Rv2004c - conserved hypothetical protein

Expression: Most Significant Conditions for Rv2004c

Protein Domains

Gene Information
Locus	Rv2004c
Symbol
Gene Name	conserved hypothetical protein
Location	2249478 - 2250974 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1497 bp Protein:499 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	2459
Related Genes	MAP2082 Mkms_1090 Mmcs_1074 MSMEG_3942 MT2060 Mvan_1384
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2004c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2004c Transcript 1
MDSPTNDGTCDAHPVTDEPFIDVRETHTAVVVLAGDRAFKAKKPVVTDFCDFRTAEQRER
ACIREFELNSRLAAQSYLGIAHLSDPSGGHAEPVVVMRRYRDKQRLASMVTAGLPVEGAL
DAIAEVLARFHQRAQRNRCIDTQGEVGAVARRWHENLAELRHHADKVVSGDVIRRIEHMV
DEFVSGREVLFAGRIKEGCIVDGHADLLADDIFLVDGEPALLDCLEFEDELRYLDRIDDA
AFLAMDLEFLGRKDLGDYFLAGYAVRSGDTAPASLRDFYIAYRAVVRAKVECVRFSQGKP
EAAADAVRHLIIATQHLQHATVRLALVGGNPGTGKSTLARGVAELVGAQVISTDDVRRRL
RDCGVITGEPGVLDSGLYSRANVVAVYQEALRKARLLLGSGHSVILDGTWGDPQMRACAR
RLAADTHSAIVEFRCSATVDVMADRIVARAGGNSDATAEIAAALAARQADWDTGHRIDTA
GPRERSVGQAYHIWRSAI*

Genomic Sequence

>Rv2004c
ATGGACTCACCGACCAACGACGGCACGTGTGACGCCCATCCTGTGACAGATGAGCCTTTC
ATCGATGTGCGCGAAACCCACACCGCAGTGGTTGTGTTGGCCGGCGACCGGGCGTTCAAG
GCGAAAAAGCCTGTGGTGACGGATTTCTGCGACTTCCGCACGGCGGAACAGCGTGAGCGC
GCCTGTATCCGGGAATTCGAGTTGAATAGTCGGCTGGCCGCGCAGAGCTACTTGGGCATT
GCCCATCTCAGCGATCCAAGCGGCGGGCACGCCGAACCGGTCGTCGTCATGCGGCGTTAC
CGCGACAAGCAGCGGCTGGCGTCGATGGTGACCGCCGGCCTGCCGGTCGAGGGTGCCCTG
GACGCGATCGCTGAGGTGTTGGCCCGGTTTCACCAGCGCGCACAGCGTAACCGGTGCATC
GATACTCAAGGCGAGGTCGGTGCGGTGGCGCGGCGTTGGCACGAAAACCTGGCCGAACTT
CGCCACCACGCGGACAAAGTGGTCTCCGGGGATGTGATTCGGCGGATTGAACACATGGTC
GACGAATTCGTTTCCGGGCGCGAGGTTTTGTTCGCCGGCCGGATCAAAGAAGGTTGTATT
GTAGACGGCCACGCGGATCTACTGGCCGATGACATCTTCTTGGTGGATGGCGAACCGGCG
CTGCTGGATTGCTTGGAGTTCGAAGACGAGCTTCGCTACCTCGACCGCATCGACGACGCC
GCCTTTTTGGCCATGGATCTGGAGTTCTTGGGCCGCAAAGATCTTGGGGACTACTTCCTG
GCCGGCTATGCGGTGCGTTCGGGTGATACCGCCCCGGCGTCGCTGCGCGACTTCTACATT
GCTTATCGCGCGGTGGTGCGCGCGAAAGTCGAGTGCGTGCGATTCTCCCAGGGCAAACCG
GAGGCCGCTGCGGACGCCGTGCGCCACCTGATCATCGCCACCCAACACCTACAGCACGCT
ACGGTCCGGTTGGCGCTGGTCGGTGGCAATCCGGGCACCGGCAAGTCGACCCTGGCCCGC
GGGGTCGCCGAACTGGTGGGGGCGCAGGTGATCTCAACCGACGATGTGCGCCGGCGGCTA
CGCGATTGCGGAGTAATCACCGGGGAGCCCGGCGTTTTGGACTCCGGGCTCTACAGTCGT
GCCAACGTTGTGGCGGTCTACCAGGAGGCGCTGCGCAAAGCCCGCCTGCTCTTGGGTAGT
GGGCACTCAGTGATCCTCGACGGTACCTGGGGTGATCCGCAGATGCGCGCCTGCGCCCGG
CGTCTCGCGGCGGACACGCACTCGGCGATTGTCGAATTCAGGTGTTCGGCGACGGTTGAC
GTGATGGCCGACAGAATCGTTGCTAGAGCCGGGGGCAACTCCGACGCCACCGCCGAGATC
GCGGCGGCCTTGGCCGCCCGGCAAGCGGACTGGGACACCGGGCACCGGATCGACACGGCG
GGGCCGCGTGAGCGCTCCGTGGGACAGGCCTACCACATCTGGCGCAGCGCGATCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv0981	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. H. He, R. Hovey et al. MprAB is a stress-responsive two-component system that directly regulates expression of sigma factors SigB and SigE in Mycobacterium tuberculosis. J. Bacteriol. 2006
Interaction	RegulatedBy Rv3133c	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. HD. Park, KM. Guinn et al. Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis. Mol. Microbiol. 2003