Rv2178c - 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase aroG
Protein Domains

Gene Information
LocusRv2178c
SymbolaroG
Gene Name3-deoxy-D-arabino-heptulosonate 7-phosphate synthase aroG
Location2440332 - 2441720 (-)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:1389 bp
Protein:463 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number13895
Related GenesAcel_0984 CE2073 cg2391 DIP1616 jk0732 MAP1916c MAV_2317 Mkms_3335 ML0896 Mmcs_3273 MSMEG_4244 MT2234 MUL_3533 Mvan_3540 nfa17320 PPA0726 SAV6086
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
Search for regulators of Rv2178c
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionPhysicalInteraction Rv0948cactivegyanaranjan832012-10-05
Structural Analysis
M. Okvist, S. Sasso et al. A novel noncovalent complex of chorismate mutase and DAHP synthase from Mycobacterium tuberculosis: protein purification, crystallization and X-ray diffraction analysis. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2009
InteractionPhysicalInteraction Rv0948cactivegyanaranjan832012-10-05
Spectrophotometric Assay
M. Okvist, S. Sasso et al. A novel noncovalent complex of chorismate mutase and DAHP synthase from Mycobacterium tuberculosis: protein purification, crystallization and X-ray diffraction analysis. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2009
InteractionRegulatedBy Rv2710activeyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
JH. Lee, PC. Karakousis et al. Roles of SigB and SigF in the Mycobacterium tuberculosis sigma factor network. J. Bacteriol. 2008
InteractionRegulatedBy Rv0757activeyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
SB. Walters, E. Dubnau et al. The Mycobacterium tuberculosis PhoPR two-component system regulates genes essential for virulence and complex lipid biosynthesis. Mol. Microbiol. 2006
InteractionRegulatedBy Rv1395activeyamir.moreno2012-10-05
Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support.
G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008
InteractionRegulatedBy Rv3286cactiveyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
EP. Williams, JH. Lee et al. Mycobacterium tuberculosis SigF regulates genes encoding cell wall-associated proteins and directly regulates the transcriptional regulatory gene phoY1. J. Bacteriol. 2007
TermEC:2.5.1.54 3-deoxy-7-phosphoheptulonate synthase. - NRactivejjmcfadden2012-03-05
Inferred from direct assay
C. Rizzi, J. Frazzon et al. DAHP synthase from Mycobacterium tuberculosis H37Rv: cloning, expression, and purification of functional enzyme. Protein Expr. Purif. 2005