Rv1537 - DNA polymerase IV dinX

Expression: Most Significant Conditions for Rv1537

Protein Domains

Gene Information
Locus	Rv1537
Symbol	dinX
Gene Name	DNA polymerase IV dinX
Location	1739856 - 1741247 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1392 bp Protein:464 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	32873
Related Genes	Acel_1444 BL1565 CE2040 cg2355 DIP1588 jk0761 MAP1248 MAV_3232 Mkms_3155 Mmcs_3095 MSMEG_3172 MT1589 MUL_1535 Mvan_2771 nfa17790 PPA1670 SAV6985
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1537
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1537 Transcript 1
MLHLDMDAFFASVEQLTRPTLRGRPVLVGGLGGRGVVAGASYEARAYGARSAMPMHQARR
LIGVTAVVLPPRGVVYGIASRRVFDTVRGLVPVVEQLSFDEAFAEPPQLAGAVAEDVETF
CERLRRRVRDETGLIASVGAGSGKQIAKIASGLAKPDGIRVVRHAEEQALLSGLPVRRLW
GIGPVAEEKLHRLGIETIGQLAALSDAEAANILGATIGPALHRLARGIDDRPVVERAEAK
QISAESTFAVDLTTMEQLHEAIDSIAEHAHQRLLRDGRGARTITVKLKKSDMSTLTRSAT
MPYPTTDAGALFTVARRLLPDPLQIGPIRLLGVGFSGLSDIRQESLFADSDLTQETAAAH
YVETPGAVVPAAHDATMWRVGDDVAHPELGHGWVQGAGHGVVTVRFETRGSGPGSARTFP
VDTGDISNASPLDSLDWPDYIGQLSVEGSAGASAPTVDDVGDR*

Genomic Sequence

>Rv1537
GTGCTGCACCTGGACATGGATGCGTTTTTCGCCTCGGTCGAACAGCTCACCCGGCCGACC
CTGCGGGGGCGGCCGGTGCTGGTTGGCGGGCTGGGTGGGCGAGGTGTGGTGGCCGGCGCG
AGCTATGAAGCGCGGGCCTACGGTGCCCGATCGGCCATGCCGATGCATCAGGCCCGCAGG
CTGATCGGGGTGACGGCCGTGGTGTTGCCGCCACGCGGGGTGGTGTACGGGATCGCCAGC
CGCCGGGTATTCGACACCGTGCGCGGCCTGGTGCCCGTCGTCGAACAGCTTTCTTTCGAT
GAAGCGTTCGCCGAACCGCCCCAACTCGCCGGGGCAGTGGCCGAGGACGTCGAGACGTTC
TGCGAACGGTTGCGGCGACGGGTGCGCGACGAGACCGGCCTGATTGCCTCGGTCGGAGCG
GGCTCGGGCAAGCAGATCGCCAAGATTGCTTCTGGTCTGGCCAAACCCGACGGCATTCGG
GTAGTCCGGCACGCTGAAGAGCAAGCGCTTCTCAGCGGATTGCCGGTACGACGGCTGTGG
GGCATCGGCCCGGTCGCCGAGGAAAAGCTGCATCGGCTCGGCATCGAGACGATCGGGCAG
CTGGCCGCGCTGAGCGATGCCGAGGCGGCCAACATCCTAGGCGCGACGATTGGGCCCGCG
CTGCACCGGCTGGCCCGTGGCATCGACGACCGCCCAGTGGTGGAGCGCGCCGAAGCCAAG
CAAATCAGCGCCGAGTCCACGTTCGCCGTCGATCTGACCACCATGGAGCAATTGCACGAG
GCGATCGACTCCATCGCTGAGCACGCGCACCAACGCCTGCTGCGCGACGGCCGCGGCGCC
CGCACCATCACGGTGAAGCTAAAGAAATCCGACATGAGCACGCTAACCCGCTCGGCGACG
ATGCCCTACCCGACGACCGACGCCGGCGCGCTGTTTACGGTGGCCCGCCGGCTGCTGCCG
GATCCACTGCAAATCGGGCCAATTCGTCTTCTGGGTGTTGGGTTTTCGGGTTTGAGCGAC
ATTCGCCAGGAGTCGTTGTTTGCCGACTCGGACTTGACGCAGGAAACGGCGGCAGCGCAT
TACGTCGAAACACCGGGAGCGGTCGTGCCGGCCGCGCACGACGCCACGATGTGGCGGGTC
GGCGATGACGTCGCCCACCCTGAGCTTGGGCACGGCTGGGTGCAGGGAGCGGGCCACGGC
GTGGTCACCGTGCGGTTCGAAACGCGTGGTTCAGGCCCGGGCTCGGCGCGGACGTTCCCC
GTCGACACCGGCGACATCAGCAACGCCAGCCCGCTTGACAGCTTGGACTGGCCGGACTAC
ATCGGCCAGCTATCGGTCGAGGGGTCCGCCGGCGCCTCAGCCCCAACGGTCGATGACGTC
GGCGACCGGTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Other	TBPWY:Translesion synthesis	active	vmizrahi	2012-03-05
	Mutant had no effect on susceptibility to compounds that form N(2)-dG adducts and alkylating agents; no effect on mutation to rifampin resistance or on growth or survival in macrophages or mice
Symbol	dinB1	active	vmizrahi	2012-03-05
	Mutant had no effect on susceptibility to compounds that form N(2)-dG adducts and alkylating agents; no effect on mutation to rifampin resistance or on growth or survival in macrophages or mice