Rv2913c - D-amino acid aminohydrolase

Expression: Most Significant Conditions for Rv2913c

Protein Domains

Gene Information
Locus	Rv2913c
Symbol
Gene Name	D-amino acid aminohydrolase
Location	3219863 - 3221698 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1836 bp Protein:612 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	19681
Related Genes	MAP2981c MAV_3768 MSMEG_6141 MT2981 MUL_2043
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv2913c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv2913c Transcript 1
MLAWRQLNDLEETVTYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVAAGALDETGCPE
VVDAAGKWVVPGFIDVHTHYDAEVLLDPGLRESVRHGVTTVLLGNCSLSTVYANSEDAAD
LFSRVEAVPREFVLGALRDNQTWSTPAEYIEAIDALPLGPNVSSLLGHSDLRTAVLGLDR
ATDDTVRPTEAELAKMAKLLDEALEAGMLGMSGMDAAIDKLDGDRFRSRALPSTFATWRE
RRKLISVLRHRGRILQSAPDVDNPVSALLFFLASSRIFNRRKGVRMSMLVSADAKSMPLA
VHVFGLGTRVLNKLLGSQVRFQHLPVPFELYSDGIDLPVFEEFGAGTAALHLRDQLQRNE
LLADRSYRRSFRREFDRIKLGPSLWHRDFHDAVIVECPDKSLIGKSFGAIADERGLHPLD
AFLDVLVDNGERNVRWTTIVANHRPNQLNKLAAEPSVHMGFSDAGAHLRNMAFYNFGLRL
LKRARDADRAGQPFLSIERAVYRLTGELAEWFGIGAGTLRQGDRADFAVIDPTHLDESVD
GYHEEAVPYYGGLRRMVNRNDATVVATGVGGTVVFRGGQFGGQFRDGYGQNVKSGRYLRA
GELGAALSRSA*

Genomic Sequence

>Rv2913c
ATGTTAGCTTGGCGGCAACTCAACGATCTGGAGGAAACGGTGACCTACGACGTGATCATT
CGCGACGGACTGTGGTTCGACGGCACCGGCAATGCGCCATTGACTCGCACTCTGGGCATT
CGCGACGGCGTGGTGGCCACGGTGGCTGCCGGCGCACTGGACGAGACCGGCTGCCCGGAG
GTGGTTGATGCGGCGGGGAAGTGGGTCGTGCCTGGCTTCATCGACGTGCACACCCACTAT
GACGCCGAGGTGTTGCTCGATCCTGGTTTGCGGGAGTCGGTGCGCCACGGTGTCACCACG
GTGCTGCTGGGAAACTGCTCGTTGTCGACGGTCTACGCCAACTCCGAGGATGCCGCCGAC
CTGTTCAGCCGTGTTGAAGCGGTGCCCCGCGAATTTGTCCTGGGTGCCCTGCGGGACAAC
CAGACGTGGTCGACGCCCGCGGAGTACATCGAAGCGATCGACGCCCTGCCCCTCGGGCCG
AATGTGAGTTCACTGCTTGGCCATTCGGATCTGCGGACCGCGGTACTGGGCCTTGATCGT
GCCACCGACGACACCGTCCGGCCCACCGAAGCCGAGCTGGCGAAGATGGCGAAACTGCTC
GATGAGGCGCTCGAGGCCGGGATGCTGGGCATGTCCGGGATGGACGCCGCTATCGACAAG
CTCGACGGCGACCGCTTCCGCTCGCGTGCGCTGCCGTCCACCTTCGCGACCTGGCGGGAG
CGTCGCAAGCTGATCTCGGTGCTGCGCCACCGGGGCCGGATACTGCAGAGCGCACCCGAC
GTCGACAACCCGGTGTCCGCGCTGCTGTTTTTCTTGGCCAGCAGCCGGATATTCAACCGG
CGCAAGGGCGTTCGAATGAGCATGTTGGTGTCCGCCGACGCCAAGTCGATGCCGCTGGCG
GTACACGTGTTCGGGTTGGGCACCCGCGTGCTGAACAAGCTCTTAGGCTCTCAGGTGCGA
TTCCAGCATCTGCCGGTCCCGTTCGAGCTGTACTCCGACGGCATCGACCTGCCGGTCTTC
GAGGAGTTCGGCGCCGGAACGGCGGCCCTTCATCTGCGTGACCAACTGCAGCGCAACGAG
CTCCTGGCCGACAGGTCTTACCGCCGGTCGTTCCGGCGCGAGTTCGATCGCATCAAGCTC
GGACCTTCGTTGTGGCATCGGGACTTCCACGACGCCGTGATCGTCGAATGCCCGGATAAG
TCGTTGATCGGTAAGAGTTTCGGGGCAATAGCCGACGAGCGCGGGCTGCACCCGCTGGAC
GCGTTCCTCGATGTGCTGGTGGACAACGGGGAGCGCAATGTCCGATGGACCACCATCGTC
GCCAATCACCGGCCCAACCAGCTGAACAAGCTGGCCGCCGAACCGAGTGTCCACATGGGC
TTCTCCGACGCCGGCGCGCACCTGCGCAATATGGCGTTCTACAACTTCGGGCTTCGGCTG
CTCAAACGAGCCAGAGACGCCGACCGGGCCGGACAACCGTTTCTGTCCATCGAGCGGGCA
GTGTATCGCCTCACCGGTGAGTTGGCCGAGTGGTTCGGTATAGGCGCGGGCACGTTGCGC
CAGGGTGACCGTGCGGACTTCGCGGTGATTGACCCTACCCACCTAGATGAATCGGTGGAC
GGGTACCACGAGGAGGCGGTGCCCTACTATGGCGGTCTGCGACGCATGGTCAACCGCAAC
GATGCGACCGTGGTTGCGACGGGCGTGGGCGGCACCGTGGTATTCCGCGGAGGCCAGTTC
GGAGGTCAGTTCCGCGACGGCTACGGGCAGAACGTGAAGTCGGGTCGCTACCTGCGGGCG
GGTGAGCTCGGCGCCGCTCTGAGCCGTTCTGCCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Signaling Rv2914c	active	priti.priety	2012-10-05
	Affinity purification (Physical interaction) A. Singh, Y. Singh et al. Protein kinase I of Mycobacterium tuberculosis: cellular localization and expression during infection of macrophage-like cells. Tuberculosis (Edinburgh, Scotland) 2006
Interaction	Signaling Rv2914c	active	priti.priety	2012-10-05
	Affinity purification (Physical interaction) R. Gopalaswamy, S. Narayanan et al. The serine/threonine protein kinase PknI controls the growth of Mycobacterium tuberculosis upon infection. FEMS Microbiol. Lett. 2009
Interaction	Signaling Rv2914c	active	priti.priety	2012-10-05
	Affinity purification (Physical interaction) R. Gopalaswamy, PR. Narayanan et al. Cloning, overexpression, and characterization of a serine/threonine protein kinase pknI from Mycobacterium tuberculosis H37Rv. Protein Expr. Purif. 2004
Interaction	Operon Rv2916c	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) R. Gopalaswamy, S. Narayanan et al. The serine/threonine protein kinase PknI controls the growth of Mycobacterium tuberculosis upon infection. FEMS Microbiol. Lett. 2009
Interaction	Operon Rv2914c	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) R. Gopalaswamy, S. Narayanan et al. The serine/threonine protein kinase PknI controls the growth of Mycobacterium tuberculosis upon infection. FEMS Microbiol. Lett. 2009
Interaction	Operon Rv2916c	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) Y. Av-Gay,M. Everett The eukaryotic-like Ser/Thr protein kinases of Mycobacterium tuberculosis. Trends Microbiol. 2000
Interaction	Operon Rv2914c	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) Y. Av-Gay,M. Everett The eukaryotic-like Ser/Thr protein kinases of Mycobacterium tuberculosis. Trends Microbiol. 2000
Interaction	Operon Rv2916c	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) authors,A. Zelikovski,J. Abu-Dalu,I. Urca Meso-appendicular testis. Br J Urol 1975
Interaction	Operon Rv2914c	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) authors,A. Zelikovski,J. Abu-Dalu,I. Urca Meso-appendicular testis. Br J Urol 1975
Interaction	Operon Rv2916c	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) authors,BM. Altura Role of prostaglandins and histamine in reactive hyperemia: in-vivo studies on single mesenteric arterioles. Prostaglandins Med 1978
Interaction	Operon Rv2914c	active	ashwinigbhat	2012-10-05
	Co-expression (Functional linkage) authors,BM. Altura Role of prostaglandins and histamine in reactive hyperemia: in-vivo studies on single mesenteric arterioles. Prostaglandins Med 1978