Rv3586 - conserved hypothetical protein

Expression: Most Significant Conditions for Rv3586

Protein Domains

Gene Information
Locus	Rv3586
Symbol
Gene Name	conserved hypothetical protein
Location	4027891 - 4028967 (+)
Species	Mycobacterium tuberculosis H37Rv complete genome.
Length	Gene:1077 bp Protein:359 aa
External Links	Tuberculist Target Gene Information String Protein-Protein Interactions STITCH Chemical-Protein Interactions Search Google Scholar
Orthologs
Orthogroup Number	1030
Related Genes	Acel_0229 CE2525 cg2951 MAP0472c MAV_0567 Mkms_4829 Mmcs_4743 MSMEG_6080 MT3692 MUL_4162 Mvan_5343 PPA0311 SAV4709
Transcriptional Regulation
Operons	View gene in operon browser
Regulatory Network	Search for regulators of Rv3586
Expression Correlation	Genes with Correlated Expression Scatterplot of Gene Expression

Sequence

Proteins

>Rv3586 Transcript 1
MHAVTRPTLREAVARLAPGTGLRDGLERILRGRTGALIVLGHDENVEAICDGGFSLDVRY
AATRLRELCKMDGAVVLSTDGSRIVRANVQLVPDPSIPTDESGTRHRSAERAAIQTGYPV
ISVSHSMNIVTVYVRGERHVLTDSATILSRANQAIATLERYKTRLDEVSRQLSRAEIEDF
VTLRDVMTVVQRLELVRRIGLVIDYDVVELGTDGRQLRLQLDELLGGNDTARELIVRDYH
ANPEPPSTGQINATLDELDALSDGDLLDFTALAKVFGYPTTTEAQDSTLSPRGYRAMAGI
PRLQFAHADLLVRAFGTLQGLLAASAGDLQSVDGIGAMWARHVREGLSQLAESTISDQ*

Genomic Sequence

>Rv3586
ATGCACGCTGTGACTCGTCCGACCCTGCGTGAGGCTGTCGCCCGCCTAGCCCCGGGCACT
GGGCTGCGGGACGGCCTGGAGCGTATCCTGCGCGGCCGCACTGGTGCCCTGATCGTGCTG
GGCCATGACGAGAATGTCGAGGCCATCTGCGATGGTGGCTTCTCCCTCGATGTCCGCTAT
GCAGCAACCCGGCTACGCGAGCTGTGCAAGATGGACGGCGCCGTGGTGCTGTCCACCGAC
GGCAGCCGCATCGTGCGGGCCAACGTGCAACTGGTACCGGATCCGTCGATCCCCACCGAC
GAATCGGGGACCCGGCACCGCTCGGCCGAGCGGGCCGCGATCCAGACCGGTTACCCGGTG
ATCTCAGTGAGCCACTCGATGAACATCGTGACCGTCTACGTCCGCGGGGAACGTCACGTA
TTGACCGACTCGGCAACCATCCTGTCGCGGGCCAACCAGGCCATCGCAACCCTGGAGCGG
TACAAAACCAGGCTCGACGAGGTCAGCCGGCAACTGTCCAGGGCAGAAATCGAGGACTTC
GTCACGCTGCGCGATGTGATGACGGTGGTGCAACGCCTCGAGCTGGTCCGGCGAATCGGG
CTGGTGATCGACTACGACGTGGTCGAACTCGGCACTGATGGTCGTCAGCTGCGGCTGCAG
CTCGACGAGTTGCTCGGCGGCAACGACACCGCCCGGGAATTGATCGTGCGCGATTACCAC
GCCAACCCGGAACCACCGTCCACGGGGCAAATCAATGCCACCCTGGACGAACTGGACGCC
CTGTCGGACGGCGACCTCCTCGATTTCACCGCGCTGGCAAAGGTTTTCGGATATCCGACG
ACCACGGAAGCGCAGGATTCGACGCTGAGCCCGCGTGGCTACCGCGCGATGGCCGGTATC
CCCCGGCTCCAGTTCGCCCATGCCGACCTGCTGGTCCGGGCGTTCGGAACGTTGCAGGGT
CTGCTGGCGGCCAGCGCCGGCGATCTGCAATCAGTGGACGGCATCGGCGCCATGTGGGCC
CGTCATGTGCGCGAGGGGTTGTCACAGCTGGCGGAATCGACCATCAGCGATCAATAA

Community Annotations Pending Curatorial Review

Field	Value	Status	Creator	Date
Interaction	RegulatedBy Rv0491	active	yamir.moreno	2012-10-05
	Microarrays. mRNA levels of regulated element measured and compared between wild-type and trans-element mutation (knockout, over expression etc.) performed by using microarray (or macroarray) experiments.. T. Parish, DA. Smith et al. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology (Reading, Engl.) 2003