Rv1159 - conserved membrane protein

Expression: Most Significant Conditions for Rv1159

Protein Domains

Gene Information
Locus	Rv1159
Symbol
Gene Name	conserved membrane protein
Location	1284992 - 1286287 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1296 bp Protein:432 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	28774
Related Genes	MAP2624c MAV_1298 Mkms_4120 ML1504 Mmcs_4045 MSMEG_5149 MT1195 MUL_1006 Mvan_4550 nfa47620
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1159
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1159 Transcript 1
MCRTLIDGPVRSAIAKVRQIDTTSSTPAAARRVTSPPARETRAAVLLLVLSVGARLAWTY
LAPNGANFVDLHVYVSGAASLDHPGTLYGYVYADQTPDFPLPFTYPPFAAVVFYPLHLVP
FGLIALLWQVVTMAALYGAVRISQRLMGGTAETGHFAAMLWTAIAIWIEPLRSTFDYGQI
NVLLMLAALWAVYTPRWWLSGLLVGVASGVKLTPAITAVYLVGVRRLHAAAFSVVVFLAT
VGVSLLVVGDEARYYFTDLLGDAGRVGPIATSFNQSWRGAISRILGHDAGFGPLVLAAIA
STAVLAILAWRALDRSDRLGKLLVVELFGLLLSPISWTHHWVWLVPLMIWLIDGPARERP
GARILGWGWLVLTIVGVPWLLSFAQPSIWQIGRPWYLAWAGLVYVVATLATLGWIAASER
YVRIRPRRMAN*

Genomic Sequence

>Rv1159
ATGTGCCGCACCCTGATCGACGGCCCGGTGCGCTCGGCGATCGCTAAAGTCAGGCAGATA
GACACCACCTCATCCACCCCGGCGGCCGCCAGGCGCGTGACCTCACCACCGGCCCGGGAG
ACACGCGCCGCCGTGCTGCTACTGGTCCTCAGCGTCGGTGCGCGACTCGCCTGGACCTAT
CTGGCGCCCAACGGCGCAAACTTCGTCGACCTGCACGTTTACGTGAGCGGTGCAGCGTCC
CTCGACCATCCCGGCACCCTGTATGGCTACGTCTACGCTGATCAGACCCCGGACTTCCCG
CTGCCGTTCACCTATCCGCCGTTTGCGGCTGTGGTCTTCTACCCGTTGCATTTGGTGCCG
TTCGGTCTGATCGCGCTGCTGTGGCAAGTAGTGACGATGGCCGCGCTCTACGGCGCGGTT
CGGATCAGCCAGCGCCTGATGGGGGGCACCGCTGAGACCGGTCATTTCGCCGCGATGTTA
TGGACGGCGATCGCCATCTGGATCGAGCCGTTGCGCAGCACCTTTGACTATGGGCAGATC
AACGTGCTGCTGATGCTGGCGGCGCTTTGGGCGGTCTACACCCCGCGGTGGTGGCTATCG
GGACTGCTGGTCGGGGTGGCCTCGGGTGTCAAGTTGACGCCGGCGATTACCGCTGTCTAC
CTCGTCGGCGTTCGGCGGTTGCATGCGGCCGCATTTTCGGTGGTCGTGTTCCTTGCCACC
GTCGGCGTGTCGCTACTGGTCGTCGGCGATGAAGCCCGCTACTACTTCACCGACCTGTTG
GGCGACGCAGGCCGGGTTGGGCCCATCGCCACCTCCTTCAATCAATCCTGGCGCGGCGCG
ATTTCCCGGATTCTCGGTCACGACGCCGGTTTTGGTCCGCTGGTTCTGGCTGCGATCGCC
AGTACGGCGGTATTGGCCATCCTGGCCTGGCGTGCGCTCGACAGGTCCGATCGGCTGGGC
AAACTATTGGTGGTCGAGTTGTTCGGCCTGCTGCTCTCGCCGATCTCCTGGACTCACCAC
TGGGTGTGGCTAGTGCCGCTGATGATCTGGCTGATTGACGGGCCAGCGCGTGAGCGCCCG
GGCGCCCGGATTTTGGGCTGGGGCTGGTTGGTGTTGACCATCGTCGGCGTGCCGTGGTTG
CTGAGCTTTGCTCAACCGAGCATCTGGCAAATCGGCCGGCCGTGGTATTTGGCCTGGGCC
GGTCTGGTCTACGTGGTGGCGACGCTGGCGACCTTGGGCTGGATCGCCGCCTCCGAGCGT
TACGTGCGCATTCGGCCGCGGCGCATGGCCAATTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift M. Stapleton, I. Haq et al. Mycobacterium tuberculosis cAMP receptor protein (Rv3676) differs from the Escherichia coli paradigm in its cAMP binding and DNA binding properties and transcription activation properties. J. Biol. Chem. 2010
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	RegulatedBy Rv3676	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Name	Polyprenol phosphomannose-dependent alpha-1,2-mannosyltransferase involved in polar PIM synthesis	active	mjackson	2012-10-05
	PIM, LM and LAM biosynthesis
Symbol	pimE	active	mjackson	2012-10-05
	PIM, LM and LAM biosynthesis
Name	Polyprenol phosphomannose-dependent alpha-1,2-mannosyltransferase involved in polar PIM synthesis	active	mjackson	2012-10-05
	PIM, LM and LAM biosynthesis
Symbol	pimE	active	mjackson	2012-10-05
	PIM, LM and LAM biosynthesis
Other	TBPWY:PIM, LM and LAM biosynthesis	active	mjackson	2012-03-05
	Polyprenol phosphomannose-dependent alpha-1,2-mannosyltransferase involved in polar PIM synthesis (phenotypic [mycobacterial recombinant strains]; enzymatic) authors,YS. Morita,CB. Sena,RF. Waller,K. Kurokawa,MF. Sernee,F. Nakatani,RE. Haites,H. Billman-Jacobe,MJ. McConville,Y. Maeda,T. Kinoshita PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of phosphatidylinositol mannoside in mycobacteria. J. Biol. Chem. 2006
Symbol	pimE	active	mjackson	2012-03-05
	Polyprenol phosphomannose-dependent alpha-1,2-mannosyltransferase involved in polar PIM synthesis (phenotypic [mycobacterial recombinant strains]; enzymatic) authors,YS. Morita,CB. Sena,RF. Waller,K. Kurokawa,MF. Sernee,F. Nakatani,RE. Haites,H. Billman-Jacobe,MJ. McConville,Y. Maeda,T. Kinoshita PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of phosphatidylinositol mannoside in mycobacteria. J. Biol. Chem. 2006