Rv2289 - cdp-diacylglycerol pyrophosphatase cdh

Expression: Most Significant Conditions for Rv2289

Protein Domains

Gene Information
Locus	Rv2289
Symbol	cdh
Gene Name	cdp-diacylglycerol pyrophosphatase cdh
Location	2561675 - 2562457 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:783 bp Protein:261 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	9090
Related Genes	ML1417 MT2346 MUL_2719 SAV524
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2289
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2289 Transcript 1
MPKSRRAVSLSVLIGAVIAALAGALIAVTVPARPNRPEADREALWKIVHDRCEFGYRRTG
AYAPCTFVDEQSGTALYKADFDPYQFLLIPLARITGIEDPALRESAGRNYLYDAWAARFL
VTARLNNSLPESDVVLTINPKNARTQDQLHIHISCSSPTTSAALRNVDTSEYVGWKQLPI
DLGGRRFQGLAVDTKAFESRNLFRDIYLKVTADGKKMENASIAVANVAQDQFLLLLAEGT
EDQPVAAETLQDHDCSITKS*

Genomic Sequence

>Rv2289
GTGCCCAAAAGCCGACGGGCAGTCAGTCTAAGTGTCTTGATAGGTGCGGTGATAGCAGCT
CTTGCCGGGGCGCTGATTGCGGTAACCGTACCGGCGCGGCCGAATCGCCCTGAGGCCGAC
CGTGAAGCACTGTGGAAAATCGTGCACGACCGTTGCGAATTCGGCTATCGGCGTACCGGT
GCGTACGCTCCCTGCACATTCGTGGATGAACAGTCTGGAACGGCGTTGTACAAAGCGGAT
TTTGATCCGTACCAGTTCCTTTTGATCCCGCTTGCTCGTATCACCGGAATCGAGGATCCC
GCCCTACGGGAGTCAGCGGGTCGCAATTACCTCTACGACGCTTGGGCCGCACGGTTCCTC
GTTACCGCGCGCCTGAACAACTCACTTCCAGAGTCAGACGTAGTCCTCACCATCAACCCG
AAGAACGCGCGCACTCAGGATCAGCTGCACATCCACATATCGTGTTCGTCACCAACAACA
TCGGCAGCCCTGAGGAACGTGGATACCTCAGAGTACGTTGGCTGGAAGCAGCTCCCCATC
GACCTCGGTGGTCGCAGGTTTCAAGGATTGGCGGTTGACACGAAGGCGTTCGAATCCAGG
AACCTGTTCCGGGACATCTACCTGAAGGTAACCGCTGACGGCAAGAAAATGGAAAATGCA
TCGATTGCGGTTGCCAACGTAGCGCAGGACCAATTCCTGCTGCTCTTGGCAGAGGGAACT
GAGGACCAGCCCGTTGCAGCCGAGACTCTCCAAGACCACGACTGCTCCATCACCAAGTCC
TGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Term	TBRXN:CDAPPA160 CDP-Diacylglycerol pyrophostatase (n-C16:0) - IPI	active	njamshidi	2012-10-05
	Phosphatidylinositol is required for mtb growth - see: 10889206 and 12657046 authors,CM. Sassetti,DH. Boyd,EJ. Rubin Genes required for mycobacterial growth defined by high density mutagenesis. Mol. Microbiol. 2003
Term	EC:3.6.1.26 CDP-diacylglycerol diphosphatase. - IPI	active	njamshidi	2012-10-05
	Phosphatidylinositol is required for mtb growth - see: 10889206 and 12657046 authors,CM. Sassetti,DH. Boyd,EJ. Rubin Genes required for mycobacterial growth defined by high density mutagenesis. Mol. Microbiol. 2003
Term	TBRXN:CDAPPA160 CDP-Diacylglycerol pyrophostatase (n-C16:0) - IPI	active	njamshidi	2012-10-05
	Phosphatidylinositol is required for mtb growth - see: 10889206 and 12657046 M. Jackson,DC. Crick,PJ. Brennan Phosphatidylinositol is an essential phospholipid of mycobacteria. J. Biol. Chem. 2000
Term	EC:3.6.1.26 CDP-diacylglycerol diphosphatase. - IPI	active	njamshidi	2012-10-05
	Phosphatidylinositol is required for mtb growth - see: 10889206 and 12657046 M. Jackson,DC. Crick,PJ. Brennan Phosphatidylinositol is an essential phospholipid of mycobacteria. J. Biol. Chem. 2000
Term	TBRXN:CDAPPA160 CDP-Diacylglycerol pyrophostatase (n-C16:0) - ISS	active	njamshidi	2012-10-05
	Phosphatidylinositol is required for mtb growth - see: 10889206 and 12657046 authors,CM. Sassetti,DH. Boyd,EJ. Rubin Genes required for mycobacterial growth defined by high density mutagenesis. Mol. Microbiol. 2003
Term	EC:3.6.1.26 CDP-diacylglycerol diphosphatase. - ISS	active	njamshidi	2012-10-05
	Phosphatidylinositol is required for mtb growth - see: 10889206 and 12657046 authors,CM. Sassetti,DH. Boyd,EJ. Rubin Genes required for mycobacterial growth defined by high density mutagenesis. Mol. Microbiol. 2003
Term	TBRXN:CDAPPA160 CDP-Diacylglycerol pyrophostatase (n-C16:0) - ISS	active	njamshidi	2012-10-05
	Phosphatidylinositol is required for mtb growth - see: 10889206 and 12657046 M. Jackson,DC. Crick,PJ. Brennan Phosphatidylinositol is an essential phospholipid of mycobacteria. J. Biol. Chem. 2000
Term	EC:3.6.1.26 CDP-diacylglycerol diphosphatase. - ISS	active	njamshidi	2012-10-05
	Phosphatidylinositol is required for mtb growth - see: 10889206 and 12657046 M. Jackson,DC. Crick,PJ. Brennan Phosphatidylinositol is an essential phospholipid of mycobacteria. J. Biol. Chem. 2000
Interaction	RegulatedBy Rv0757	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. SB. Walters, E. Dubnau et al. The Mycobacterium tuberculosis PhoPR two-component system regulates genes essential for virulence and complex lipid biosynthesis. Mol. Microbiol. 2006