Rv3519 - hypothetical protein

Expression: Most Significant Conditions for Rv3519

Protein Domains

Gene Information
Locus	Rv3519
Symbol
Gene Name	hypothetical protein
Location	3955550 - 3956260 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:711 bp Protein:237 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	3554
Related Genes	MAP0546c MAV_0640 Mkms_4720 Mmcs_4632 MSMEG_5919 MT3620 MUL_4078 Mvan_5218 nfa41380
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3519
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3519 Transcript 1
MPVSQHTIAGTVLTMPVRIRTANLHSAMFSVPADPAQRLIDYSGLRVCEYLPGKAIVMQM
LVRYVDGDLGRYHEYGTAIMVNPPGTQRRGPRALTRAAAFIHHLPVDQVFTLEAGRTIWG
FPKIMADFNVTDGRRFGFDVSADGRLIAGIEFSTGLPVPTLGWQMLKTYSHHDGVTREIP
WEMKVSGLRARLGGARLRLGDHPYAKELASLGLPKRALLSQSAANVEMTFGDGHPI*

Genomic Sequence

>Rv3519
ATGCCCGTCTCGCAACACACCATCGCCGGCACGGTGCTCACCATGCCGGTGCGCATTCGC
ACCGCCAACCTGCATTCCGCGATGTTCTCGGTGCCCGCCGACCCAGCGCAGCGCCTCATC
GACTACAGCGGGCTGCGGGTGTGCGAATACCTGCCCGGTAAGGCAATCGTGATGCAGATG
CTGGTGCGCTACGTCGACGGGGATTTGGGGCGATACCACGAGTACGGCACCGCGATCATG
GTGAACCCGCCCGGCACCCAACGCCGCGGGCCCAGAGCCCTCACCCGAGCCGCCGCGTTC
ATCCATCATCTGCCGGTAGATCAGGTGTTCACGCTTGAGGCCGGGCGCACCATCTGGGGC
TTCCCGAAGATCATGGCGGACTTCAACGTCACCGACGGCCGGAGGTTCGGCTTCGACGTC
AGCGCCGACGGACGGTTGATCGCCGGGATCGAGTTCAGCACCGGCCTGCCGGTGCCGACC
CTCGGGTGGCAAATGTTGAAGACCTACTCCCACCATGACGGCGTAACTCGCGAGATTCCC
TGGGAAATGAAAGTCTCGGGCCTGCGCGCCCGGCTCGGCGGCGCCCGACTGCGGTTGGGA
GACCATCCCTACGCCAAAGAACTGGCATCGCTGGGCCTGCCGAAGCGGGCTCTGTTGTCC
CAGTCGGCGGCCAACGTAGAAATGACCTTCGGCGACGGTCACCCGATCTGA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv3574	active	salluamity1	2012-10-05
	Co-expression (Functional linkage) authors,RD. Fleischmann,D. Alland,JA. Eisen,L. Carpenter,O. White,J. Peterson,R. DeBoy,R. Dodson,M. Gwinn,D. Haft,E. Hickey,JF. Kolonay,WC. Nelson,LA. Umayam,M. Ermolaeva,SL. Salzberg,A. Delcher,T. Utterback,J. Weidman,H. Khouri,J. Gill,A. Mikula,W. Bishai,WR. Jacobs Jr,JC. Venter,CM. Fraser Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains. J. Bacteriol. 2002
Interaction	Regulatory Rv3574	active	salluamity1	2012-10-05
	Co-expression (Functional linkage) authors,D. Alland,DW. Lacher,MH. Hazbón,AS. Motiwala,W. Qi,RD. Fleischmann,TS. Whittam Role of large sequence polymorphisms (LSPs) in generating genomic diversity among clinical isolates of Mycobacterium tuberculosis and the utility of LSPs in phylogenetic analysis. J. Clin. Microbiol. 2007
Interaction	Regulatory Rv3574	active	salluamity1	2012-10-05
	Co-expression (Functional linkage) SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	RegulatedBy Rv3574	active	yamir.moreno	2012-10-05
	M.smegmatis orthology based inference. Orthologous pair regulator-target found in M.smegmatis. SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	RegulatedBy Rv3574	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008