Rv3454 - conserved membrane protein

Expression: Most Significant Conditions for Rv3454

Protein Domains

Gene Information
Locus	Rv3454
Symbol
Gene Name	conserved membrane protein
Location	3874822 - 3876090 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1269 bp Protein:423 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	9257
Related Genes
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3454
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3454 Transcript 1
MAQGLKLGLHIPLWAGYACSTLIIFPLVVYGMKVLSQLQLWTTPLWLILMAAPFGYLVVS
HPDSIGQFFSYAGKDGHGGLSFGSVLLAAGVCLSLIAQIAEQIDYLRFMPPRTPENANRW
WTWTLLAGPGWVAFGATKQIIGLFLAVYLMANIPGSSTIANQPVHQFMQIYRTFVPGWLA
LTLAVILVVLSQIKINVTNAYSGSLAWTNSFTRLTKHYPGRVVFLGVNLAIALILMEANM
FDFLNTILGCYANCGMAWVVAVASDIGFNKYLLGLSPKTPEFRRGMLYAINPVGFGSLLL
AAGLSIVTFFGGLGAALQPYSPLVAIVTALVMPPILAAATKGKYYLRRTHDGIDLPMYDE
HGNPSAAVLTCHVCHQDFERPDMLACQTHGAHVCSLCLSTDKQAEHVLPGLARAHIPGDQ
VP*

Genomic Sequence

>Rv3454
ATGGCTCAGGGCCTTAAGCTAGGCCTGCACATTCCGCTGTGGGCGGGTTACGCGTGCTCG
ACCCTGATCATCTTCCCGCTGGTGGTCTACGGGATGAAAGTTTTGTCACAGCTGCAACTT
TGGACCACCCCGCTCTGGCTGATCCTGATGGCGGCCCCATTTGGCTACCTGGTAGTCAGC
CATCCCGATTCGATTGGACAGTTTTTCTCCTACGCCGGCAAGGATGGTCATGGCGGCCTT
AGCTTCGGTTCTGTCCTGTTGGCAGCGGGAGTGTGCCTGTCACTCATCGCTCAGATCGCC
GAGCAGATCGACTACCTGCGCTTCATGCCGCCACGGACGCCGGAGAACGCGAACAGGTGG
TGGACGTGGACGCTGCTGGCCGGTCCCGGCTGGGTTGCATTTGGGGCGACCAAACAGATC
ATCGGCCTGTTCCTGGCGGTCTATCTGATGGCCAACATCCCCGGCTCGTCGACAATCGCC
AACCAGCCGGTGCACCAATTCATGCAGATATACCGCACCTTCGTACCGGGCTGGCTGGCG
TTGACACTCGCCGTCATCCTGGTGGTCTTGAGCCAGATCAAGATCAACGTCACGAACGCG
TATTCGGGCTCGCTGGCGTGGACCAATTCATTCACACGGCTCACCAAGCACTATCCCGGG
CGGGTCGTGTTTCTTGGGGTTAACCTCGCGATTGCGTTGATTCTCATGGAAGCCAACATG
TTTGACTTCCTGAACACAATCCTGGGTTGCTACGCCAATTGCGGTATGGCCTGGGTGGTG
GCGGTGGCGTCGGACATCGGCTTCAACAAGTATCTGCTCGGCCTGTCGCCGAAGACTCCC
GAATTCCGCCGCGGCATGCTATACGCCATCAACCCGGTCGGCTTCGGGTCGTTGCTGCTG
GCCGCGGGGCTGTCGATCGTCACCTTCTTCGGCGGTCTGGGTGCGGCACTGCAGCCTTAT
TCACCATTGGTGGCAATCGTCACCGCGTTGGTAATGCCGCCCATTCTGGCAGCCGCGACC
AAAGGCAAGTACTACCTTCGCCGCACGCACGACGGTATCGATCTGCCCATGTACGACGAG
CACGGCAATCCCTCGGCCGCGGTGTTGACTTGCCATGTCTGCCACCAGGATTTCGAGCGG
CCCGACATGCTGGCCTGCCAGACCCATGGTGCGCATGTCTGTTCGCTGTGCTTGTCCACG
GACAAGCAGGCCGAGCATGTGCTTCCTGGGTTAGCCCGAGCGCACATCCCGGGTGACCAA
GTTCCGTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift M. Stapleton, I. Haq et al. Mycobacterium tuberculosis cAMP receptor protein (Rv3676) differs from the Escherichia coli paradigm in its cAMP binding and DNA binding properties and transcription activation properties. J. Biol. Chem. 2010
Interaction	Transcription Rv3676	active	jgalag	2012-10-05
	Band shift G. Bai, LA. McCue et al. Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein. J. Bacteriol. 2005
Interaction	RegulatedBy Rv3676	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008