Rv1098c - fumarase fum

Expression: Most Significant Conditions for Rv1098c

Protein Domains

Gene Information
Locus	Rv1098c
Symbol	fumC
Gene Name	fumarase fum
Location	1226141 - 1227565 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1425 bp Protein:475 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	33603
Related Genes	Acel_1879 BL0338 CE1071 cg1145 DIP0938 jk1454 MAP2693 MAV_1221 Mkms_4197 ML1947 Mmcs_4122 MSMEG_5240 MT1130 MUL_0181 Mvan_4649 nfa48010 PPA2292 SAV3221
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1098c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1098c Transcript 1
MAVDADSANYRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERTQIRALGLLKGA
CAQVNSDLGLLAPEKADAIIAAAAEIADGQHDDQFPIDVFQTGSGTSSNMNTNEVIASIA
AKGGVTLHPNDDVNMSQSSNDTFPTATHIAATEAAVAHLIPALQQLHDALAAKALDWHTV
VKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRACLPRLGELAIGGTAVGTGLNAPDD
FGVRVVAVLVAQTGLSELRTAANSFEAQAARDGLVEASGALRTIAVSLTKIANDIRWMGS
GPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGNDAAIAWGGANGAFELNV
YIPMMARNILESFKLLTNVSRLFAQRCIAGLTANVEHLRRLAESSPSIVTPLNSAIGYEE
AAAVAKQALKERKTIRQTVIDRGLIGDRLSIEDLDRRLDVLAMAKAEQLDSDRL*

Genomic Sequence

>Rv1098c
ATGGCCGTTGACGCCGACAGCGCCAATTACCGCATCGAGCACGACACCATGGGCGAAGTC
CGGGTGCCGGCAAAAGCGTTGTGGCGCGCGCAAACCCAGCGCGCGGTGGAGAACTTCCCG
ATATCCGGCCGCGGGTTGGAGCGCACCCAGATCCGCGCGCTAGGCCTGCTGAAAGGCGCC
TGCGCGCAGGTGAACTCCGACCTCGGGTTGCTGGCGCCGGAGAAAGCCGACGCCATCATC
GCCGCGGCCGCCGAGATCGCCGACGGTCAACACGACGACCAGTTTCCCATCGACGTCTTC
CAGACCGGCTCGGGCACCAGCTCCAACATGAACACCAACGAGGTGATTGCGTCCATCGCG
GCCAAGGGCGGGGTCACGTTGCATCCCAACGACGACGTGAACATGTCGCAGTCGTCCAAC
GACACCTTCCCGACGGCCACCCACATCGCGGCCACCGAGGCCGCGGTCGCTCATCTCATC
CCAGCGCTGCAGCAGCTGCACGACGCATTGGCCGCCAAGGCTCTTGATTGGCACACGGTG
GTGAAGTCGGGCCGAACGCATCTGATGGACGCCGTTCCGGTGACACTCGGCCAGGAGTTC
AGCGGATATGCCCGCCAGATCGAGGCCGGCATCGAGCGGGTGCGCGCGTGTCTGCCCAGG
CTGGGCGAGCTGGCGATCGGCGGCACCGCGGTGGGTACCGGCCTCAACGCTCCCGACGAC
TTCGGCGTCAGAGTGGTCGCGGTGCTGGTCGCGCAGACCGGTCTGTCGGAATTGCGTACG
GCGGCTAATTCTTTCGAAGCTCAGGCTGCCCGCGACGGGCTGGTGGAGGCGTCCGGGGCG
CTGCGCACGATCGCGGTATCGCTGACCAAGATCGCCAACGACATCCGCTGGATGGGATCG
GGCCCATTGACCGGCCTGGCCGAGATCCAACTGCCAGATCTGCAGCCGGGCAGCTCGATC
ATGCCGGGAAAGGTGAATCCGGTTCTGCCGGAGGCGGTTACGCAGGTCGCCGCGCAGGTG
ATCGGAAACGACGCCGCCATCGCCTGGGGTGGGGCCAACGGCGCATTCGAACTCAACGTC
TACATCCCGATGATGGCCCGCAACATCCTCGAGTCCTTCAAGCTGCTGACCAATGTGTCA
CGGCTGTTCGCCCAGCGCTGCATAGCAGGGCTGACCGCCAACGTCGAGCACCTGCGGCGG
CTGGCCGAGTCCTCACCGTCGATCGTGACACCGTTGAATTCGGCCATCGGCTACGAGGAG
GCGGCCGCCGTCGCCAAGCAAGCACTCAAGGAACGCAAAACGATTCGCCAAACCGTGATC
GACCGTGGCCTGATCGGCGACAGGCTGTCGATCGAGGATCTGGACCGCCGTCTGGACGTG
CTGGCAATGGCCAAGGCCGAGCAGCTCGACAGCGATCGGCTATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv1931c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv1931c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006
Term	EC:4.2.1.2 Fumarate hydratase. - NR	active	extern:JZUCKER	2012-03-06
	Traceable author statement to experimental support authors,KY. Rhee,LP. de Carvalho,R. Bryk,S. Ehrt,J. Marrero,SW. Park,D. Schnappinger,A. Venugopal,C. Nathan Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. Trends Microbiol. 2011