Rv1349 - drugs-transport transmembrane ATP-binding protein ABC transporter
Protein Domains

Gene Information
LocusRv1349
Symbol
Gene Namedrugs-transport transmembrane ATP-binding protein ABC transporter
Location1515623 - 1517362 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:1740 bp
Protein:580 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number37898
Related GenesMAP2413c MAP2414c MAV_1566 MAV_1567 Mkms_4039 Mmcs_3965 MSMEG_5039 MT1390 MT1392 MUL_3901 MUL_3902 Mvan_4468 nfa46920 nfa46940 Rv1348
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
Search for regulators of Rv1349
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionPhysicalInteraction Rv2895cactiveshahanup862012-10-05
Co-expression (Functional linkage)
A. Farhana, S. Kumar et al. Mechanistic insights into a novel exporter-importer system of Mycobacterium tuberculosis unravel its role in trafficking of iron. PLoS ONE 2008
InteractionRegulatory Rv0288activeshahanup862012-10-05
Co-expression (Functional linkage)
authors,MS. Siegrist,M. Unnikrishnan,MJ. McConnell,M. Borowsky,TY. Cheng,N. Siddiqi,SM. Fortune,DB. Moody,EJ. Rubin Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition. Proc. Natl. Acad. Sci. U.S.A. 2009
InteractionRegulatory Rv0287activeshahanup862012-10-05
Co-expression (Functional linkage)
authors,MS. Siegrist,M. Unnikrishnan,MJ. McConnell,M. Borowsky,TY. Cheng,N. Siddiqi,SM. Fortune,DB. Moody,EJ. Rubin Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition. Proc. Natl. Acad. Sci. U.S.A. 2009
InteractionRegulatory Rv2711activeshahanup862012-10-05
Co-expression (Functional linkage)
GM. Rodriguez, MI. Voskuil et al. ideR, An essential gene in mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response. Infect. Immun. 2002
InteractionPhysicalInteraction Rv2895cactiveshahanup862012-10-05
Affinity purification (Physical interaction)
A. Farhana, S. Kumar et al. Mechanistic insights into a novel exporter-importer system of Mycobacterium tuberculosis unravel its role in trafficking of iron. PLoS ONE 2008
InteractionPhysicalInteraction Rv1348activeshahanup862012-10-05
Gene Neighborhood (Functional linkage)
GM. Rodriguez & I. Smith Identification of an ABC transporter required for iron acquisition and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2006
InteractionPhysicalInteraction Rv1348activeshahanup862012-10-05
Gene Neighborhood (Functional linkage)
MB. Ryndak,S. Wang,I. Smith,GM. Rodriguez The Mycobacterium tuberculosis high-affinity iron importer, IrtA, contains an FAD-binding domain. J. Bacteriol. 2010
InteractionPhysicalInteraction Rv1348activeshahanup862012-10-05
Gene Neighborhood (Functional linkage)
GM. Rodriguez & I. Smith Identification of an ABC transporter required for iron acquisition and virulence in Mycobacterium tuberculosis. J. Bacteriol. 2006
InteractionRegulatedBy Rv2711activeyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
GM. Rodriguez, MI. Voskuil et al. ideR, An essential gene in mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response. Infect. Immun. 2002