Rv2591 - PE-PGRS family protein


Protein Domains

Gene Information
LocusRv2591
SymbolPE_PGRS44
Gene NamePE-PGRS family protein
Location2921551 - 2923182 (+)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:1632 bp
Protein:544 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number37132
Related GenesCE1765 cg1857 DIP1363 jk1047 MUL_1721
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
Search for regulators of Rv2591
Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionTranscription Rv3676activejgalag2012-10-05
Band shift
M. Stapleton, I. Haq et al. Mycobacterium tuberculosis cAMP receptor protein (Rv3676) differs from the Escherichia coli paradigm in its cAMP binding and DNA binding properties and transcription activation properties. J. Biol. Chem. 2010
InteractionTranscription Rv3676activejgalag2012-10-05
Band shift
G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
InteractionTranscription Rv3676activexaccheus2012-10-05

authors,Y. Akhter,S. Yellaboina,A. Farhana,A. Ranjan,N. Ahmed,SE. Hasnain Genome scale portrait of cAMP-receptor protein (CRP) regulons in mycobacteria points to their role in pathogenesis. Gene 2008
InteractionRegulatedBy Rv2710activeyamir.moreno2012-10-05
Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments..
JH. Lee, PC. Karakousis et al. Roles of SigB and SigF in the Mycobacterium tuberculosis sigma factor network. J. Bacteriol. 2008
InteractionRegulatedBy Rv3676activeyamir.moreno2012-10-05
Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support.
G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008