Rv1916 - isocitrate lyase aceAb


Protein Domains

Gene Information
LocusRv1916
SymbolaceAb
Gene Nameisocitrate lyase aceAb
Location2161566 - 2162762 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:1197 bp
Protein:399 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number19555
Related GenesMAP1643 MAV_2781 Mkms_0196 ML1985 Mmcs_0187 MSMEG_3706 MT1966 MUL_2943 Mvan_2977 SAV3429
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
Search for regulators of Rv1916
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
TermTBRXN:ICL Isocitrate lyase - ISSactivenjamshidi2012-10-05
PMID: 10932251
V. Sharma, S. Sharma et al. Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis. Nat. Struct. Biol. 2000
TermEC:4.1.3.1 Isocitrate lyase. - ISSactivenjamshidi2012-10-05
PMID: 10932251
V. Sharma, S. Sharma et al. Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis. Nat. Struct. Biol. 2000
TermTBRXN:ICL Isocitrate lyase - IDAactivenjamshidi2012-10-05
PMID: 10932251
V. Sharma, S. Sharma et al. Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis. Nat. Struct. Biol. 2000
TermEC:4.1.3.1 Isocitrate lyase. - IDAactivenjamshidi2012-10-05
PMID: 10932251
V. Sharma, S. Sharma et al. Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis. Nat. Struct. Biol. 2000
InteractionRegulatedBy Rv3286cactiveyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
EP. Williams, JH. Lee et al. Mycobacterium tuberculosis SigF regulates genes encoding cell wall-associated proteins and directly regulates the transcriptional regulatory gene phoY1. J. Bacteriol. 2007
TermEC:4.1.3.1 Isocitrate lyase. - NRactiveextern:JZUCKER2012-03-06
Inferred from mutant phenotype
K. Höner Zu Bentrup, A. Miczak et al. Characterization of activity and expression of isocitrate lyase in Mycobacterium avium and Mycobacterium tuberculosis. J. Bacteriol. 1999
TermEC:4.1.3.30 Methylisocitrate lyase. - NRactiveextern:JZUCKER2012-03-06
Inferred from mutant phenotype
K. Höner Zu Bentrup, A. Miczak et al. Characterization of activity and expression of isocitrate lyase in Mycobacterium avium and Mycobacterium tuberculosis. J. Bacteriol. 1999
TermEC:4.1.3.1 Isocitrate lyase. - NRactiveextern:JZUCKER2012-03-06
Traceable author statement to experimental support
authors,KY. Rhee,LP. de Carvalho,R. Bryk,S. Ehrt,J. Marrero,SW. Park,D. Schnappinger,A. Venugopal,C. Nathan Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. Trends Microbiol. 2011
TermEC:4.1.3.30 Methylisocitrate lyase. - NRactiveextern:JZUCKER2012-03-06
Traceable author statement to experimental support
authors,KY. Rhee,LP. de Carvalho,R. Bryk,S. Ehrt,J. Marrero,SW. Park,D. Schnappinger,A. Venugopal,C. Nathan Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. Trends Microbiol. 2011