Rv2158c - UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelat E ligase murE

Expression: Most Significant Conditions for Rv2158c

Protein Domains

Gene Information
Locus	Rv2158c
Symbol	murE
Gene Name	UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelat E ligase murE
Location	2419001 - 2420608 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1608 bp Protein:536 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	34299
Related Genes	Acel_1005 CE2058 cg2374 DIP1603 jk0745 MAP1902c MAV_2331 Mkms_3323 ML0909 Mmcs_3261 MSMEG_4232 MT2217 MUL_3506 Mvan_3528 nfa17610 PPA0753 SAV6117
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2158c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2158c Transcript 1
MSSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR
TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP
VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT
IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA
FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS
AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGV
SPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGA
GGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIAD
RRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA*

Genomic Sequence

>Rv2158c
GTGTCATCGCTGGCCCGAGGGATCTCGCGGCGGCGAACGGAGGTGGCGACACAGGTGGAG
GCTGCGCCCACTGGCTTGCGCCCCAACGCCGTCGTGGGCGTTCGGTTGGCCGCACTGGCC
GATCAGGTCGGCGCGGCCCTGGCCGAGGGTCCAGCTCAGCGTGCCGTCACCGAGGACCGG
ACGGTCACCGGGGTCACGCTGCGCGCCCAGGACGTGTCACCCGGTGACCTGTTCGCCGCC
CTGACCGGCTCGACCACCCACGGGGCCCGCCACGTCGGCGACGCGATCGCACGCGGCGCC
GTCGCGGTGCTCACCGACCCCGCCGGGGTCGCCGAGATCGCCGGACGAGCGGCCGTGCCC
GTGTTGGTGCACCCCGCACCCCGCGGCGTGCTCGGCGGCTTGGCCGCCACCGTGTACGGG
CATCCGTCCGAGCGGTTGACGGTTATCGGGATCACCGGAACGTCCGGCAAGACCACCACC
ACCTATCTGGTCGAGGCCGGGTTACGGGCTGCCGGACGCGTCGCCGGGCTGATCGGCACC
ATCGGCATCCGCGTCGGCGGCGCCGACCTTCCCAGCGCGCTGACCACCCCGGAGGCCCCC
ACGCTGCAGGCGATGCTGGCGGCGATGGTCGAACGCGGGGTGGACACCGTGGTCATGGAG
GTGTCCAGCCACGCGCTGGCGCTGGGCCGGGTGGACGGCACCCGGTTCGCCGTCGGCGCC
TTCACCAATCTCTCCCGTGACCACCTGGATTTCCACCCCAGCATGGCCGACTACTTCGAG
GCCAAGGCGTCATTGTTCGATCCGGACTCGGCACTGCGCGCCCGCACCGCCGTGGTGTGC
ATCGACGACGACGCCGGGCGCGCGATGGCGGCGCGGGCCGCCGACGCGATCACCGTCAGC
GCCGCCGACCGGCCCGCACACTGGCGCGCCACGGATGTGGCGCCCACGGACGCGGGCGGG
CAACAATTCACCGCCATCGACCCCGCCGGCGTAGGGCATCACATCGGAATCCGGCTACCG
GGCCGCTACAACGTCGCCAATTGCCTGGTCGCCCTGGCGATTCTGGACACCGTCGGGGTC
TCCCCGGAACAGGCGGTGCCGGGCCTGCGTGAGATCCGGGTCCCGGGGCGGCTCGAGCAG
ATCGACCGCGGCCAGGGCTTTCTCGCGCTGGTCGACTACGCGCACAAACCGGAAGCGCTG
CGGTCGGTGCTGACCACCTTGGCGCACCCGGACCGCCGGCTGGCGGTGGTGTTCGGCGCC
GGCGGCGATCGTGACCCGGGCAAGCGGGCCCCGATGGGCCGGATAGCCGCGCAGCTGGCC
GACTTGGTGGTCGTCACCGACGACAACCCGCGTGACGAAGATCCCACGGCGATCCGCCGC
GAAATCCTGGCTGGGGCGGCCGAAGTCGGCGGTGATGCCCAGGTCGTCGAGATCGCAGAC
CGGCGGGACGCGATCCGGCACGCGGTTGCCTGGGCGCGCCCCGGCGACGTGGTGCTCATC
GCCGGCAAAGGCCACGAGACCGGGCAACGCGGCGGCGGGCGGGTCCGCCCGTTCGACGAC
CGGGTGGAGCTGGCTGCCGCGCTAGAGGCCCTCGAGCGGCGCGCATGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Name	UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase	active	mjackson	2012-10-05
	Peptidoglycan precursor synthesis