Rv1746 - anchored-membrane serine/threonine-protein kinase pknF
Protein Domains

Gene Information
LocusRv1746
SymbolpknF
Gene Nameanchored-membrane serine/threonine-protein kinase pknF
Location1972138 - 1973568 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:1431 bp
Protein:477 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number37687
Related GenesMAP1332 MAV_3145 MT1788
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
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Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionSignaling Rv1747activeaparna.vchalam2012-10-05
Yeast two-hybrid (Physical interaction)
V. Molle, D. Soulat et al. Two FHA domains on an ABC transporter, Rv1747, mediate its phosphorylation by PknF, a Ser/Thr protein kinase from Mycobacterium tuberculosis. FEMS Microbiol. Lett. 2004
InteractionSignaling Rv1747activeaparna.vchalam2012-10-05
Yeast two-hybrid (Physical interaction)
JM. Curry, R. Whalan et al. An ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in mice. Infect. Immun. 2005
InteractionSignaling Rv1747activepriyadarshinipriyanka20012012-10-05
Yeast two-hybrid (Physical interaction)
V. Molle, D. Soulat et al. Two FHA domains on an ABC transporter, Rv1747, mediate its phosphorylation by PknF, a Ser/Thr protein kinase from Mycobacterium tuberculosis. FEMS Microbiol. Lett. 2004
InteractionSignaling Rv1747activepriyadarshinipriyanka20012012-10-05
Yeast two-hybrid (Physical interaction)
JM. Curry, R. Whalan et al. An ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in mice. Infect. Immun. 2005
InteractionSignaling Rv1747activeaparna.vchalam2012-10-05
Yeast two-hybrid (Physical interaction)
P. Deol, R. Vohra et al. Role of Mycobacterium tuberculosis Ser/Thr kinase PknF: implications in glucose transport and cell division. J. Bacteriol. 2005
InteractionSignaling Rv1747activeaparna.vchalam2012-10-05
Yeast two-hybrid (Physical interaction)
V. Molle, D. Soulat et al. Two FHA domains on an ABC transporter, Rv1747, mediate its phosphorylation by PknF, a Ser/Thr protein kinase from Mycobacterium tuberculosis. FEMS Microbiol. Lett. 2004
InteractionSignaling Rv1747activepriyadarshinipriyanka20012012-10-05
Yeast two-hybrid (Physical interaction)
P. Deol, R. Vohra et al. Role of Mycobacterium tuberculosis Ser/Thr kinase PknF: implications in glucose transport and cell division. J. Bacteriol. 2005
InteractionSignaling Rv1747activepriyadarshinipriyanka20012012-10-05
Yeast two-hybrid (Physical interaction)
V. Molle, D. Soulat et al. Two FHA domains on an ABC transporter, Rv1747, mediate its phosphorylation by PknF, a Ser/Thr protein kinase from Mycobacterium tuberculosis. FEMS Microbiol. Lett. 2004
InteractionSignaling Rv0020cactivevmevada1022012-10-05
Affinity purification (Physical interaction)
C. Grundner, LM. Gay et al. Mycobacterium tuberculosis serine/threonine kinases PknB, PknD, PknE, and PknF phosphorylate multiple FHA domains. Protein Sci. 2005
NameTRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE, known to phosphorylate FabH, and InhA (not as well as PknA and PknB), KasA, KasBactivemjackson2012-10-05
Regulatory proteins