Rv1350 - 3-oxoacyl-[acyl-carrier protein] reductase fabG2
Protein Domains

Gene Information
LocusRv1350
SymbolfabG
Gene Name3-oxoacyl-[acyl-carrier protein] reductase fabG2
Location1517491 - 1518234 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:744 bp
Protein:248 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number37899
Related GenesMAP2408c MAV_1572 Mkms_1804 Mmcs_1757 MSMEG_2206 MT1393 MUL_3898 Mvan_1975
Transcriptional Regulation
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Regulatory Network
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Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
TermTBRXN:FAS140 fatty acid synthase (n-C14:0) - IDAactivenjamshidi2012-10-05
mtFABH (Rv0533c) - link between FAS I and FAS II - highest affinity for C12:0, see PMID: 10840036 (since FA synthesis is lumped, does not extend immediately to FAS II).
KH. Choi, L. Kremer et al. Identification and substrate specificity of beta -ketoacyl (acyl carrier protein) synthase III (mtFabH) from Mycobacterium tuberculosis. J. Biol. Chem. 2000
TermEC:2.3.1.85 Fatty-acid synthase. - IDAactivenjamshidi2012-10-05
mtFABH (Rv0533c) - link between FAS I and FAS II - highest affinity for C12:0, see PMID: 10840036 (since FA synthesis is lumped, does not extend immediately to FAS II).
KH. Choi, L. Kremer et al. Identification and substrate specificity of beta -ketoacyl (acyl carrier protein) synthase III (mtFabH) from Mycobacterium tuberculosis. J. Biol. Chem. 2000
NamePutative -Ketoacyl-ACP reductase/3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASEactivemjackson2012-10-05
FAS-II
SymbolfabG2activemjackson2012-10-05
FAS-II
TermEC:1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase. - NRactivejjmcfadden2012-03-05
Inferred from direct assay
K. Takayama, C. Wang et al. Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis. Clin. Microbiol. Rev. 2005
TermEC:2.3.1.41 Beta-ketoacyl-acyl-carrier-protein synthase I. - NRactivejjmcfadden2012-03-05
Inferred from direct assay
K. Takayama, C. Wang et al. Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis. Clin. Microbiol. Rev. 2005
TermEC:2.1.1.- Transferases. Transferring one-carbon groups. Methyltransferases. - NRactivejjmcfadden2012-03-05
Inferred from direct assay
K. Takayama, C. Wang et al. Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis. Clin. Microbiol. Rev. 2005