Rv1402 - primosomal protein N priA

Expression: Most Significant Conditions for Rv1402

Protein Domains

Gene Information
Locus	Rv1402
Symbol	priA
Gene Name	primosomal protein N priA
Location	1577613 - 1579580 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1968 bp Protein:656 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	689
Related Genes	Acel_1289 BL1791 CE1722 cg1805 DIP1324 jk1015 MAP1130 MAV_3375 Mkms_2427 ML0548 Mmcs_2380 MSMEG_3061 MT1446 MUL_1797 Mvan_2684 nfa36120 PPA1194 SAV6875
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1402
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1402 Transcript 1
MLSVPHLDRDFDYLVPAEHSDDAQPGVRVRVRFHGRLVDGFVLERRSDSDHHGKLGWLDR
VVSPEPVLTTEIRRLVDAVAARYAGTRQDVLRLAVPARHARVEREITTAPGRPVVAPVDP
SGWAAYGRGRQFLAALADSRAARAVWQALPGELWADRFAEAAAQTVRAGRTVLAIVPDQR
DLDTLWQAATALVDEHSVVALSAGLGPEARYRRWLAALRGSARLVIGTRSAVFAPLSELG
LVMVWADADDSLAEPRAPYPHAREVAMLRAHQARCAALIGGYARTAEAHALVRSGWAHDV
VAPRPEVRARSPRVVALDDSGYDDARDPAARTARLPSIALRAARSALQSGAPVLVQVPRR
GYIPSLACGRCRAIARCRSCTGPLSLQGAGSPGAVCRWCGRVDPTLRCVRCGSDVVRAVV
VGARRTAEELGRAFPGTAVITSAGDTLVPQLDAGPALVVATPGAEPRAPGGYGAALLLDS
WALLGRQDLRAAEDALWRWMTAAALVRPRGAGGVVTVVAESSIPTVQSLIRWDPVGHAEA
ELAARTEVGLPPSVHIAALDGPAGTVTALLEAARLPDPDRLQADLLGPVDLPPGVRRPAG
IPADAPVIRMLLRVCREQGLELAASLRRGIGVLSARQTRQTRSLVRVQIDPLHIG*

Genomic Sequence

>Rv1402
ATGTTGTCGGTGCCGCACCTGGACCGCGACTTCGACTACTTGGTGCCCGCCGAACACTCC
GACGATGCCCAGCCGGGGGTGCGGGTACGGGTGCGGTTTCACGGTCGGCTGGTCGACGGG
TTTGTCCTAGAGCGCCGCAGCGACAGCGATCACCACGGCAAGCTGGGCTGGCTGGATCGT
GTGGTGTCGCCCGAACCGGTGCTCACCACGGAGATCCGCCGGTTGGTCGATGCGGTGGCG
GCGCGCTACGCCGGGACCCGCCAGGACGTATTGCGGCTCGCAGTGCCCGCCCGGCACGCA
CGGGTGGAGCGGGAAATCACCACGGCCCCGGGTCGGCCGGTGGTAGCGCCGGTCGACCCG
TCGGGTTGGGCGGCCTACGGTCGCGGTCGGCAATTCCTGGCCGCGCTGGCCGACTCGCGC
GCTGCGCGGGCCGTTTGGCAGGCGCTACCGGGCGAGCTGTGGGCGGACCGATTCGCCGAG
GCTGCCGCGCAGACCGTACGTGCCGGGCGCACGGTACTGGCGATCGTGCCCGATCAGCGG
GATCTGGACACCCTGTGGCAGGCCGCGACGGCCCTCGTCGATGAGCACAGTGTGGTAGCA
CTGTCGGCCGGCCTGGGCCCGGAGGCACGCTATCGGCGCTGGCTGGCCGCGTTGCGGGGC
AGCGCGCGGCTGGTGATTGGCACCCGCAGCGCGGTGTTCGCGCCGTTGAGCGAGCTGGGC
CTGGTCATGGTCTGGGCCGACGCCGACGACTCCCTGGCTGAGCCGCGGGCACCCTATCCG
CACGCCCGTGAGGTGGCGATGCTGCGGGCGCATCAGGCGCGGTGCGCAGCGCTGATCGGC
GGCTACGCCCGCACGGCCGAGGCCCACGCGCTGGTGCGTAGCGGCTGGGCGCACGACGTG
GTTGCACCCCGGCCGGAGGTGCGTGCACGCTCTCCTCGCGTGGTTGCCCTCGACGACAGC
GGATACGACGACGCGCGAGACCCGGCCGCCCGCACCGCACGGCTACCGTCCATCGCGCTG
CGCGCCGCGCGCTCAGCGCTGCAGTCCGGGGCGCCGGTGCTGGTGCAGGTGCCGCGGCGC
GGGTACATCCCCTCGCTGGCCTGCGGGCGCTGCCGGGCGATCGCTCGTTGCCGGTCGTGC
ACGGGTCCGCTATCGCTGCAAGGCGCCGGCTCGCCCGGTGCGGTATGTCGCTGGTGTGGA
CGGGTGGACCCGACACTGCGATGCGTGCGCTGTGGGTCGGACGTGGTGCGTGCCGTGGTG
GTGGGGGCCCGGCGCACTGCCGAAGAGCTCGGCCGGGCATTCCCGGGTACGGCGGTGATT
ACGTCGGCCGGCGACACCCTGGTGCCCCAGCTCGACGCCGGCCCAGCCCTGGTGGTCGCC
ACTCCAGGAGCCGAACCCCGGGCGCCCGGCGGGTATGGGGCGGCGCTGCTGCTGGATAGC
TGGGCGCTGCTGGGCCGTCAAGACTTGCGCGCGGCCGAGGACGCGCTGTGGCGCTGGATG
ACGGCGGCCGCCCTGGTTCGGCCGCGCGGGGCGGGCGGTGTGGTGACCGTGGTCGCCGAA
TCGTCCATTCCGACAGTGCAATCGCTGATCCGGTGGGATCCGGTCGGTCACGCGGAGGCC
GAACTGGCAGCCCGAACCGAAGTCGGCCTGCCGCCAAGTGTGCACATCGCTGCTCTTGAC
GGCCCTGCCGGCACCGTGACGGCATTGCTGGAGGCGGCTCGGCTGCCCGACCCGGATCGC
CTCCAAGCCGATCTGCTGGGCCCGGTGGACCTGCCACCCGGCGTCCGTCGCCCGGCGGGC
ATCCCCGCCGATGCGCCGGTCATCAGGATGTTGCTGCGGGTGTGCCGCGAGCAGGGCCTG
GAGTTGGCGGCGAGTCTGCGGCGCGGCATCGGTGTGCTCAGTGCGCGGCAAACCCGGCAA
ACCCGTAGCCTGGTTCGGGTACAGATTGACCCGCTGCATATCGGGTAA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	PhysicalInteraction Rv2973c	active	shahanup86	2012-10-05
	Structural Analysis D. Schnappinger,S. Ehrt,MI. Voskuil,Y. Liu,JA. Mangan,IM. Monahan,G. Dolganov,B. Efron,PD. Butcher,C. Nathan,GK. Schoolnik Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment. J. Exp. Med. 2003
Interaction	PhysicalInteraction Rv2973c	active	shahanup86	2012-10-05
	Structural Analysis authors,P. McGlynn,AA. Mahdi,RG. Lloyd Characterisation of the catalytically active form of RecG helicase. Nucleic Acids Res. 2000
Interaction	PhysicalInteraction Rv2973c	active	shahanup86	2012-10-05
	Structural Analysis authors,ME. Robu,RB. Inman,MM. Cox Situational repair of replication forks: roles of RecG and RecA proteins. J. Biol. Chem. 2004
Interaction	PhysicalInteraction Rv2973c	active	shahanup86	2012-10-05
	Structural Analysis authors,AV. Gregg,P. McGlynn,RP. Jaktaji,RG. Lloyd Direct rescue of stalled DNA replication forks via the combined action of PriA and RecG helicase activities. Mol. Cell 2002
Interaction	PhysicalInteraction Rv2973c	active	shahanup86	2012-10-05
	Structural Analysis authors,MR. Singleton,S. Scaife,DB. Wigley Structural analysis of DNA replication fork reversal by RecG. Cell 2001
Interaction	PhysicalInteraction Rv2973c	active	shahanup86	2012-10-05
	Structural Analysis authors,GJ. Sharples,SM. Ingleston,RG. Lloyd Holliday junction processing in bacteria: insights from the evolutionary conservation of RuvABC, RecG, and RusA. J. Bacteriol. 1999
Interaction	PhysicalInteraction Rv2973c	active	shahanup86	2012-10-05
	Spectrophotometric D. Schnappinger,S. Ehrt,MI. Voskuil,Y. Liu,JA. Mangan,IM. Monahan,G. Dolganov,B. Efron,PD. Butcher,C. Nathan,GK. Schoolnik Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment. J. Exp. Med. 2003
Interaction	PhysicalInteraction Rv2973c	active	shahanup86	2012-10-05
	Spectrophotometric authors,P. McGlynn,AA. Mahdi,RG. Lloyd Characterisation of the catalytically active form of RecG helicase. Nucleic Acids Res. 2000
Interaction	PhysicalInteraction Rv2973c	active	shahanup86	2012-10-05
	Spectrophotometric authors,ME. Robu,RB. Inman,MM. Cox Situational repair of replication forks: roles of RecG and RecA proteins. J. Biol. Chem. 2004
Interaction	PhysicalInteraction Rv2973c	active	shahanup86	2012-10-05
	Spectrophotometric authors,AV. Gregg,P. McGlynn,RP. Jaktaji,RG. Lloyd Direct rescue of stalled DNA replication forks via the combined action of PriA and RecG helicase activities. Mol. Cell 2002
Interaction	PhysicalInteraction Rv2973c	active	shahanup86	2012-10-05
	Spectrophotometric authors,MR. Singleton,S. Scaife,DB. Wigley Structural analysis of DNA replication fork reversal by RecG. Cell 2001
Interaction	PhysicalInteraction Rv2973c	active	shahanup86	2012-10-05
	Spectrophotometric authors,GJ. Sharples,SM. Ingleston,RG. Lloyd Holliday junction processing in bacteria: insights from the evolutionary conservation of RuvABC, RecG, and RusA. J. Bacteriol. 1999