Rv3527 - hypothetical protein

Expression: Most Significant Conditions for Rv3527

Protein Domains

Gene Information
Locus	Rv3527
Symbol
Gene Name	hypothetical protein
Location	3963605 - 3964054 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:450 bp Protein:150 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	13035
Related Genes	MAP0538c MAV_0632 Mkms_4729 Mmcs_4641 MSMEG_5927 MT3627 MUL_4090 Mvan_5226 nfa4760
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3527
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3527 Transcript 1
MPDDQPAVPDVDRLARSMLLLHGDHHDHNDSPEQHRTCGSWSKSRDFADDPQRAAAVREA
SRAERDRYLTSGLQPVDCRFCHVTVTVKRLGPGHTAVQWNTEASRRCAYFTELRARGGDS
ARTRSCPRLTDSIEHAVAEGYLEHHDPNR*

Genomic Sequence

>Rv3527
ATGCCTGACGATCAGCCGGCGGTTCCCGACGTCGATCGGCTGGCCCGGTCGATGCTACTG
CTGCACGGTGATCATCACGATCACAACGATTCCCCCGAGCAACACCGCACATGTGGATCC
TGGTCGAAGTCAAGGGATTTCGCTGACGACCCGCAGCGTGCTGCCGCGGTGCGCGAAGCC
AGCCGCGCCGAGCGCGACCGTTATCTGACCTCAGGCCTGCAACCGGTGGATTGCCGGTTC
TGCCATGTCACGGTGACCGTAAAGAGGCTGGGGCCGGGTCATACCGCTGTGCAATGGAAC
ACCGAGGCGTCGCGGCGCTGCGCGTACTTCACCGAGCTGCGGGCACGCGGCGGGGATTCC
GCACGCACCAGGTCCTGTCCCCGGCTGACCGACAGCATCGAACACGCAGTGGCCGAGGGC
TACTTGGAGCACCACGACCCAAACCGATAA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	Regulatory Rv3574	active	salluamity1	2012-10-05
	Co-expression (Functional linkage) authors,K. Pethe,DL. Swenson,S. Alonso,J. Anderson,C. Wang,DG. Russell Isolation of Mycobacterium tuberculosis mutants defective in the arrest of phagosome maturation. Proc. Natl. Acad. Sci. U.S.A. 2004
Interaction	Regulatory Rv3574	active	salluamity1	2012-10-05
	Co-expression (Functional linkage) SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	RegulatedBy Rv3574	active	yamir.moreno	2012-10-05
	M.smegmatis orthology based inference. Orthologous pair regulator-target found in M.smegmatis. SL. Kendall, M. Withers et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 2007
Interaction	RegulatedBy Rv3574	active	yamir.moreno	2012-10-05
	Literature previously reported link (from Balazsi et al. 2008). Traceable author statement to experimental support. G. Balázsi, AP. Heath et al. The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol. Syst. Biol. 2008