATAA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Other	TBPWY:Nucleotide pool	active	vmizrahi	2012-03-05
	Potent nucleoside triphosphate pyrophosphohydrolase capable of hydrolyzing all canonical (d)NTPs, as well as the mutagenic dUTP and 8-oxo-7,8-dihydro-2'-dGTP. However, this hydrolysis activity is diminished by the A219E mutation. Over-expression Importantly, expression of the wild-type MtMazG, but not the A219E mutant, complemented the oxidatove stress hypersensitivity phenotype of a mazG mutant of M. smegmatis
Symbol	mazG	active	vmizrahi	2012-03-05
	Potent nucleoside triphosphate pyrophosphohydrolase capable of hydrolyzing all canonical (d)NTPs, as well as the mutagenic dUTP and 8-oxo-7,8-dihydro-2'-dGTP. However, this hydrolysis activity is diminished by the A219E mutation. Over-expression Importantly, expression of the wild-type MtMazG, but not the A219E mutant, complemented the oxidatove stress hypersensitivity phenotype of a mazG mutant of M. smegmatis