Rv2003c - conserved hypothetical protein

Expression: Most Significant Conditions for Rv2003c

Protein Domains

Gene Information
Locus	Rv2003c
Symbol
Gene Name	conserved hypothetical protein
Location	2248563 - 2249420 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:858 bp Protein:286 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	12739
Related Genes	Acel_1780 MT2059
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2003c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2003c Transcript 1
MVKRSRATRLSPSIWSGWESPQCRSIRARLLLPRGRSRPPNADCCWNQLAVTPDTRMPAS
SAAGRDAAAYDAWYDSPTGRPILATEVAALRPLIEVFAQPRLEIGVGTGRFADLLGVRFG
LDPSRDALMFARRRGVLVANAVGEAVPFVSRHFGAVLMAFTLCFVTDPAAIFRETRRLLA
DGGGLVIGFLPRGTPWADLYALRAARGQPGYRDARFYTAAELEQLLADSGFRVIARRCTL
HQPPGLARYDIEAAHDGIQAGAGFVAISAVDQAHEPKDDHPLESE*

Genomic Sequence

>Rv2003c
GTGGTCAAGCGCTCTCGGGCAACCCGACTTTCGCCGAGCATCTGGTCCGGATGGGAATCA
CCTCAGTGTCGGTCCATTCGGGCGCGATTGCTGCTACCCCGGGGTCGGTCGCGGCCGCCG
AACGCCGATTGTTGCTGGAATCAGCTCGCGGTGACGCCTGACACCCGGATGCCGGCATCG
TCGGCCGCCGGGCGCGACGCGGCGGCCTACGACGCCTGGTATGACTCACCCACCGGGCGG
CCGATCCTGGCGACCGAGGTCGCCGCGTTGCGGCCGCTCATCGAGGTCTTTGCCCAGCCA
CGCTTGGAAATCGGTGTCGGTACAGGACGTTTCGCCGACCTGCTCGGCGTGCGGTTCGGA
CTCGATCCATCCCGTGATGCGCTGATGTTCGCACGCCGGCGCGGCGTCCTGGTCGCCAAT
GCCGTCGGCGAGGCGGTCCCTTTCGTCAGCCGGCACTTCGGGGCGGTCCTCATGGCATTC
ACGCTCTGTTTCGTCACCGACCCGGCCGCCATATTCCGGGAAACGCGGCGTCTGCTCGCC
GACGGCGGCGGCCTTGTTATCGGGTTCTTGCCTCGCGGGACACCGTGGGCCGACCTGTAC
GCTCTGCGCGCGGCCCGCGGACAGCCAGGCTACCGCGACGCCCGCTTCTACACCGCGGCC
GAACTCGAACAACTGCTCGCAGACTCGGGATTCCGGGTCATCGCCCGCCGCTGCACGCTG
CACCAACCGCCGGGACTCGCCCGGTACGACATCGAAGCCGCCCATGACGGTATCCAAGCC
GGCGCCGGCTTCGTTGCTATCTCGGCGGTCGACCAAGCGCACGAGCCTAAGGATGATCAC
CCACTCGAGTCGGAATAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv3133c	active	shahanup86	2012-10-05
	coexpression(Functional Linkage) authors,J. Bacon,BW. James,L. Wernisch,A. Williams,KA. Morley,GJ. Hatch,JA. Mangan,J. Hinds,NG. Stoker,PD. Butcher,PD. Marsh The influence of reduced oxygen availability on pathogenicity and gene expression in Mycobacterium tuberculosis. Tuberculosis (Edinb) 2004
Interaction	RegulatedBy Rv3133c	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. HD. Park, KM. Guinn et al. Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis. Mol. Microbiol. 2003