Rv1595 - L-aspartate oxidase nadB

Expression: Most Significant Conditions for Rv1595

Protein Domains

Gene Information
Locus	Rv1595
Symbol	nadB
Gene Name	L-aspartate oxidase nadB
Location	1795805 - 1797388 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1584 bp Protein:528 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	33683
Related Genes	Acel_0213 BL1375 DIP2258 MAP1290 MAV_3190 Mkms_3127 ML1226 Mmcs_3067 MSMEG_3200 MT1631 MUL_1569 Mvan_2799 nfa18380 SAV4688
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1595
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1595 Transcript 1
MAGPAWRDAADVVVIGTGVAGLAAALAADRAGRSVVVLSKAAQTHVTATHYAQGGIAVVL
PDNDDSVDAHVADTLAAGAGLCDPDAVYSIVADGYRAVTDLVGAGARLDESVPGRWALTR
EGGHSRRRIVHAGGDATGAEVQRALQDAAGMLDIRTGHVALRVLHDGTAVTGLLVVRPDG
CGIISAPSVILATGGLGHLYSATTNPAGSTGDGIALGLWAGVAVSDLEFIQFHPTMLFAG
RAGGRRPLITEAIRGEGAILVDRQGNSITAGVHPMGDLAPRDVVAAAIDARLKATGDPCV
YLDARGIEGFASRFPTVTASCRAAGIDPVRQPIPVVPGAHYSCGGIVTDVYGQTELLGLY
AAGEVARTGLHGANRLASNSLLEGLVVGGRAGKAAAAHAAAAGRSRATSSATWPEPISYT
ALDRGDLQRAMSRDASMYRAAAGLHRLCDSLSGAQVRDVACRRDFEDVALTLVAQSVTAA
ALARTESRGCHHRAEYPCTVPEQARSIVVRGADDANAVCVQALVAVC*

Genomic Sequence

>Rv1595
ATGGCCGGTCCCGCTTGGCGGGATGCGGCCGATGTTGTCGTGATCGGCACGGGCGTTGCC
GGGCTGGCGGCGGCATTGGCCGCCGATCGCGCCGGGCGCAGCGTCGTGGTGCTCAGCAAG
GCTGCCCAGACGCACGTGACCGCGACACACTACGCGCAAGGCGGTATCGCGGTGGTGCTG
CCGGACAACGACGACTCGGTCGACGCTCACGTCGCGGACACCTTGGCCGCAGGCGCGGGC
CTATGCGATCCCGATGCGGTGTACTCGATCGTCGCCGACGGCTACCGAGCGGTTACCGAT
TTGGTCGGAGCTGGGGCACGGTTGGATGAATCGGTCCCGGGCCGTTGGGCGTTGACGCGC
GAAGGCGGGCACTCGCGGCGACGCATCGTGCACGCGGGTGGCGACGCGACCGGCGCCGAG
GTTCAGCGGGCGCTCCAGGATGCCGCCGGGATGCTCGATATCCGCACCGGCCACGTGGCG
TTGCGAGTGCTGCACGACGGTACCGCGGTGACCGGGCTATTAGTGGTCAGACCGGACGGA
TGCGGCATTATCAGCGCTCCGTCGGTGATCCTGGCCACCGGCGGGCTCGGGCACCTGTAC
AGCGCGACCACCAATCCGGCGGGCTCCACCGGCGACGGCATCGCCCTGGGATTGTGGGCG
GGCGTCGCGGTCAGCGATCTCGAGTTCATCCAGTTCCACCCCACGATGCTTTTTGCCGGA
CGCGCCGGGGGTCGGCGGCCGCTGATCACCGAGGCCATCCGCGGCGAGGGTGCGATCTTG
GTGGACAGGCAAGGCAATTCGATAACGGCAGGCGTGCATCCGATGGGTGATTTGGCGCCG
CGCGACGTCGTCGCCGCCGCCATCGACGCGCGGCTGAAGGCCACCGGCGATCCGTGCGTC
TACCTCGACGCCCGCGGCATCGAGGGCTTCGCGTCCCGGTTCCCGACAGTCACGGCATCC
TGCCGGGCTGCCGGCATTGACCCCGTCCGGCAACCGATCCCGGTTGTTCCCGGTGCGCAC
TACAGCTGCGGCGGCATAGTGACCGATGTGTACGGCCAGACCGAGCTGCTCGGGTTGTAC
GCCGCTGGCGAGGTGGCCCGCACCGGGTTGCACGGCGCCAACCGCCTGGCCTCCAACAGC
TTGCTAGAGGGTTTGGTGGTGGGCGGCCGCGCCGGAAAGGCCGCCGCCGCCCACGCCGCG
GCGGCCGGGCGTTCGCGTGCGACCTCGTCAGCGACCTGGCCCGAACCGATCAGCTACACC
GCACTGGACCGCGGCGACCTGCAACGGGCGATGAGCCGGGACGCGTCGATGTACCGCGCC
GCCGCCGGGCTGCACCGGCTGTGCGACAGCCTATCCGGAGCACAGGTTCGCGACGTGGCT
TGTCGCCGCGATTTCGAGGACGTGGCGCTCACGCTGGTCGCGCAGAGCGTGACCGCCGCC
GCCTTGGCCCGCACCGAAAGCCGTGGCTGCCATCATCGCGCGGAGTACCCGTGCACCGTG
CCGGAGCAGGCACGCAGCATCGTGGTCCGGGGAGCCGACGACGCAAATGCGGTGTGTGTC
CAGGCGCTAGTGGCGGTGTGCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	PhysicalInteraction Rv1596	active	shahanup86	2012-10-05
	Operon (Functional linkage) authors,V. Sharma,C. Grubmeyer,JC. Sacchettini Crystal structure of quinolinic acid phosphoribosyltransferase from Mmycobacterium tuberculosis: a potential TB drug target. Structure 1998
Interaction	PhysicalInteraction Rv1596	active	shahanup86	2012-10-05
	Operon (Functional linkage) authors,V. Sharma,C. Grubmeyer,JC. Sacchettini Crystal structure of quinolinic acid phosphoribosyltransferase from Mmycobacterium tuberculosis: a potential TB drug target. Structure 1998
Interaction	PhysicalInteraction Rv1594	active	shahanup86	2012-10-05
	Operon (Functional linkage) authors,V. Sharma,C. Grubmeyer,JC. Sacchettini Crystal structure of quinolinic acid phosphoribosyltransferase from Mmycobacterium tuberculosis: a potential TB drug target. Structure 1998
Interaction	Regulatory Rv1221	active	shahanup86	2012-10-05
	Co-expression (Functional linkage) R. Manganelli, MI. Voskuil et al. The Mycobacterium tuberculosis ECF sigma factor sigmaE: role in global gene expression and survival in macrophages. Mol. Microbiol. 2001
Interaction	PhysicalInteraction Rv1594	active	shahanup86	2012-10-05
	Operon (Functional linkage) authors,V. Sharma,C. Grubmeyer,JC. Sacchettini Crystal structure of quinolinic acid phosphoribosyltransferase from Mmycobacterium tuberculosis: a potential TB drug target. Structure 1998
Interaction	RegulatedBy Rv2710	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. JH. Lee, PC. Karakousis et al. Roles of SigB and SigF in the Mycobacterium tuberculosis sigma factor network. J. Bacteriol. 2008
Interaction	RegulatedBy Rv0212c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv0212c	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006