Rv3502c - short-chain type dehydrogenase/reductase

Expression: Most Significant Conditions for Rv3502c

Protein Domains

Gene Information
Locus	Rv3502c
Symbol	fabG
Gene Name	short-chain type dehydrogenase/reductase
Location	3921087 - 3922040 (-)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:954 bp Protein:318 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	26392
Related Genes	MAP0561 MAV_0654 Mkms_4708 Mmcs_4620 MSMEG_5903 MT3606 MT3612 MUL_4065 Mvan_5205 nfa5340 Rv3507
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3502c
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3502c Transcript 1
MKLTESNRSPRTTNTTDLSGKVAVVTGAAAGLGRAEALGLARLGATVVVNDVASALDASD
VVDEIGAAAADAGAKAVAVAGDISQRATADELLASAVGLGGLDIVVNNAGITRDRMLFNM
SDEEWDAVIAVHLRGHFLLTRNAAAYWRDKAKDAEGGSVFGRLVNTSSEAGLVGPVGQAN
YAAAKAGITALTLSAARALGRYGVCANVICPRARTAMTADVFGAAPDVEAGQIDPLSPQH
VVSLVQFLASPAAAEVNGQVFIVYGPQVTLVSPPHMERRFSADGTSWDPTELTATLRDYF
AGRDPEQSFSATDLMRQ*

Genomic Sequence

>Rv3502c
TTGAAATTGACTGAGTCCAATCGCTCGCCGCGTACCACGAACACGACCGATCTGTCCGGA
AAGGTGGCGGTGGTCACCGGCGCGGCCGCGGGTTTGGGTCGGGCCGAAGCGCTCGGCCTG
GCCCGGTTGGGCGCCACCGTCGTCGTCAACGATGTTGCTTCCGCCCTGGATGCTTCCGAC
GTCGTCGACGAGATCGGCGCCGCCGCTGCCGATGCTGGTGCTAAGGCCGTCGCGGTAGCC
GGTGATATCAGCCAGCGCGCGACGGCCGACGAACTGCTCGCCAGCGCCGTCGGGCTGGGC
GGACTGGACATCGTGGTGAACAATGCCGGCATCACCCGCGACCGGATGCTGTTCAACATG
TCCGACGAGGAGTGGGACGCCGTGATCGCGGTGCACCTGCGCGGCCATTTTCTGCTCACC
CGCAACGCCGCTGCCTACTGGCGGGACAAAGCCAAGGATGCCGAAGGGGGATCGGTCTTC
GGCCGGCTCGTCAACACCTCGTCGGAGGCGGGTCTGGTGGGCCCGGTGGGGCAGGCGAAT
TACGCCGCCGCCAAGGCTGGCATCACCGCGCTAACCCTGTCGGCGGCGCGGGCGCTCGGG
CGCTACGGCGTTTGCGCCAATGTGATTTGTCCGCGGGCGCGCACCGCGATGACGGCCGAT
GTCTTCGGCGCCGCACCCGATGTCGAAGCGGGCCAGATCGACCCGCTGTCGCCGCAGCAT
GTGGTAAGCCTGGTCCAGTTTCTGGCGTCCCCGGCTGCCGCGGAAGTCAACGGTCAGGTG
TTCATCGTCTACGGTCCGCAGGTGACGCTGGTGTCACCGCCGCACATGGAGCGCCGGTTC
AGCGCGGACGGCACGTCCTGGGATCCCACCGAGCTCACCGCGACGCTGCGGGACTACTTT
GCTGGTCGGGATCCGGAACAGAGCTTTTCGGCGACCGATCTGATGCGTCAGTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv3574	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) SL. Kendall,P. Burgess,R. Balhana,M. Withers,A. Ten Bokum,JS. Lott,C. Gao,I. Uhia Castro,NG. Stoker Cholesterol utilisation in mycobacteria is controlled by two TetR-type transcriptional regulators; kstR and kstR2. Microbiology (Reading, England) 2010
Interaction	Regulatory Rv3574	active	priyadarshinipriyanka2001	2012-10-05
	Co-expression (Functional linkage) SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	Regulatory Rv3574	active	jgalag	2012-10-05
	Co-expression (Functional linkage) SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	RegulatedBy Rv3574	active	yamir.moreno	2012-10-05
	M.smegmatis orthology based inference. Orthologous pair regulator-target found in M.smegmatis. SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	RegulatedBy Rv3574	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008