Rv2077c - conserved membrane protein

Expression: Most Significant Conditions for Rv2077c

Protein Domains

Gene Information
Locus	Rv2077c
Symbol
Gene Name	conserved membrane protein
Location	2333323 - 2334294 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:972 bp Protein:324 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	12686
Related Genes	MAP2472 MAV_0500 MAV_0692 MAV_1450 MAV_1479 MAV_2254 MAV_3647 MSMEG_5460 MSMEG_5600 MT0644 MT1999 MT2000 MT2137 MUL_1130 MUL_1133 MUL_1136 Mvan_5711 Rv0614 Rv1949c Rv1950c
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2077c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2077c Transcript 1
MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRNQAHAIAWNGAGGDGLRQRTRA
DFSTVSGIADQLRRAATIARNGAGTIDAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQ
PAAVQAARLAQAQALAGDIRLRVGQLVAAENEVSGQLAATTGDVGNVRFAGAPVVAHSAV
QLVDFFKQDGPTPPPPGAPHPSGGADGPYSDPITSMMLPPAGTEAPVSDATKRWVDNMVN
ELAARPPDDPIAVEARRLAFQALHRPCNSAEWTAAVAGFAGSSAGVVGTALAIPAGPADW
ALLGAALLGVGGSGAAVVNCATK*

Genomic Sequence

>Rv2077c
ATGCTGGCCACCCTGTCCCAAATCCGGGCATGGAGCACCGAGCACCTTATCGATGCGGCC
GGCTACTGGACCGAAACCGCGGATCGGTGGGAAGACGTGTTTCTGCAGATGCGAAACCAG
GCCCATGCCATCGCCTGGAATGGCGCCGGGGGCGACGGGCTGCGACAACGAACCCGAGCT
GACTTCTCAACGGTCAGTGGCATAGCCGACCAGCTGCGGAGAGCAGCCACGATCGCGCGC
AACGGCGCCGGCACTATCGACGCGGCACAACGAAGAGTTATGTATGCTGTAGAGGACGCC
CAGGACGCCGGTTTCAACGTCGGTGAAGACCTATCGGTCACCGACACCAAAACGACGCAG
CCGGCTGCAGTGCAGGCCGCTCGACTAGCTCAGGCTCAGGCGTTGGCCGGTGACATCCGC
TTACGTGTCGGGCAACTGGTTGCGGCGGAGAACGAGGTGTCCGGTCAGCTCGCCGCGACC
ACCGGTGATGTGGGAAATGTCCGCTTCGCGGGCGCCCCGGTTGTTGCCCACAGCGCGGTT
CAGCTAGTCGACTTCTTCAAACAAGACGGCCCAACACCTCCACCGCCAGGAGCGCCACAC
CCGTCCGGTGGAGCCGACGGACCGTACTCCGATCCGATCACTTCAATGATGCTGCCACCG
GCCGGGACAGAGGCACCCGTATCAGACGCGACCAAACGGTGGGTGGACAACATGGTCAAC
GAGCTGGCCGCTAGGCCGCCGGATGACCCCATCGCGGTGGAGGCGCGCCGGCTGGCGTTT
CAAGCTCTGCACCGGCCATGTAACAGCGCGGAGTGGACGGCGGCTGTTGCGGGTTTCGCA
GGATCATCGGCTGGCGTAGTTGGGACCGCCCTAGCAATTCCGGCCGGCCCTGCCGACTGG
GCACTACTTGGCGCCGCCTTACTGGGGGTTGGCGGATCGGGAGCGGCGGTGGTCAACTGT
GCCACCAAGTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift M. Stapleton, I. Haq et al. Mycobacterium tuberculosis cAMP receptor protein (Rv3676) differs from the Escherichia coli paradigm in its cAMP binding and DNA binding properties and transcription activation properties. J. Biol. Chem. 2010
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	PhysicalInteraction Rv2431c	active	sourish10	2012-10-05
	Gene neighbourhood (Functional linkage) S. Tundup, N. Pathak et al. The co-operonic PE25/PPE41 protein complex of Mycobacterium tuberculosis elicits increased humoral and cell mediated immune response. PLoS ONE 2008
Interaction	PhysicalInteraction Rv2431c	active	ahal4789	2012-10-05
	Gene neighbourhood (Functional linkage) S. Tundup, N. Pathak et al. The co-operonic PE25/PPE41 protein complex of Mycobacterium tuberculosis elicits increased humoral and cell mediated immune response. PLoS ONE 2008
Interaction	RegulatedBy Rv3676	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008