Rv1635c - conserved membrane protein

Expression: Most Significant Conditions for Rv1635c

Protein Domains

Gene Information
Locus	Rv1635c
Symbol
Gene Name	conserved membrane protein
Location	1840572 - 1842242 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1671 bp Protein:557 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	18848
Related Genes	MAP1338c MAV_3138 ML1389 MT1671 MUL_1618 SAV5089
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1635c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1635c Transcript 1
MHASRPGAPPHAGLPSRRTAGDQDHRADPKVTRIMSASTLEQPAAAHVDELVARMRGRLL
DPLAIAVLAAVISGAWASRPSLWFDEGATISASASRTLPELWSLLGHIDAVHGLYYLLMH
GWFAIFPPTELWSRLPSCLAIGAAAAGVVVFAKQFSGRTTAVCAGAVFAILPRVTWAGIE
ARSSALSVAAAVWLTVLLVAAVRCNTQRRWLLYALVLMLSILVSINLALLVPAYATMVPL
LASGKSRKSPVIWWTVVTAAALGAMTPFILFAHGQVWQVGWIAGLNRNIILDVIHRQYFD
HSVPFAILAGLIVAAGIAAHLAGARGPGGDTHRLVLVSAAWIVVPTAVVLIYSATVEPIY
YPRYLILTAPAAAVILAVCVVTIARKPWLIAGVVFLLAAAAFPNYFFTQRGPYAKEGWDY
SQVADVISAHAKPGDCLLVDNTAGWRPGPIRALLATRPAAFRSLIDVERGTYGPKVGTLW
DGHVAVWLTTAKIDKCPTLWTIANRDKSLPDHQVGEMLSPGTGFGRTPVYRFPSYLGFRI
VERWQFHYSQVVKSTR*

Genomic Sequence

>Rv1635c
ATGCATGCGAGTCGTCCCGGCGCACCGCCGCACGCCGGGCTGCCCAGTCGCCGAACCGCC
GGTGACCAGGATCATCGCGCGGACCCTAAGGTGACCCGCATCATGTCCGCCTCCACTCTG
GAGCAGCCCGCGGCAGCACACGTCGACGAGTTGGTGGCGCGGATGCGCGGCCGGCTGCTC
GACCCGCTGGCGATTGCAGTGCTGGCCGCGGTCATCAGCGGCGCCTGGGCAAGCAGGCCA
TCGTTGTGGTTCGACGAGGGGGCAACGATCTCGGCTTCAGCCAGCCGGACATTGCCAGAG
CTATGGAGTCTGCTGGGCCATATCGACGCCGTGCACGGCCTGTACTACCTGTTGATGCAT
GGCTGGTTCGCCATATTTCCGCCCACCGAATTATGGTCGCGGCTTCCCAGCTGCCTGGCC
ATTGGAGCGGCCGCCGCCGGCGTGGTGGTTTTTGCCAAACAGTTTTCGGGACGCACCACG
GCGGTGTGTGCGGGAGCCGTGTTCGCGATTCTGCCCAGGGTGACGTGGGCCGGAATCGAA
GCACGCTCCTCCGCGCTGTCGGTAGCAGCCGCCGTCTGGCTGACCGTATTACTCGTGGCC
GCGGTGCGGTGCAACACCCAGCGGCGGTGGCTGCTCTACGCGCTGGTTTTGATGCTGTCG
ATCTTGGTCAGTATCAACCTGGCCCTGTTGGTACCGGCCTATGCGACGATGGTGCCGCTG
CTGGCGTCCGGGAAATCACGCAAATCTCCCGTGATCTGGTGGACGGTCGTCACGGCAGCC
GCGCTCGGGGCCATGACACCGTTCATACTGTTCGCCCACGGCCAGGTTTGGCAGGTCGGG
TGGATCGCAGGGTTGAACAGAAACATCATTCTCGACGTCATACACCGCCAGTATTTCGAT
CACAGTGTTCCGTTCGCCATCCTCGCGGGCCTCATCGTCGCTGCCGGCATCGCGGCGCAT
CTGGCCGGAGCTCGTGGACCCGGTGGCGATACCCACCGGCTCGTGCTCGTCAGCGCAGCC
TGGATCGTCGTGCCCACCGCCGTCGTCCTCATCTACTCGGCGACCGTCGAACCGATCTAC
TACCCGCGCTACCTGATCCTCACCGCCCCCGCCGCGGCCGTCATCCTGGCGGTTTGCGTC
GTCACCATCGCCCGCAAGCCGTGGCTCATCGCCGGGGTCGTGTTTCTCCTTGCCGCCGCA
GCGTTTCCGAACTACTTCTTCACACAGCGGGGGCCGTACGCGAAAGAGGGCTGGGATTAC
AGCCAGGTGGCAGATGTCATCAGCGCCCATGCCAAGCCCGGGGATTGCCTGCTGGTGGAC
AACACCGCGGGTTGGCGACCCGGGCCCATCCGCGCCCTGCTGGCCACCCGGCCGGCGGCG
TTCCGGTCGCTGATTGACGTCGAGCGCGGCACCTACGGCCCCAAGGTCGGCACTTTGTGG
GATGGCCATGTCGCTGTGTGGCTTACGACGGCCAAGATCGACAAGTGCCCCACGCTGTGG
ACGATAGCCAATCGTGACAAGTCGTTGCCCGATCATCAGGTCGGCGAAATGTTGTCACCG
GGAACAGGCTTCGGGCGCACGCCCGTATACCGGTTCCCGAGCTACCTCGGCTTCCGCATC
GTCGAGCGCTGGCAGTTCCACTACTCGCAGGTGGTCAAGTCAACGCGGTAA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Name	Polyprenol phosphomannose-dependent ManLAM-capping mannosyltransferase	active	mjackson	2012-10-05
	PIM, LM and LAM biosynthesis
Symbol	capA	active	mjackson	2012-10-05
	PIM, LM and LAM biosynthesis
Name	Polyprenol phosphomannose-dependent ManLAM-capping mannosyltransferase	active	mjackson	2012-10-05
	PIM, LM and LAM biosynthesis
Symbol	capA	active	mjackson	2012-10-05
	PIM, LM and LAM biosynthesis
Other	TBPWY:PIM, LM and LAM biosynthesis	active	mjackson	2012-03-05
	Polyprenol phosphomannose-dependent ManLAM-capping mannosyltransferase (phenotypic [mycobacterial recombinant strains]; enzymatic) authors,BJ. Appelmelk,J. den Dunnen,NN. Driessen,R. Ummels,M. Pak,J. Nigou,G. Larrouy-Maumus,SS. Gurcha,F. Movahedzadeh,J. Geurtsen,EJ. Brown,MM. Eysink Smeets,GS. Besra,PT. Willemsen,TL. Lowary,Y. van Kooyk,JJ. Maaskant,NG. Stoker,P. van der Ley,G. Puzo,CM. Vandenbroucke-Grauls,CW. Wieland,T. van der Poll,TB. Geijtenbeek,AM. van der Sar,W. Bitter The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction. Cell. Microbiol. 2008
Symbol	capA	active	mjackson	2012-03-05
	Polyprenol phosphomannose-dependent ManLAM-capping mannosyltransferase (phenotypic [mycobacterial recombinant strains]; enzymatic) authors,BJ. Appelmelk,J. den Dunnen,NN. Driessen,R. Ummels,M. Pak,J. Nigou,G. Larrouy-Maumus,SS. Gurcha,F. Movahedzadeh,J. Geurtsen,EJ. Brown,MM. Eysink Smeets,GS. Besra,PT. Willemsen,TL. Lowary,Y. van Kooyk,JJ. Maaskant,NG. Stoker,P. van der Ley,G. Puzo,CM. Vandenbroucke-Grauls,CW. Wieland,T. van der Poll,TB. Geijtenbeek,AM. van der Sar,W. Bitter The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction. Cell. Microbiol. 2008
Other	TBPWY:PIM, LM and LAM biosynthesis	active	mjackson	2012-03-05
	Polyprenol phosphomannose-dependent ManLAM-capping mannosyltransferase (phenotypic [mycobacterial recombinant strains]; enzymatic) authors,P. Dinadayala,D. Kaur,S. Berg,AG. Amin,VD. Vissa,D. Chatterjee,PJ. Brennan,DC. Crick Genetic basis for the synthesis of the immunomodulatory mannose caps of lipoarabinomannan in Mycobacterium tuberculosis. J. Biol. Chem. 2006
Symbol	capA	active	mjackson	2012-03-05
	Polyprenol phosphomannose-dependent ManLAM-capping mannosyltransferase (phenotypic [mycobacterial recombinant strains]; enzymatic) authors,P. Dinadayala,D. Kaur,S. Berg,AG. Amin,VD. Vissa,D. Chatterjee,PJ. Brennan,DC. Crick Genetic basis for the synthesis of the immunomodulatory mannose caps of lipoarabinomannan in Mycobacterium tuberculosis. J. Biol. Chem. 2006