Rv3496c - MCE-family protein mce4D
Protein Domains

Gene Information
LocusRv3496c
Symbolmce4D
Gene NameMCE-family protein mce4D
Location3914531 - 3915886 (-)
SpeciesMycobacterium tuberculosis H37Rv complete genome.
LengthGene:1356 bp
Protein:452 aa
External LinksTuberculist
Target Gene Information
String Protein-Protein Interactions
STITCH Chemical-Protein Interactions
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Orthologs
Orthogroup Number25297
Related GenesMAP0567 MAV_0660 Mkms_4702 Mmcs_4614 MSMEG_5897 MT3600 MUL_4059 Mvan_5199 nfa5400
Transcriptional Regulation
Operons View gene in operon browser
Regulatory Network
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Expression Correlation Genes with Correlated Expression
Scatterplot of Gene Expression

Sequence
Proteins
Genomic Sequence
Community Annotations Pending Curatorial Review
FieldValueStatusCreatorDate
InteractionRegulatory Rv3574activepriyadarshinipriyanka20012012-10-05
Co-expression (Functional linkage)
SL. Kendall,P. Burgess,R. Balhana,M. Withers,A. Ten Bokum,JS. Lott,C. Gao,I. Uhia Castro,NG. Stoker Cholesterol utilisation in mycobacteria is controlled by two TetR-type transcriptional regulators; kstR and kstR2. Microbiology (Reading, England) 2010
InteractionRegulatory Rv3574activepriyadarshinipriyanka20012012-10-05
Co-expression (Functional linkage)
SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
InteractionRegulatory Rv3574activeakankshajain.212012-10-05
Co-expression (Functional linkage)
authors,R. Van der Geize,K. Yam,T. Heuser,MH. Wilbrink,H. Hara,MC. Anderton,E. Sim,L. Dijkhuizen,JE. Davies,WW. Mohn,LD. Eltis A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages. Proc. Natl. Acad. Sci. U.S.A. 2007
InteractionRegulatory Rv3574activeakankshajain.212012-10-05
Co-expression (Functional linkage)
SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
InteractionRegulatedBy Rv3574activeyamir.moreno2012-10-05
M.smegmatis orthology based inference. Orthologous pair regulator-target found in M.smegmatis.
SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
InteractionRegulatedBy Rv3574activeyamir.moreno2012-10-05
Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support.
G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008