Rv3501c - hypothetical membrane protein yrbE4A

Expression: Most Significant Conditions for Rv3501c

Protein Domains

Gene Information
Locus	Rv3501c
Symbol	yrbE4A
Gene Name	hypothetical membrane protein yrbE4A
Location	3920097 - 3920861 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:765 bp Protein:255 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	26544
Related Genes	MAP0562 MAV_0655 Mkms_4707 Mmcs_4619 MSMEG_5902 MT3605 MUL_4064 Mvan_5204 nfa5350
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3501c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3501c Transcript 1
MIQQLAVPARAVGGFFEMSMDTARAAFRRPFQFREFLDQTWMVARVSLVPTLLVSIPFTV
LVAFTLNILLREIGAADLSGAGTAFGTITQLGPVVTVLVVAGAGATAICADLGARTIREE
IDAMRVLGIDPIQRLVVPRVLASTLVALLLNGLVCAIGLSGGYAFSVFLQGVNPGAFING
LTVLTGLRELILAEIKALLFGVMAGLVGCYRGLTVKGGPKGVGNAVNETVVYAFICLFVI
NVVMTAIGVRISAQ*

Genomic Sequence

>Rv3501c
TTGATCCAACAACTTGCGGTTCCGGCCCGGGCCGTCGGCGGGTTCTTCGAAATGTCGATG
GACACCGCGCGTGCCGCTTTCCGGCGGCCGTTCCAGTTCCGCGAGTTTTTGGACCAGACC
TGGATGGTGGCCCGCGTTTCGCTAGTCCCGACGTTGCTGGTGTCCATTCCGTTCACGGTC
CTGGTGGCGTTCACCCTCAACATTCTGTTGCGTGAAATTGGGGCCGCCGACTTGTCCGGC
GCCGGAACGGCGTTCGGCACCATCACCCAGCTGGGCCCGGTCGTGACTGTGCTGGTGGTG
GCAGGTGCTGGCGCCACGGCGATCTGCGCCGACCTGGGCGCTCGCACCATCCGTGAGGAA
ATCGACGCGATGCGGGTGCTGGGCATCGACCCAATTCAACGGCTCGTGGTCCCCAGGGTG
TTGGCGTCCACATTGGTTGCGCTGCTGCTCAACGGCTTGGTGTGCGCCATTGGCCTGTCC
GGCGGCTACGCGTTCTCGGTCTTTCTTCAGGGCGTCAACCCGGGTGCGTTTATCAACGGT
CTGACCGTGCTCACCGGACTGCGCGAATTGATACTGGCGGAGATCAAGGCGCTACTGTTC
GGGGTCATGGCCGGGCTGGTCGGGTGTTACCGCGGTCTGACGGTCAAGGGTGGGCCCAAG
GGGGTGGGCAATGCGGTCAACGAGACCGTCGTCTACGCGTTCATCTGCCTTTTCGTGATC
AACGTAGTCATGACCGCTATAGGTGTGCGAATCTCGGCGCAGTAA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv3574	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) SL. Kendall,P. Burgess,R. Balhana,M. Withers,A. Ten Bokum,JS. Lott,C. Gao,I. Uhia Castro,NG. Stoker Cholesterol utilisation in mycobacteria is controlled by two TetR-type transcriptional regulators; kstR and kstR2. Microbiology (Reading, England) 2010
Interaction	Regulatory Rv3574	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	Regulatory Rv3574	active	jgalag	2012-10-05
	Co-expression (Functional linkage) authors,R. Van der Geize,K. Yam,T. Heuser,MH. Wilbrink,H. Hara,MC. Anderton,E. Sim,L. Dijkhuizen,JE. Davies,WW. Mohn,LD. Eltis A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages. Proc. Natl. Acad. Sci. U.S.A. 2007
Interaction	Regulatory Rv3574	active	jgalag	2012-10-05
	Co-expression (Functional linkage) SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	PhysicalInteraction Rv0655	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) authors,SM. Joshi,AK. Pandey,N. Capite,SM. Fortune,EJ. Rubin,CM. Sassetti Characterization of mycobacterial virulence genes through genetic interaction mapping. Proc. Natl. Acad. Sci. U.S.A. 2006
Interaction	RegulatedBy Rv3574	active	yamir.moreno	2012-10-05
	M.smegmatis orthology based inference. Orthologous pair regulator-target found in M.smegmatis. SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	RegulatedBy Rv3574	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008