Rv1285 - sulfate adenylyltransferase subunit 2 cysD

Expression: Most Significant Conditions for Rv1285

Protein Domains

Gene Information
Locus	Rv1285
Symbol	cysD
Gene Name	sulfate adenylyltransferase subunit 2 cysD
Location	1437909 - 1438907 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:999 bp Protein:333 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	19497
Related Genes	Acel_1618 CE2641 cg3115 jk0246 MAP2485c MAV_1436 Mkms_3993 Mmcs_3919 MSMEG_4979 MT1323 MUL_3996 Mvan_4423 nfa24550 SAV2131
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1285
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1285 Transcript 1
MAITINMVNPTGFIRYEDVEQEAMTSDVTVGPAPGQYQLSHLRLLEAEAIHVIREVAAEF
ERPVLLFSGGKDSIVMLHLALKAFRPGRLPFPVMHVDTGHNFDEVIATRDELVAAAGVRL
VVASVQDDIDAGRVVETIPSRNPIQTVTLLRAIRENQFDAAFGGARRDEEKARAKERVFS
FRDEFGQWDPKAQRPELWNLYNGRHHKGEHIRVFPLSNWTEFDIWSYIGAEQVRLPSIYF
AHRRKVFQRDGMLLAVHRHMQPRADEPVFEATVRFRTVGDVTCTGCVESSASTVAEVIAE
TAVARLTERGATRADDRISEAGMEDRKRQGYF*

Genomic Sequence

>Rv1285
ATGGCAATAACCATAAATATGGTCAATCCTACCGGATTTATCAGGTATGAGGACGTGGAA
CAGGAAGCCATGACCAGCGATGTGACGGTGGGCCCCGCACCCGGCCAGTACCAACTGAGC
CATCTGCGCTTGCTGGAGGCCGAAGCCATCCACGTCATCCGGGAGGTGGCCGCCGAGTTC
GAGCGGCCAGTGCTGTTGTTCTCGGGGGGCAAGGACTCCATCGTCATGCTGCACCTGGCG
CTGAAGGCGTTTCGGCCCGGGCGACTGCCGTTCCCGGTCATGCACGTCGACACCGGTCAC
AACTTCGACGAAGTTATCGCTACCCGAGACGAGTTGGTCGCCGCGGCCGGGGTGCGGCTG
GTGGTGGCGTCGGTGCAGGACGATATCGATGCCGGTCGGGTCGTCGAGACCATCCCGTCG
CGAAATCCGATACAGACCGTGACGCTGCTGCGGGCCATCCGGGAGAACCAATTCGACGCG
GCATTCGGGGGAGCCCGGCGCGACGAGGAGAAGGCCCGCGCCAAGGAGCGGGTGTTCAGC
TTCCGCGACGAGTTCGGCCAGTGGGACCCGAAGGCTCAGCGGCCGGAACTGTGGAACCTC
TACAACGGACGGCACCACAAGGGCGAGCACATCCGGGTCTTCCCGCTGTCCAACTGGACC
GAATTCGACATCTGGTCCTACATCGGCGCCGAGCAGGTCAGGCTGCCGTCCATCTATTTC
GCCCACCGGCGCAAGGTGTTTCAGCGCGACGGCATGTTGCTGGCCGTGCACCGGCACATG
CAACCGCGAGCCGACGAGCCGGTGTTCGAGGCCACGGTGCGATTCCGCACCGTCGGGGAT
GTTACCTGCACCGGGTGCGTCGAGTCGTCGGCATCGACGGTCGCGGAAGTCATCGCCGAA
ACTGCGGTGGCCCGCTTGACGGAGCGCGGGGCGACCAGGGCTGACGACCGGATCTCGGAG
GCTGGAATGGAAGACCGCAAGCGGCAGGGATACTTCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	PhysicalInteraction Rv1286	active	priti.priety	2012-10-05
	Co-expression Analysis R. Pinto, QX. Tang et al. The Mycobacterium tuberculosis cysD and cysNC genes form a stress-induced operon that encodes a tri-functional sulfate-activating complex. Microbiology (Reading, Engl.) 2004
Interaction	PhysicalInteraction Rv1286	active	priti.priety	2012-10-05
	Co-expression Analysis authors,DP. Bhave,WB. Muse,KS. Carroll Drug targets in mycobacterial sulfur metabolism. Infect Disord Drug Targets 2007
Interaction	RegulatedBy Rv0757	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. SB. Walters, E. Dubnau et al. The Mycobacterium tuberculosis PhoPR two-component system regulates genes essential for virulence and complex lipid biosynthesis. Mol. Microbiol. 2006
Term	EC:2.7.7.4 Sulfate adenylyltransferase. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay R. Pinto, QX. Tang et al. The Mycobacterium tuberculosis cysD and cysNC genes form a stress-induced operon that encodes a tri-functional sulfate-activating complex. Microbiology (Reading, Engl.) 2004