Rv2951c - oxidoreductase
Protein Domains

Gene Information
LocusRv2951c
Symbol
Gene Nameoxidoreductase
Location3303103 - 3304248 (-)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:1146 bp
Protein:382 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number22458
Related GenesMAP0059c MAV_0066 ML0131 MT3025
Transcriptional Regulation
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Regulatory Network
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Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
NameKetoreductase catalyzing the reduction of (phenol)phthiodiolone to yield (phenol)phthiotriol in the biosynthesis of phthiocerol dimycocerosates and phenolic glycolipidsactivemjackson2012-10-05
Phthiocerol dimycocerosates (PDIM), phenolic glycolipids (PGL) and para-hydroxybenzoic acid derivatives
OtherTBPWY:Phthiocerol dimycocerosates, PGL & pHBADactivemjackson2012-03-05
Ketoreductase catalyzing the reduction of (phenol)phthiodiolone to yield (phenol)phthiotriol in the biosynthesis of phthiocerol dimycocerosates and phenolic glycolipids (phenotypic [mycobacterial recombinant strains])
R. Siméone, P. Constant et al. Molecular dissection of the biosynthetic relationship between phthiocerol and phthiodiolone dimycocerosates and their critical role in the virulence and permeability of Mycobacterium tuberculosis. FEBS J. 2007
OtherTBPWY:Phthiocerol dimycocerosates, PGL & pHBADactivemjackson2012-03-05
Ketoreductase catalyzing the reduction of (phenol)phthiodiolone to yield (phenol)phthiotriol in the biosynthesis of phthiocerol dimycocerosates and phenolic glycolipids (phenotypic [mycobacterial recombinant strains])
authors,KC. Onwueme,CJ. Vos,J. Zurita,CE. Soll,LE. Quadri Identification of phthiodiolone ketoreductase, an enzyme required for production of mycobacterial diacyl phthiocerol virulence factors. J. Bacteriol. 2005
TermEC:1.-.-.- Oxidoreductases. - NRactivejjmcfadden2012-03-05
Inferred from direct assay
P. Constant, E. Perez et al. Role of the pks15/1 gene in the biosynthesis of phenolglycolipids in the Mycobacterium tuberculosis complex. Evidence that all strains synthesize glycosylated p-hydroxybenzoic methyl esters and that strains devoid of phenolglycolipids harbor a frameshift mutation in the pks15/1 gene. J. Biol. Chem. 2002