Rv2869c - conserved membrane protein

Expression: Most Significant Conditions for Rv2869c

Protein Domains

Gene Information
Locus	Rv2869c
Symbol
Gene Name	conserved membrane protein
Location	3180548 - 3181762 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1215 bp Protein:405 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	768
Related Genes	Acel_1523 CE1904 cg2207 DIP1499 jk1166 MAP2939c MAV_3726 Mkms_2089 ML1582 Mmcs_2043 MSMEG_2579 MT2937 MUL_2086 Mvan_2261 nfa41190 PPA1509 SAV2562
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2869c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2869c Transcript 1
MMFVTGIVLFALAILISVALHECGHMWVARRTGMKVRRYFVGFGPTLWSTRRGETEYGVK
AVPLGGFCDIAGMTPVEELDPDERDRAMYKQATWKRVAVLFAGPGMNLAICLVLIYAIAL
VWGLPNLHPPTRAVIGETGCVAQEVSQGKLEQCTGPGPAALAGIRSGDVVVKVGDTPVSS
FDEMAAAVRKSHGSVPIVVERDGTAIVTYVDIESTQRWIPNGQGGELQPATVGAIGVGAA
RVGPVRYGVFSAMPATFAVTGDLTVEVGKALAALPTKVGALVRAIGGGQRDPQTPISVVG
ASIIGGDTVDHGLWVAFWFFLAQLNLILAAINLLPLLPFDGGHIAVAVFERIRNMVRSAR
GKVAAAPVNYLKLLPATYVVLVLVVGYMLLTVTADLVNPIRLFQ*

Genomic Sequence

>Rv2869c
ATGATGTTTGTTACCGGCATTGTGCTGTTCGCGCTCGCGATCCTGATTTCGGTGGCCCTG
CACGAATGTGGTCACATGTGGGTCGCGCGCCGCACCGGGATGAAGGTACGTCGCTATTTC
GTCGGCTTTGGCCCCACGTTGTGGTCGACCCGGCGCGGCGAGACCGAATACGGTGTCAAA
GCCGTTCCGCTGGGCGGCTTCTGTGACATCGCCGGCATGACCCCGGTCGAGGAACTCGAC
CCCGACGAACGTGACCGTGCGATGTACAAGCAGGCCACCTGGAAGCGGGTCGCAGTGTTA
TTCGCCGGGCCCGGAATGAACCTCGCTATCTGCCTGGTGCTGATCTATGCCATCGCGCTG
GTCTGGGGGCTGCCTAACCTGCATCCGCCAACCAGGGCCGTAATCGGCGAAACTGGCTGC
GTTGCACAGGAAGTGAGCCAGGGCAAGCTCGAGCAGTGCACCGGGCCCGGTCCGGCGGCG
CTGGCCGGAATTCGCTCCGGTGACGTCGTGGTCAAGGTCGGTGACACCCCGGTGTCCAGT
TTCGACGAGATGGCCGCCGCGGTGCGCAAGTCACACGGCAGCGTCCCGATCGTTGTCGAG
CGTGACGGCACCGCGATTGTTACCTACGTGGACATCGAATCCACCCAACGCTGGATCCCT
AACGGGCAGGGCGGTGAGCTCCAGCCGGCAACGGTCGGTGCGATTGGGGTGGGCGCCGCC
CGGGTCGGGCCTGTGCGCTACGGCGTGTTCTCCGCCATGCCGGCCACATTCGCGGTCACC
GGCGACCTGACCGTGGAGGTGGGCAAGGCGCTGGCCGCCCTCCCGACCAAGGTAGGTGCG
CTGGTGCGGGCGATCGGCGGCGGGCAGCGTGACCCGCAGACGCCGATAAGTGTGGTGGGC
GCCAGCATCATCGGCGGCGACACCGTCGACCATGGGCTGTGGGTGGCGTTCTGGTTCTTC
TTGGCCCAGCTGAACCTCATCCTGGCTGCGATCAACCTGCTGCCGTTGCTGCCGTTCGAT
GGCGGCCATATTGCCGTCGCGGTGTTCGAGAGGATCCGCAACATGGTCCGGTCGGCTCGT
GGCAAGGTGGCGGCCGCACCGGTGAATTACCTCAAACTCTTGCCGGCGACCTATGTGGTC
TTGGTTCTTGTCGTCGGGTACATGCTCTTGACCGTCACCGCCGACCTGGTCAACCCGATT
AGGCTTTTCCAGTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Inhibition Rv3912	active	sourish10	2012-10-05
	Affinity purification (Physical interaction) authors,JG. Sklar,H. Makinoshima,JS. Schneider,MS. Glickman M. tuberculosis intramembrane protease Rip1 controls transcription through three anti-sigma factor substrates. Mol. Microbiol. 2010
Interaction	Regulatory Rv1124	active	ashwinigbhat	2012-10-05
	Microarrary Analysis H. Makinoshima & MS. Glickman Regulation of Mycobacterium tuberculosis cell envelope composition and virulence by intramembrane proteolysis. Nature 2005