Rv3085 - short-chain type dehydrogenase/reductase

Expression: Most Significant Conditions for Rv3085

Protein Domains

Gene Information
Locus	Rv3085
Symbol
Gene Name	short-chain type dehydrogenase/reductase
Location	3450920 - 3451750 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:831 bp Protein:277 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	22630
Related Genes	MT3170
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3085
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3085 Transcript 1
MSSFEGKVAVITGAGSGIGRALALNLSEKRAKLALSDVDTDGLAKTVRLAQALGAQVKSD
RLDVAEREAVLAHADAVVAHFGTVHQVYNNAGIAYNGNVDKSEFKDIERIIDVDFWGVVN
GTKAFLPHVIASGDGHIVNISSLFGLIAVPGQSAYNAAKFAVRGFTEALRQEMLVARHPV
KVTCVHPGGIKTAVARNATVADGEDQQTFAEFFDRRLALHSPEMAAKTIVNGVAKGQARV
VVGLEAKAVDVLARIMGSSYQRLVAAGVAKFFPWAK*

Genomic Sequence

>Rv3085
ATGAGCTCATTCGAAGGCAAGGTCGCCGTCATCACCGGGGCCGGCTCGGGCATCGGCAGA
GCGTTGGCACTCAACCTCTCCGAGAAGCGCGCAAAGCTTGCCCTTTCCGATGTCGACACC
GACGGGCTGGCCAAAACCGTGCGCCTGGCTCAAGCGCTCGGCGCGCAGGTGAAGTCGGAC
CGGCTCGACGTCGCCGAACGCGAGGCGGTGCTGGCCCACGCCGACGCCGTCGTCGCACAT
TTCGGCACCGTGCACCAGGTCTACAACAACGCCGGCATCGCGTACAACGGCAACGTCGAC
AAGTCGGAGTTCAAGGACATCGAGCGCATCATCGACGTCGACTTCTGGGGCGTCGTCAAC
GGCACCAAAGCCTTTCTGCCGCACGTGATTGCCTCCGGCGACGGACACATCGTCAACATC
TCCAGCCTGTTCGGGCTGATCGCGGTGCCCGGGCAAAGCGCCTACAACGCGGCCAAGTTC
GCGGTGCGCGGCTTCACCGAGGCGCTGCGCCAGGAGATGCTGGTCGCCAGGCATCCGGTC
AAGGTGACGTGCGTGCATCCCGGCGGCATCAAAACCGCCGTCGCGCGCAACGCCACCGTG
GCCGACGGCGAGGACCAGCAGACGTTCGCGGAGTTCTTCGACCGCCGGCTGGCGCTGCAT
TCGCCGGAGATGGCCGCCAAAACCATCGTCAACGGAGTCGCCAAGGGCCAGGCCCGCGTC
GTGGTCGGCCTGGAGGCCAAAGCCGTCGATGTGCTCGCGCGCATCATGGGCTCGTCGTAT
CAGCGGCTGGTTGCCGCCGGCGTCGCCAAGTTCTTCCCCTGGGCCAAGTAG

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Transcription Rv3088	active	sourish10	2012-10-05
	Operon (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Activation Rv3080c	active	sourish10	2012-10-05
	Structural Analysis P. Kumar, D. Kumar et al. The Mycobacterium tuberculosis protein kinase K modulates activation of transcription from the promoter of mycobacterial monooxygenase operon through phosphorylation of the transcriptional regulator VirS. J. Biol. Chem. 2009
Interaction	Activation Rv3080c	active	sourish10	2012-10-05
	Spectrophotometric P. Kumar, D. Kumar et al. The Mycobacterium tuberculosis protein kinase K modulates activation of transcription from the promoter of mycobacterial monooxygenase operon through phosphorylation of the transcriptional regulator VirS. J. Biol. Chem. 2009
Interaction	Transcription Rv3082c	active	sourish10	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3089	active	sourish10	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3088	active	sourish10	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3087	active	sourish10	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3086	active	sourish10	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3084	active	sourish10	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3083	active	sourish10	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3084	active	sourish10	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3083	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3082c	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	Transcription Rv3082c	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) P. Kumar, D. Kumar et al. The Mycobacterium tuberculosis protein kinase K modulates activation of transcription from the promoter of mycobacterial monooxygenase operon through phosphorylation of the transcriptional regulator VirS. J. Biol. Chem. 2009
Interaction	Transcription Rv3082c	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) A. Singh, R. Gupta et al. Requirement of the mymA operon for appropriate cell wall ultrastructure and persistence of Mycobacterium tuberculosis in the spleens of guinea pigs. J. Bacteriol. 2005
Interaction	Activation Rv3080c	active	priyadarshinipriyanka2001	2012-10-05
	Affinity purification (Physical interaction) P. Kumar, D. Kumar et al. The Mycobacterium tuberculosis protein kinase K modulates activation of transcription from the promoter of mycobacterial monooxygenase operon through phosphorylation of the transcriptional regulator VirS. J. Biol. Chem. 2009
Interaction	RegulatedBy Rv3082c	active	yamir.moreno	2012-10-05
	LacZ-promoter fusion. expression levels of LacZ- regulated promoter fusion measured and compared between wild-type and trans-element mutation (knockout, over expression etc.). Gfp-promoter fusion. expression levels of gfp-regulated promoter fusion measured and compared between wild-type and trans-element mutation (knockout, over expression etc.). A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003
Interaction	RegulatedBy Rv3082c	active	yamir.moreno	2012-10-05
	LacZ-promoter fusion. expression levels of LacZ- regulated promoter fusion measured and compared between wild-type and trans-element mutation (knockout, over expression etc.). Gfp-promoter fusion. expression levels of gfp-regulated promoter fusion measured and compared between wild-type and trans-element mutation (knockout, over expression etc.). A. Singh, S. Jain et al. mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope. FEMS Microbiol. Lett. 2003