Rv1659 - argininosuccinate lyase argH

Expression: Most Significant Conditions for Rv1659

Protein Domains

Gene Information
Locus	Rv1659
Symbol	argH
Gene Name	argininosuccinate lyase argH
Location	1872639 - 1874051 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1413 bp Protein:471 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	615
Related Genes	Acel_1256 BL1057 CE1533 cg1588 DIP1174 jk0848 MAP1368 MAV_3111 Mkms_3009 ML1413 Mmcs_2965 MSMEG_3769 MT1697 MUL_1651 Mvan_3307 nfa19630 PPA1346 SAV6779
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1659
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1659 Transcript 1
MSTNEGSLWGGRFAGGPSDALAALSKSTHFDWVLAPYDLTASRAHTMVLFRAGLLTEEQR
DGLLAGLDSLAQDVADGSFGPLVTDEDVHAALERGLIDRVGPDLGGRLRAGRSRNDQVAA
LFRMWLRDAVRRVATGVLDVVGALAEQAAAHPSAIMPGKTHLQSAQPILLAHHLLAHAHP
LLRDLDRIVDFDKRAAVSPYGSGALAGSSLGLDPDAIAADLGFSAAADNSVDATAARDFA
AEAAFVFAMIAVDLSRLAEDIIVWSSTEFGYVTLHDSWSTGSSIMPQKKNPDIAELARGK
SGRLIGNLAGLLATLKAQPLAYNRDLQEDKEPVFDSVAQLELLLPAMAGLVASLTFNVQR
MAELAPAGYTLATDLAEWLVRQGVPFRSAHEAAGAAVRAAEQRGVGLQELTDDELAAISP
ELTPQVREVLTIEGSVSARDCRGGTAPGRVAEQLNAIGEAAERLRRQLVR*

Genomic Sequence

>Rv1659
GTGAGCACCAACGAGGGGTCGCTGTGGGGCGGGCGGTTCGCCGGCGGCCCGTCCGACGCG
CTGGCCGCGCTGAGCAAGTCCACCCACTTCGACTGGGTGCTGGCCCCCTACGACCTCACC
GCGTCGCGGGCGCACACCATGGTGCTGTTTCGGGCCGGGCTGCTCACCGAGGAGCAACGC
GACGGGCTGCTCGCCGGCCTGGACAGCCTCGCCCAAGACGTCGCCGACGGCAGCTTCGGC
CCGCTGGTCACCGACGAGGACGTGCATGCCGCGCTGGAGCGGGGCCTGATCGACCGGGTC
GGACCGGACCTGGGCGGCCGACTGCGGGCCGGGCGCTCGCGCAACGACCAGGTGGCCGCG
CTGTTTCGGATGTGGCTGCGCGACGCGGTGCGCCGGGTCGCCACCGGTGTGCTCGACGTG
GTCGGTGCGCTGGCAGAGCAGGCCGCCGCACACCCGAGCGCCATCATGCCCGGCAAAACC
CACCTGCAGTCCGCCCAGCCGATCCTGCTGGCACACCATCTGCTCGCGCACGCCCACCCC
CTGCTGCGCGACCTGGACCGCATCGTCGACTTCGACAAACGCGCGGCGGTGTCCCCGTAC
GGCTCGGGCGCCTTGGCCGGCTCGTCGCTGGGCCTGGATCCCGACGCGATCGCCGCGGAC
CTCGGTTTCTCGGCTGCCGCGGACAACTCCGTCGACGCGACCGCCGCCCGCGACTTCGCC
GCCGAGGCGGCGTTCGTGTTCGCCATGATCGCCGTCGACCTGTCCCGGCTGGCTGAGGAC
ATCATCGTCTGGAGCTCGACGGAATTCGGCTACGTCACGTTGCATGACTCGTGGTCCACC
GGTAGCTCGATCATGCCGCAGAAGAAGAATCCGGACATCGCCGAGCTGGCCCGCGGCAAG
TCCGGGCGGCTGATCGGAAACCTGGCCGGGCTGCTGGCCACCCTGAAAGCCCAGCCCCTG
GCCTACAACCGCGACCTGCAGGAAGACAAGGAGCCGGTGTTCGATTCGGTGGCCCAGCTG
GAGCTGCTGCTGCCGGCGATGGCCGGGCTGGTGGCCAGCCTGACCTTCAATGTCCAGCGG
ATGGCGGAGCTGGCCCCGGCCGGCTATACGTTGGCCACCGATCTCGCCGAATGGCTTGTG
CGGCAAGGTGTTCCGTTTAGGTCCGCGCATGAGGCCGCGGGTGCGGCGGTGCGTGCGGCC
GAACAGCGCGGCGTGGGGCTGCAGGAACTCACCGACGACGAGCTGGCCGCCATCAGCCCC
GAGCTGACCCCGCAAGTCCGCGAGGTGCTGACCATCGAAGGCTCGGTGTCGGCCCGCGAT
TGCCGGGGTGGCACCGCGCCGGGCCGGGTTGCCGAGCAACTGAACGCCATTGGTGAAGCC
GCCGAGCGGCTGCGCCGCCAGCTGGTGCGCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv1657	active	ashwinigbhat	2012-10-05
	KS. Makarova, AA. Mironov et al. Conservation of the binding site for the arginine repressor in all bacterial lineages. Genome Biol. 2001
Interaction	Regulatory Rv1657	active	priti.priety	2012-10-05
	KS. Makarova, AA. Mironov et al. Conservation of the binding site for the arginine repressor in all bacterial lineages. Genome Biol. 2001
Interaction	RegulatedBy Rv1657	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
Interaction	RegulatedBy Rv1657	active	yamir.moreno	2012-10-05
	E.coli orthology based inference. Orthologous pair regulator-target found in E.coli. authors,M. Madan Babu,SA. Teichmann,L. Aravind Evolutionary dynamics of prokaryotic transcriptional regulatory networks. J. Mol. Biol. 2006
Term	EC:4.3.2.1 Argininosuccinate lyase. - NR	active	jjmcfadden	2012-03-05
	Inferred from direct assay authors,F. Flett,J. Platt,J. Cullum DNA rearrangements associated with instability of an arginine gene in Streptomyces coelicolor A3(2). J. Basic Microbiol. 1987