Rv1976c - conserved hypothetical protein

Expression: Most Significant Conditions for Rv1976c

Protein Domains

Gene Information
Locus	Rv1976c
Symbol
Gene Name	conserved hypothetical protein
Location	2218844 - 2219251 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:408 bp Protein:136 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	2478
Related Genes	MAP1655c MAV_2768 Mkms_2062 ML1791 Mmcs_2016 MSMEG_3467 MT2028 Mvan_2002 SAV2241
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv1976c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv1976c Transcript 1
MRWIVDGMNVIGSRPDGWWRDRHRAMVMLVERLEGWAITKARGDDVTVVFERPPSTAIPS
SVVEVAHAPKAAANSADDEIVRLVRSGAQPQEIRVVTSDKALTDRVRDLGAAVYPAERFR
DLIDPRGSNAARRTQ*

Genomic Sequence

>Rv1976c
GTGCGGTGGATTGTCGACGGTATGAACGTGATCGGAAGTCGTCCGGATGGTTGGTGGCGC
GACCGCCATCGCGCGATGGTGATGCTGGTGGAAAGGCTCGAGGGGTGGGCCATCACCAAG
GCTCGGGGCGACGACGTGACGGTGGTGTTCGAGCGGCCGCCGTCGACCGCCATCCCGTCA
TCGGTGGTCGAAGTGGCGCATGCGCCCAAGGCGGCCGCCAACTCGGCCGACGACGAGATC
GTCCGGCTGGTCCGATCCGGCGCCCAGCCACAAGAGATTCGTGTGGTGACATCGGACAAA
GCGTTGACCGACCGGGTCCGAGACTTGGGTGCGGCAGTCTACCCGGCAGAACGGTTCCGT
GACCTTATCGACCCGCGCGGGTCGAACGCGGCCCGCCGCACGCAGTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift M. Stapleton, I. Haq et al. Mycobacterium tuberculosis cAMP receptor protein (Rv3676) differs from the Escherichia coli paradigm in its cAMP binding and DNA binding properties and transcription activation properties. J. Biol. Chem. 2010
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	ActivatedBy Rv1975	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression authors,MC. Garcia-Pelayo,KC. Caimi,JK. Inwald,J. Hinds,F. Bigi,MI. Romano,D. van Soolingen,RG. Hewinson,A. Cataldi,SV. Gordon Microarray analysis of Mycobacterium microti reveals deletion of genes encoding PE-PPE proteins and ESAT-6 family antigens. Tuberculosis (Edinb) 2004
Interaction	RegulatedBy Rv3676	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008