Rv3490 - alpha, alpha-trehalose-phosphate synthase otsA

Expression: Most Significant Conditions for Rv3490

Protein Domains

Gene Information
Locus	Rv3490
Symbol	otsA
Gene Name	alpha, alpha-trehalose-phosphate synthase otsA
Location	3908236 - 3909738 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1503 bp Protein:501 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	13902
Related Genes	Acel_1953 CE2508 cg2907 DIP1966 jk0332 MAP0573c MAV_0666 Mkms_4697 ML2254 Mmcs_4609 MSMEG_5892 MT3594 MUL_4052 Mvan_5192 nfa5470 PPA0961 SAV3936
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3490
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3490 Transcript 1
MAPSGGQEAQICDSETFGDSDFVVVANRLPVDLERLPDGSTTWKRSPGGLVTALEPVLRR
RRGAWVGWPGVNDDGAEPDLHVLDGPIIQDELELHPVRLSTTDIAQYYEGFSNATLWPLY
HDVIVKPLYHREWWDRYVDVNQRFAEAASRAAAHGATVWVQDYQLQLVPKMLRMLRPDLT
IGFFLHIPFPPVELFMQMPWRTEIIQGLLGADLVGFHLPGGAQNFLILSRRLVGTDTSRG
TVGVRSRFGAAVLGSRTIRVGAFPISVDSGALDHAARDRNIRRRAREIRTELGNPRKILL
GVDRLDYTKGIDVRLKAFSELLAEGRVKRDDTVVVQLATPSRERVESYQTLRNDIERQVG
HINGEYGEVGHPVVHYLHRPAPRDELIAFFVASDVMLVTPLRDGMNLVAKEYVACRSDLG
GALVLSEFTGAAAELRHAYLVNPHDLEGVKDGIEEALNQTEEAGRRRMRSLRRQVLAHDV
DRWAQSFLDALAGAHPRGQG*

Genomic Sequence

>Rv3490
ATGGCTCCCTCGGGAGGCCAGGAGGCGCAGATTTGCGATTCGGAGACCTTCGGGGACTCT
GACTTCGTGGTGGTAGCCAATCGACTGCCCGTCGATCTGGAGCGTCTTCCCGACGGCAGC
ACAACCTGGAAACGCAGCCCCGGAGGCTTGGTCACCGCCTTGGAGCCGGTGCTGCGGCGT
CGGCGCGGGGCCTGGGTCGGCTGGCCCGGCGTTAACGACGACGGGGCCGAACCCGACCTC
CACGTGCTGGACGGCCCCATCATCCAAGACGAGCTGGAACTTCATCCGGTACGGCTGAGC
ACCACGGACATAGCTCAGTACTACGAGGGATTCTCCAACGCCACACTGTGGCCGCTGTAC
CACGACGTCATCGTCAAGCCGCTCTACCACCGCGAATGGTGGGATCGCTACGTCGACGTC
AACCAGCGCTTTGCCGAGGCCGCGTCGCGCGCCGCCGCCCACGGCGCAACCGTGTGGGTA
CAGGACTACCAGCTGCAGCTGGTACCGAAGATGCTGCGCATGCTGCGGCCCGATCTGACC
ATCGGTTTCTTTTTGCACATCCCGTTCCCGCCGGTAGAGCTGTTTATGCAGATGCCGTGG
CGCACCGAGATCATCCAGGGCCTACTGGGCGCCGACCTGGTGGGCTTCCATCTTCCGGGC
GGTGCCCAGAATTTCCTGATCCTGTCCCGGCGTCTGGTCGGCACCGACACTTCCCGCGGA
ACCGTCGGTGTGCGGTCGCGGTTCGGTGCGGCGGTGCTCGGGTCCCGCACCATACGAGTT
GGCGCCTTTCCTATCTCGGTTGACTCCGGCGCGCTCGACCACGCTGCCCGCGACCGCAAC
ATCAGGCGCCGGGCCCGCGAGATTCGCACCGAACTGGGAAATCCGCGCAAGATCCTGCTC
GGTGTTGACCGGCTCGACTACACCAAGGGCATCGACGTACGGCTGAAGGCCTTTTCCGAG
CTGCTGGCCGAGGGCCGCGTCAAACGCGACGACACCGTCGTGGTCCAGCTGGCTACCCCG
AGCCGCGAGCGGGTGGAGAGCTACCAGACGCTGCGCAACGACATCGAACGCCAGGTCGGC
CACATTAACGGCGAGTACGGTGAGGTTGGCCATCCGGTAGTGCATTACCTGCATCGACCG
GCTCCGCGCGACGAGCTTATCGCTTTCTTCGTGGCCAGCGACGTCATGCTGGTCACCCCA
CTACGCGACGGGATGAACCTGGTGGCCAAGGAGTACGTCGCTTGCCGCAGCGATCTTGGC
GGTGCCCTGGTGCTCAGCGAATTCACCGGGGCCGCAGCCGAACTCCGGCACGCATACCTG
GTCAACCCGCACGACCTGGAAGGCGTCAAGGACGGGATAGAGGAAGCGCTCAACCAGACG
GAGGAGGCGGGCCGGCGGCGAATGCGGTCGCTGCGACGCCAAGTGCTCGCCCACGACGTG
GACCGCTGGGCACAGTCGTTTCTCGACGCTCTCGCCGGGGCACACCCGAGGGGCCAAGGC
TAA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Term	TBRXN:TRE6PS alpha,alpha-trehalose-phosphate synthase (UDP-forming) - ISS	active	njamshidi	2012-10-05
	PMID: 10658666 KA. De Smet, A. Weston et al. Three pathways for trehalose biosynthesis in mycobacteria. Microbiology (Reading, Engl.) 2000
Term	EC:2.4.1.15 Alpha,alpha-trehalose-phosphate synthase (UDP-forming). - ISS	active	njamshidi	2012-10-05
	PMID: 10658666 KA. De Smet, A. Weston et al. Three pathways for trehalose biosynthesis in mycobacteria. Microbiology (Reading, Engl.) 2000
Term	TBRXN:TRE6PS alpha,alpha-trehalose-phosphate synthase (UDP-forming) - IDA	active	njamshidi	2012-10-05
	PMID: 10658666 KA. De Smet, A. Weston et al. Three pathways for trehalose biosynthesis in mycobacteria. Microbiology (Reading, Engl.) 2000
Term	EC:2.4.1.15 Alpha,alpha-trehalose-phosphate synthase (UDP-forming). - IDA	active	njamshidi	2012-10-05
	PMID: 10658666 KA. De Smet, A. Weston et al. Three pathways for trehalose biosynthesis in mycobacteria. Microbiology (Reading, Engl.) 2000
Name	ALPHA, ALPHA-TREHALOSE-PHOSPHATE SYNTHASE	active	mjackson	2012-10-05
	Trehalose biosynthesis