Rv2509 - short-chain type dehydrogenase/reductase

Expression: Most Significant Conditions for Rv2509

Protein Domains

Gene Information
Locus	Rv2509
Symbol
Gene Name	short-chain type dehydrogenase/reductase
Location	2824678 - 2825484 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:807 bp Protein:269 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	37760
Related Genes	MAP2318 MAV_1666 Mkms_3711 ML0429 Mmcs_3638 MSMEG_4722 MT2584 MUL_3788 Mvan_4098 nfa12890
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2509
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2509 Transcript 1
MPIPAPSPDARAVVTGASQNIGAALATELAARGHHLIVTARREDVLTELAARLADKYRVT
VDVRPADLADPQERSKLADELAARPISILCANAGTATFGPIASLDLAGEKTQVQLNAVAV
HDLTLAVLPGMIERKAGGILISGSAAGNSPIPYNATYAATKAFVNTFSESLRGELRGSGV
HVTVLAPGPVRTELPDASEASLVEKLVPDFLWISTEHTARVSLNALERNKMRVVPGLTSK
AMSVASQYAPRAIVAPIVGAFYKRLGGS*

Genomic Sequence

>Rv2509
ATGCCGATACCCGCGCCCAGCCCCGACGCACGTGCCGTTGTCACCGGGGCTTCGCAGAAC
ATCGGCGCGGCGCTGGCCACCGAACTGGCCGCACGCGGGCACCACCTGATCGTCACCGCA
CGACGCGAGGACGTGTTGACCGAGTTGGCTGCCCGGCTGGCCGACAAGTACCGCGTCACG
GTCGACGTGCGACCGGCCGATCTGGCCGATCCGCAAGAACGATCGAAACTGGCCGACGAG
CTGGCTGCCCGGCCCATCTCGATCCTGTGCGCCAACGCGGGTACCGCGACATTCGGCCCG
ATCGCATCGCTCGATCTTGCCGGCGAAAAGACGCAGGTGCAGTTGAATGCCGTGGCGGTG
CACGACCTTACGTTGGCGGTGTTGCCGGGCATGATCGAGCGCAAGGCCGGCGGCATCTTG
ATTTCTGGTTCGGCGGCCGGCAATTCACCGATTCCCTACAACGCCACCTATGCCGCGACC
AAGGCCTTCGTGAACACCTTCAGCGAATCTCTGCGCGGTGAGCTACGCGGCTCCGGCGTG
CACGTCACGGTGCTGGCCCCGGGCCCGGTTCGCACCGAGCTACCGGATGCCTCCGAAGCG
TCACTGGTCGAGAAGCTGGTGCCGGACTTCCTGTGGATCTCGACGGAGCACACCGCCCGG
GTATCGCTGAATGCCTTGGAGCGCAACAAGATGCGCGTCGTTCCGGGTCTGACGTCAAAG
GCGATGTCGGTGGCCAGCCAATACGCTCCGCGCGCCATCGTGGCGCCAATCGTGGGTGCC
TTTTACAAGAGGCTTGGGGGCAGCTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Name	SHORT-CHAIN TYPE REDUCTASE, reducing 2-alkyl-3-keto mycolate	active	mjackson	2012-10-05
	Claisen-type condensation
Symbol	cmrA	active	mjackson	2012-10-05
	Claisen-type condensation
Term	EC:1.-.-.- Oxidoreductases. - NR	active	extern:JZUCKER	2012-03-06
	Inferred by a human based on computational evidence A. Bhatt, AK. Brown et al. Loss of a mycobacterial gene encoding a reductase leads to an altered cell wall containing beta-oxo-mycolic acid analogs and accumulation of ketones. Chem. Biol. 2008